In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.
GlyToucan Accession Number: G13249MW
Peak | Intensity |
---|---|
368.2 | 183.0 |
Annotations: Y |
|
424.1 | 737.0 |
Annotations: ^{1,3}A_{Man} ^{0,4}A_{Man}Y C^{0,2}X_{Gal} |
|
466.2 | 164.0 |
Annotations: ^{1,3}A_{Man}Z ^{2,4}A_{Man}Z B^{0,4}X_{Gal} B^{1,3}X_{Gal} B^{2,4}X_{Gal} C^{2,5}X_{GlcNAc} |
|
468.3 | 187.0 |
Annotations: C^{2,5}X_{NeuAc} |
|
470.3 | 104.0 |
Annotations: C |
|
503.2 | 391.0 |
Annotations: B^{3,5}X_{NeuAc} Y^{0,3}X_{GlcNAc} |
|
553.3 | 553.0 |
Annotations: Z |
|
554.3 | 144.0 |
Annotations: B^{1,5}X_{GlcNAc} B^{2,4}X_{NeuAc} ^{1,4}A_{Man}Y C^{0,3}X_{Gal} C^{1,4}X_{Gal} |
|
556.7 | 407.0 |
Annotations: YY |
|
571.2 | 224.0 |
Annotations: Y |
|
613.3 | 102.0 |
Annotations: ^{0,2}X_{Man} |
|
616.2 | 134.0 |
Annotations: CY |
|
627.8 | 247.0 |
Annotations: ^{2,4}A_{GlcNAc}Z |
|
647.5 | 195.0 |
655.2 | 691.0 |
Annotations: B |
|
670.3 | 223.0 |
Annotations: BZ |
|
671.2 | 203.0 |
Annotations: ^{2,5}A_{Man}Z ^{0,2}X_{GlcNAc}Y |
|
673.3 | 278.0 |
Annotations: C |
|
688.0 | 230.0 |
Annotations: BY CZ |
|
688.4 | 479.0 |
Annotations: BY CZ |
|
772.3 | 301.0 |
799.3 | 123.0 |
Annotations: BZ |
|
803.3 | 216.0 |
Annotations: YZ ZY YZ ZY ZY YZ YZ ZY ZY YZ |
|
807.2 | 114.0 |
816.8 | 166.0 |
Annotations: BY CZ |
|
818.1 | 308.0 |
Annotations: ^{3,5}A_{GlcNAc}Z ^{1,4}A_{GlcNAc}Y ^{1,4}A_{GlcNAc}Y C^{0,3}X_{GlcNAc} C^{1,4}X_{Man} C^{0,3}X_{GlcNAc} |
|
818.4 | 218.0 |
Annotations: ^{1,4}A_{GlcNAc}Y ^{1,4}A_{GlcNAc}Y C^{0,3}X_{GlcNAc} C^{1,4}X_{Man} C^{0,3}X_{GlcNAc} |
|
831.4 | 366.0 |
Annotations: ^{1,5}A_{GlcNAc}Z ^{1,5}A_{GlcNAc}Z ^{1,5}A_{Man}Z ^{1,5}A_{Man}Z ^{0,3}X_{GlcNAc}Y |
|
835.4 | 1828.0 |
Annotations: CY |
|
836.4 | 1558.0 |
846.8 | 106.0 |
Annotations: ^{2,4}X_{GlcNAc}Y |
|
875.4 | 270.0 |
Annotations: ZZ ZZ YZ ZY |
|
875.8 | 240.0 |
Annotations: ZZ ZZ YZ ZY |
|
876.8 | 364.0 |
Annotations: YY |
|
877.3 | 351.0 |
Annotations: YY YZ ZY |
|
891.2 | 108.0 |
Annotations: BY BY CZ CZ BY CZ |
|
926.8 | 283.0 |
Annotations: B^{0,2}X_{NeuAc} ^{1,3}X_{Man}Z Z^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Z Z^{1,5}X_{Fuc} |
|
935.4 | 174.0 |
Annotations: B |
|
936.4 | 135.0 |
Annotations: C^{1,5}X_{NeuAc} ^{2,5}X_{NeuAc}Y Y^{2,5}X_{NeuAc} |
|
936.9 | 141.0 |
937.3 | 319.0 |
944.4 | 174.0 |
Annotations: C |
|
948.0 | 707.0 |
Annotations: ZZ ZZ |
|
948.9 | 280.0 |
Annotations: Z |
|
950.3 | 108.0 |
Annotations: Y^{1,4}X_{Fuc} Y^{0,3}X_{GlcNAc} ^{0,3}X_{GlcNAc}Y Y^{0,3}X_{Gal} Y^{1,4}X_{Gal} ^{0,3}X_{Gal}Y ^{1,4}X_{Gal}Y ^{0,3}X_{GlcNAc} C^{0,3}X_{NeuAc} |
|
956.4 | 304.0 |
Annotations: YZ ZY YZ ZY |
|
957.8 | 382.0 |
Annotations: Y |
|
965.3 | 2776.0 |
Annotations: CY CY |
|
