MIRAGE upload

In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.

PubMed Entry

GlyToucan Accession Number: G13249MW

Peak	Intensity
368.2	183.0
Annotations: Y
424.1	737.0
Annotations: ^{1,3}A_{Man}Y ^{0,4}A_{Man}Y C^{0,4}X_{Gal} C^{1,3}X_{Gal} C^{2,4}X_{Gal} C^{0,4}X_{Gal} C^{1,3}X_{Gal} C^{2,4}X_{Gal}
466.2	164.0
468.3	187.0
Annotations: C^{2,5}X_{NeuAc}
470.3	104.0
Annotations: C
503.2	391.0
Annotations: Y^{0,3}X_{GlcNAc}
553.3	553.0
Annotations: Z
554.3	144.0
Annotations: B^{1,5}X_{GlcNAc} B^{1,5}X_{GlcNAc} B^{2,4}X_{NeuAc} ^{3,5}A_{GlcNAc}Z ^{1,4}A_{GlcNAc}Y
556.7	407.0
571.2	224.0
Annotations: Y
613.3	102.0
Annotations: ^{0,2}X_{Man} ^{1,5}A_{GlcNAc}Y
616.2	134.0
Annotations: CY
627.8	247.0
Annotations: BY CZ
647.5	195.0
655.2	691.0
Annotations: B
670.3	223.0
Annotations: ^{2,5}X_{GlcNAc}Z ^{2,5}X_{GlcNAc}Z ^{2,5}A_{Man}Z Z^{0,3}X_{NeuAc}
671.2	203.0
Annotations: ^{2,5}A_{Man}Z Z^{0,3}X_{NeuAc} ^{0,2}X_{GlcNAc}Y ^{0,2}X_{GlcNAc}Y
673.3	278.0
Annotations: C
688.0	230.0
Annotations: C^{1,3}X_{Man} C^{2,4}X_{GlcNAc} ^{0,2}A_{Man}Y Y^{3,5}X_{NeuAc}
688.4	479.0
772.3	301.0
799.3	123.0
803.3	216.0
Annotations: Z
807.2	114.0
816.8	166.0
Annotations: B
818.1	308.0
Annotations: ^{3,5}A_{GlcNAc}Z ^{1,4}A_{GlcNAc}Y ^{1,4}A_{GlcNAc}Y C^{0,3}X_{GlcNAc} C^{0,3}X_{GlcNAc}
818.4	218.0
Annotations: ^{1,4}A_{GlcNAc}Y ^{1,4}A_{GlcNAc}Y C^{0,3}X_{GlcNAc} C^{0,3}X_{GlcNAc}
831.4	366.0
Annotations: ^{1,5}A_{GlcNAc}Z ^{1,5}A_{GlcNAc}Z ^{1,5}A_{Man}Z ^{1,5}A_{Man}Z B^{0,4}X_{Gal} B^{1,3}X_{Gal} B^{2,4}X_{Gal} B^{0,4}X_{Gal} B^{1,3}X_{Gal} B^{2,4}X_{Gal}
835.4	1828.0
Annotations: C
836.4	1558.0
846.8	106.0
875.4	270.0
Annotations: ZZ ZZ
875.8	240.0
Annotations: ZZ ZZ
876.8	364.0
Annotations: C^{1,5}X_{Gal} C^{1,5}X_{Gal} ^{0,4}A_{Man} ^{0,3}X_{GlcNAc}Y Y^{3,5}X_{GlcNAc} ^{3,5}X_{GlcNAc}Y Y^{3,5}X_{GlcNAc} ^{3,5}X_{GlcNAc}Y C^{1,5}X_{GlcNAc} C^{1,5}X_{GlcNAc}
877.3	351.0
Annotations: YZ ZY
891.2	108.0
Annotations: B
926.8	283.0
Annotations: B^{0,2}X_{NeuAc} Z^{1,5}X_{Fuc}
935.4	174.0
Annotations: B
936.4	135.0
Annotations: C^{1,5}X_{NeuAc} Y^{2,5}X_{NeuAc} Y^{2,5}X_{NeuAc}
936.9	141.0
937.3	319.0
944.4	174.0
Annotations: C
948.0	707.0
Annotations: ZZ ZZ
948.9	280.0
Annotations: ZY YZ ZY YZ
950.3	108.0
Annotations: Y^{1,4}X_{Fuc} ^{0,3}X_{GlcNAc} ^{0,3}X_{Gal}Y ^{1,4}X_{Gal}Y ^{0,3}X_{GlcNAc}Y ^{0,3}X_{Gal}Y ^{1,4}X_{Gal}Y ^{0,3}X_{GlcNAc}Y C^{0,3}X_{NeuAc}
956.4	304.0
Annotations: YZ ZY YZ ZY
957.8	382.0
Annotations: YY YY
965.3	2776.0
Annotations: CY CY
965.9	945.0
Annotations: YY YY
966.4	894.0
966.9	369.0
Annotations: Y^{1,4}X_{GlcNAc}
967.7	297.0
Annotations: Y^{1,4}X_{GlcNAc}
968.1	281.0
968.9	311.0
970.2	127.0
Annotations: B^{1,5}X_{Gal} B^{1,5}X_{Gal} Z^{0,4}X_{NeuAc} Z^{0,2}X_{Gal} Z^{0,4}X_{NeuAc} ^{0,2}X_{Gal}Z
973.3	308.0
Annotations: Y^{0,4}X_{Fuc}
984.1	128.0
994.3	522.0
Annotations: YZ ZY
994.8	609.0
Annotations: Y
996.0	186.0
1001.2	231.0
Annotations: ^{1,4}A_{GlcNAc} C^{0,3}X_{Gal} C^{1,4}X_{Gal} C^{0,3}X_{Gal} C^{1,4}X_{Gal} Z^{3,5}X_{Fuc} Z^{3,5}X_{Fuc}
1008.9	138.0
Annotations: C^{3,5}X_{Gal} C^{3,5}X_{Gal} ^{1,5}X_{Gal}Y Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{1,5}X_{Gal}Y Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{0,4}X_{Gal}Y ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y
1016.4	254.0
Annotations: Y^{1,5}X_{Fuc} Y^{0,4}X_{Fuc} Y^{1,3}X_{NeuAc} Y^{0,4}X_{Fuc} Y^{1,3}X_{NeuAc}
1017.4	859.0
1018.3	187.0
1019.2	160.0
1020.5	201.0
Annotations: ^{2,4}X_{GlcNAc}Z Z^{2,4}X_{GlcNAc} Z^{2,4}X_{GlcNAc} Z^{0,2}X_{NeuAc} Z^{0,2}X_{NeuAc}
1022.4	167.0
Annotations: ^{0,3}X_{GlcNAc}Y Y^{3,5}X_{GlcNAc} ^{1,5}A_{GlcNAc} Z^{2,5}X_{Fuc} ^{3,5}X_{GlcNAc}Y ^{0,3}X_{GlcNAc}Y
1028.3	252.0
Annotations: ^{2,4}X_{GlcNAc}Z ^{2,4}X_{GlcNAc}Z
1029.9	412.0
Annotations: Z Z
1031.5	578.0
Annotations: Y^{2,5}X_{Fuc}
1035.3	179.0
Annotations: BZ
1036.5	160.0
Annotations: B
1036.7	259.0
Annotations: B
1036.8	352.0
Annotations: B
1037.3	282.0
Annotations: B
1037.9	243.0
Annotations: ^{0,2}X_{NeuAc}Y Z^{3,5}X_{Fuc} Y^{2,5}X_{NeuAc} Y^{2,5}X_{NeuAc} Y^{2,4}X_{GlcNAc}
1039.0	747.0
Annotations: Y Y
1039.3	259.0
Annotations: Y Y
1039.6	514.0
Annotations: ^{2,4}A_{GlcNAc}Y
1039.9	452.0
1040.5	407.0
1040.8	434.0
1041.9	134.0
1049.4	345.0
Annotations: ZZ ZZ
1049.5	389.0
Annotations: ZZ ZZ
1049.9	1052.0
Annotations: YZ ZY
1050.8	300.0
Annotations: ZY YZ
1051.3	118.0
Annotations: ^{0,3}A_{GlcNAc}Z
1053.5	194.0
Annotations: BY CZ
1058.4	328.0
Annotations: YZ ZY YZ ZY
1058.9	560.0
Annotations: YY
1059.4	115.0
Annotations: YY
1060.3	158.0
1069.2	147.0
Annotations: ^{0,3}A_{GlcNAc}Y
1072.8	434.0
Annotations: ^{1,5}X_{Gal}Z Z^{1,5}X_{Fuc} ^{1,5}X_{Gal}Z Z^{1,5}X_{Fuc}
1076.3	108.0
Annotations: Y
1077.0	625.0
1079.6	547.0
Annotations: ^{0,4}X_{NeuAc}Z ^{0,2}X_{Gal}Z Z^{0,2}X_{Fuc} ^{0,2}X_{Gal}Z Z^{0,2}X_{Fuc} Z^{2,5}X_{Gal} ^{2,5}X_{Gal}Z
1087.4	207.0
Annotations: ^{2,5}X_{Gal}Z Z^{2,5}X_{Fuc} ^{2,5}X_{Gal}Z Z^{2,5}X_{Fuc}
1092.9	110.0
1102.0	605.0
Annotations: ^{3,5}X_{Gal}Z Z^{3,5}X_{Fuc} ^{3,5}X_{Gal}Z Z^{3,5}X_{Fuc}
1102.4	267.0
Annotations: ^{3,5}X_{Gal}Z Z^{3,5}X_{Fuc} ^{3,5}X_{Gal}Z Z^{3,5}X_{Fuc}
1109.4	203.0
Annotations: ^{3,5}A_{GlcNAc}Z ^{0,4}X_{Gal}Z ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{0,4}X_{Fuc} ^{0,4}X_{Gal}Z ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{0,4}X_{Fuc} Z^{1,3}X_{NeuAc} Z^{1,3}X_{NeuAc}
1109.9	538.0