965.9 | 945.0 |
Annotations: YY YY |
|
966.4 | 894.0 |
966.9 | 369.0 |
Annotations: Y^{1,4}X_{GlcNAc} |
|
967.7 | 297.0 |
Annotations: Y^{1,4}X_{GlcNAc} |
|
968.1 | 281.0 |
968.9 | 311.0 |
970.2 | 127.0 |
Annotations: B^{1,5}X_{Gal} B^{1,5}X_{Gal} ^{0,2}X_{Gal}Z ^{0,4}X_{NeuAc}Z Z^{0,4}X_{NeuAc} Z^{0,2}X_{Gal} |
|
973.3 | 308.0 |
Annotations: Y^{0,4}X_{Fuc} |
|
984.1 | 128.0 |
994.3 | 522.0 |
Annotations: ZY YZ |
|
994.8 | 609.0 |
Annotations: Y |
|
996.0 | 186.0 |
1001.2 | 231.0 |
Annotations: C^{0,3}X_{Gal} C^{1,4}X_{Gal} ^{1,4}A_{GlcNAc} C^{0,3}X_{Gal} C^{1,4}X_{Gal} Z^{3,5}X_{Fuc} Z^{3,5}X_{Fuc} |
|
1008.9 | 138.0 |
Annotations: C^{3,5}X_{Gal} C^{3,5}X_{Gal} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{0,4}X_{Gal}Y ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{1,5}X_{Gal} ^{1,5}X_{Gal}Y ^{1,3}X_{Man} Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} C^{0,3}X_{NeuAc} |
|
1016.4 | 254.0 |
Annotations: ^{1,3}X_{NeuAc}Y Y^{1,3}X_{NeuAc} Y^{1,5}X_{Fuc} Y^{0,4}X_{Fuc} Y^{0,4}X_{Fuc} |
|
1017.4 | 859.0 |
1018.3 | 187.0 |
1019.2 | 160.0 |
1020.5 | 201.0 |
Annotations: BY CZ |
|
1022.4 | 167.0 |
Annotations: ^{0,3}X_{GlcNAc}Y ^{0,3}X_{GlcNAc}Y Y^{3,5}X_{GlcNAc} ^{3,5}X_{GlcNAc}Y ^{1,5}A_{GlcNAc} Z^{2,5}X_{Fuc} |
|
1028.3 | 252.0 |
Annotations: ^{2,4}X_{GlcNAc}Z ^{2,4}X_{GlcNAc}Z |
|
1029.9 | 412.0 |
Annotations: Z Z |
|
1031.5 | 578.0 |
Annotations: Y^{2,5}X_{Fuc} |
|
1035.3 | 179.0 |
1036.5 | 160.0 |
Annotations: B |
|
1036.7 | 259.0 |
Annotations: B |
|
1036.8 | 352.0 |
Annotations: B |
|
1037.3 | 282.0 |
Annotations: B |
|
1037.9 | 243.0 |
Annotations: CY |
|
1039.0 | 747.0 |
Annotations: Y Y |
|
1039.3 | 259.0 |
Annotations: Y Y |
|
1039.6 | 514.0 |
1039.9 | 452.0 |
1040.5 | 407.0 |
1040.8 | 434.0 |
1041.9 | 134.0 |
1049.4 | 345.0 |
Annotations: ZZ ZZ |
|
1049.5 | 389.0 |
Annotations: ZZ ZZ |
|
1049.9 | 1052.0 |
Annotations: YZ ZY |
|
1050.8 | 300.0 |
Annotations: YZ ZY |
|
1051.3 | 118.0 |
1053.5 | 194.0 |
Annotations: Y^{0,4}X_{Fuc} |
|
1058.4 | 328.0 |
Annotations: YZ ZY YZ ZY |
|
1058.9 | 560.0 |
Annotations: YY |
|
1059.4 | 115.0 |
Annotations: YY |
|
1060.3 | 158.0 |
1069.2 | 147.0 |
1072.8 | 434.0 |
Annotations: ^{1,5}X_{Gal}Z Z^{1,5}X_{Fuc} ^{1,5}X_{Gal}Z Z^{1,5}X_{Fuc} |
|
1076.3 | 108.0 |
Annotations: Y |
|
1077.0 | 625.0 |
1079.6 | 547.0 |
Annotations: ^{0,2}X_{Gal}Z Z^{0,2}X_{Fuc} ^{0,2}X_{Gal}Z Z^{0,2}X_{Fuc} ^{0,4}X_{NeuAc}Z ^{2,5}X_{Gal}Z Z^{2,5}X_{Gal} |
|
1087.4 | 207.0 |
Annotations: Z^{2,5}X_{Fuc} ^{2,5}X_{Gal}Z Z^{2,5}X_{Fuc} ^{2,5}X_{Gal}Z |
|
1092.9 | 110.0 |
1102.0 | 605.0 |
Annotations: ^{3,5}X_{Gal}Z Z^{3,5}X_{Fuc} ^{3,5}X_{Gal}Z Z^{3,5}X_{Fuc} |
|
1102.4 | 267.0 |
Annotations: ^{3,5}X_{Gal}Z Z^{3,5}X_{Fuc} ^{3,5}X_{Gal}Z Z^{3,5}X_{Fuc} |