Annotations: ^{1,4}A_{GlcNAc}Y
1110.5	1005.0
Annotations: ^{0,4}X_{Gal}Y ^{1,4}A_{GlcNAc}Y ^{2,4}X_{GlcNAc} Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y ^{2,4}X_{GlcNAc} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{0,2}X_{NeuAc}
1110.8	365.0
Annotations: ^{1,4}A_{GlcNAc}Y ^{2,4}X_{GlcNAc} Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{0,4}X_{Gal}Y ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y ^{2,4}X_{GlcNAc} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{0,2}X_{NeuAc}
1111.0	586.0
Annotations: Y^{3,5}X_{Fuc} ^{0,2}X_{NeuAc} ^{3,5}X_{Gal}Y Y^{3,5}X_{Fuc} ^{3,5}X_{Gal}Y
1111.5	319.0
Annotations: ^{3,5}X_{Gal}Y Y^{3,5}X_{Fuc} ^{3,5}X_{Gal}Y Y^{3,5}X_{Fuc} ^{1,5}X_{NeuAc}
1111.9	216.0
Annotations: ^{1,5}X_{NeuAc}
1113.5	118.0
Annotations: ^{2,4}A_{GlcNAc}Y
1114.3	319.0
1119.0	701.0
Annotations: ^{2,5}X_{NeuAc}
1119.4	335.0
1119.9	246.0
1120.5	189.0
1120.7	245.0
1120.9	143.0
1122.9	410.0
1123.5	102.0
1131.4	1722.0
Annotations: Z Z
1132.0	3584.0
1132.5	1061.0
1132.8	614.0
1133.5	135.0
Annotations: ^{3,5}X_{NeuAc}
1134.4	125.0
1139.4	2117.0
Annotations: Z
1140.0	1705.0
Annotations: Y Y
1140.5	4739.0
Annotations: Y Y
1141.0	3568.0
1141.3	1321.0
1141.5	1852.0
1141.8	721.0
1142.0	627.0
1142.5	234.0
1143.0	183.0
Annotations: ^{0,3}A_{GlcNAc}Y C^{1,4}X_{Man}
1148.4	695.0
Annotations: Y
1149.0	997.0
1150.0	239.0
1155.4	259.0
Annotations: ^{0,2}A_{GlcNAc}Z B^{1,3}X_{Man} ^{0,2}A_{Man}Z
1161.5	722.0
Annotations: ^{0,4}X_{NeuAc} ^{0,2}X_{Gal} ^{0,2}X_{Gal}
1163.0	290.0
1163.5	473.0
Annotations: ^{1,4}X_{NeuAc}
1168.0	741.0
1170.5	375.0
Annotations: ^{2,4}X_{NeuAc}
1173.9	154.0
Annotations: ^{0,2}A_{Man}Y ^{0,2}A_{GlcNAc}Y C^{1,3}X_{Man}
1182.3	105.0
Annotations: CZ BY
1182.9	736.0
Annotations: BY CZ
1191.0	237.0
Annotations: ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal}
1191.5	2578.0
Annotations: ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal}
1191.9	2502.0
Annotations: ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal}
1192.5	1778.0
Annotations: ^{3,5}X_{Fuc}
1192.9	476.0
Annotations: ^{3,5}X_{Fuc}
1200.5	2170.0
Annotations: CY
1200.9	1797.0
Annotations: CY
1201.5	1278.0
1202.0	368.0
1203.0	182.0
1203.2	270.0
1203.5	267.0
1203.9	364.0
1212.0	520.0
1212.5	1980.0
1212.9	513.0
1213.5	1224.0
1213.9	196.0
1214.3	372.0
1218.5	110.0
1220.5	1054.0
1220.7	191.0
1220.9	169.0
1221.5	1775.0
Annotations:
1242.3	108.0
Annotations: YZ ZY YZ ZY YZ ZY
1245.1	123.0
1245.5	104.0
1260.7	180.0
Annotations: YY YY YY
1262.6	258.0
1344.6	411.0
Annotations: B^{3,5}X_{GlcNAc} Z^{1,3}X_{Man} Z^{1,3}X_{Man}
1345.0	170.0
1345.5	172.0
1346.5	408.0
Annotations: C^{1,4}X_{Man} C^{0,3}X_{GlcNAc} ^{1,4}A_{GlcNAc}Y Y^{2,5}X_{NeuAc}
1349.5	145.0
1386.9	112.0
Annotations: ZZ ZZ
1392.6	161.0
1447.4	282.0
Annotations: Y^{0,2}X_{Fuc}
1478.4	152.0
Annotations: ^{2,4}A_{GlcNAc}Y ^{1,5}A_{Man}Y ^{1,5}A_{Man}Y
1493.6	517.0
Annotations: Y^{3,5}X_{Fuc}
1526.6	251.0
1583.8	121.0
1590.7	173.0
1591.8	366.0
1630.0	133.0
1643.8	263.0
1709.5	511.0
Annotations: BY BY CZ CZ BY BY CZ CZ
1710.6	321.0
1711.7	221.0
Annotations: ^{1,4}A_{GlcNAc}Y Z^{3,5}X_{Fuc}
1728.6	190.0
1747.5	169.0
1751.5	141.0
Annotations: ZZ ZZ
1767.0	373.0
Annotations: ^{2,4}X_{GlcNAc}Z
1787.6	231.0
Annotations: Y
1788.8	338.0
Annotations: C^{2,4}X_{NeuAc}
1829.8	103.0
Annotations: ^{0,2}A_{Man} ^{0,2}A_{GlcNAc}Y ^{0,2}A_{GlcNAc}Y C^{0,4}X_{Gal} C^{1,3}X_{Gal} C^{2,4}X_{Gal} C^{0,4}X_{Gal} C^{1,3}X_{Gal} C^{2,4}X_{Gal}
1844.7	227.0
Annotations: YY
1871.6	330.0
Annotations: B
1872.8	331.0
Annotations: Y^{1,5}X_{Fuc}
1873.5	222.0
Annotations: C^{1,5}X_{NeuAc} Y^{2,5}X_{NeuAc} Y^{2,5}X_{NeuAc}
1889.7	1060.0
Annotations: C
1890.0	571.0
Annotations: C
1890.7	1167.0
1890.9	897.0
1891.8	264.0
1895.6	169.0
1912.7	419.0
Annotations: BY BY CZ CZ
1914.0	231.0
1914.3	337.0
Annotations: YZ YZ ZY ZY
1917.0	183.0
Annotations: YY YY
1932.6	260.0
Annotations: YY YY
1932.8	270.0
Annotations: YY YY
1942.7	185.0
Annotations: ^{1,5}X_{GlcNAc}Z ^{1,5}X_{GlcNAc}Z Z^{1,5}X_{Fuc} Z^{1,5}X_{Fuc}
1973.8	537.0
Annotations: B^{2,4}X_{NeuAc}
1974.8	165.0
Annotations: Y^{0,2}X_{Fuc} Y^{0,2}X_{Fuc} Y^{2,5}X_{Gal} ^{2,5}X_{Gal}Y
1990.9	189.0
Annotations: Y
1991.1	323.0
Annotations: Y
1991.9	321.0
Annotations: C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc}
1992.1	194.0
Annotations: C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc}
1992.9	187.0
2015.7	220.0
Annotations: ^{0,2}X_{GlcNAc}Y ^{0,2}X_{GlcNAc}Y ^{2,5}X_{GlcNAc}Y Y^{2,5}X_{GlcNAc}
2020.7	275.0
Annotations: Y^{3,5}X_{Fuc} Y^{3,5}X_{Fuc}
2021.9	188.0
2037.9	150.0
2058.6	194.0
Annotations: ^{0,2}X_{NeuAc}Z Z^{2,5}X_{NeuAc} Z^{2,5}X_{NeuAc}
2061.7	276.0
Annotations: ^{3,5}X_{GlcNAc}Y ^{3,5}X_{GlcNAc}Y
2063.6	143.0
2074.8	433.0
Annotations: B
2075.8	192.0
Annotations: ^{2,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y
2076.0	354.0
Annotations: ^{2,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y
2076.6	385.0
Annotations: ^{0,2}X_{NeuAc}Y Z^{3,5}X_{Fuc} Y^{2,5}X_{NeuAc} Y^{2,5}X_{NeuAc}
2078.8	112.0
Annotations: Y Y
2080.0	213.0
2092.8	291.0
Annotations: C
2093.1	261.0
Annotations: C
2093.6	172.0
2094.9	413.0
Annotations: Y^{3,5}X_{Fuc}
2110.9	164.0
2136.0	187.0
Annotations: YY YY
2139.0	388.0
2142.8	354.0
2151.7	157.0
2152.5	189.0
Annotations: Y
2152.8	483.0
Annotations: Y
2153.8	987.0
2154.1	216.0
2154.8	376.0
2155.3	171.0
2156.8	492.0