|
1109.4 | 203.0 |
Annotations: ^{0,4}X_{Gal}Z ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{0,4}X_{Fuc} ^{0,4}X_{Gal}Z ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Z Z^{1,3}X_{NeuAc} |
|
1109.9 | 538.0 |
Annotations: ^{1,4}A_{Man}Y C^{0,3}X_{Gal} C^{1,4}X_{Gal} |
|
1110.5 | 1005.0 |
Annotations: ^{1,4}A_{Man}Y C^{0,3}X_{Gal} C^{1,4}X_{Gal} ^{2,4}X_{GlcNAc} ^{0,4}X_{Gal}Y ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{2,4}X_{GlcNAc} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{0,2}X_{NeuAc} |
|
1110.8 | 365.0 |
Annotations: ^{2,4}X_{GlcNAc} ^{1,4}A_{Man}Y C^{0,3}X_{Gal} C^{1,4}X_{Gal} ^{2,4}X_{GlcNAc} ^{0,4}X_{Gal}Y ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{0,2}X_{NeuAc} |
|
1111.0 | 586.0 |
Annotations: Y^{3,5}X_{Fuc} ^{0,2}X_{NeuAc} ^{3,5}X_{Gal}Y Y^{3,5}X_{Fuc} ^{3,5}X_{Gal}Y |
|
1111.5 | 319.0 |
Annotations: ^{3,5}X_{Gal}Y Y^{3,5}X_{Fuc} ^{3,5}X_{Gal}Y Y^{3,5}X_{Fuc} ^{1,5}X_{NeuAc} |
|
1111.9 | 216.0 |
Annotations: ^{1,5}X_{NeuAc} |
|
1113.5 | 118.0 |
1114.3 | 319.0 |
Annotations: YY |
|
1119.0 | 701.0 |
Annotations: ^{2,5}X_{NeuAc} |
|
1119.4 | 335.0 |
1119.9 | 246.0 |
1120.5 | 189.0 |
1120.7 | 245.0 |
1120.9 | 143.0 |
1122.9 | 410.0 |
Annotations: Z^{0,2}X_{Gal} |
|
1123.5 | 102.0 |
1131.4 | 1722.0 |
Annotations: Z Z |
|
1132.0 | 3584.0 |
1132.5 | 1061.0 |
1132.8 | 614.0 |
1133.5 | 135.0 |
Annotations: ^{3,5}X_{NeuAc} |
|
1134.4 | 125.0 |
1139.4 | 2117.0 |
Annotations: Z |
|
1140.0 | 1705.0 |
Annotations: Y Y |
|
1140.5 | 4739.0 |
Annotations: Y Y |
|
1141.0 | 3568.0 |
1141.3 | 1321.0 |
1141.5 | 1852.0 |
1141.8 | 721.0 |
1142.0 | 627.0 |
Annotations: Y^{1,5}X_{Fuc} |
|
1142.5 | 234.0 |
Annotations: Y^{1,5}X_{Fuc} |
|
1143.0 | 183.0 |
1148.4 | 695.0 |
Annotations: Y |
|
1149.0 | 997.0 |
1150.0 | 239.0 |
1155.4 | 259.0 |
Annotations: ^{0,2}A_{Man}Z |
|
1161.5 | 722.0 |
Annotations: ^{0,2}X_{Gal} ^{0,2}X_{Gal} ^{0,4}X_{NeuAc} |
|
1163.0 | 290.0 |
1163.5 | 473.0 |
Annotations: ^{1,4}X_{NeuAc} |
|
1168.0 | 741.0 |
Annotations: Z^{0,3}X_{Fuc} Z^{3,5}X_{Gal} |
|
1170.5 | 375.0 |
Annotations: ^{2,4}X_{NeuAc} Y^{1,4}X_{Fuc} Y^{0,3}X_{Gal} Y^{1,4}X_{Gal} |
|
1173.9 | 154.0 |
Annotations: ^{0,2}A_{Man}Y |
|
1182.3 | 105.0 |
Annotations: B |
|
1182.9 | 736.0 |
Annotations: B |
|
1191.0 | 237.0 |
Annotations: ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} |
|
1191.5 | 2578.0 |
Annotations: ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} |
|
1191.9 | 2502.0 |
Annotations: ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} |
|
1192.5 | 1778.0 |
Annotations: ^{3,5}X_{Fuc} |
|
1192.9 | 476.0 |
Annotations: ^{3,5}X_{Fuc} |
|
1200.5 | 2170.0 |
Annotations: C |
|
1200.9 | 1797.0 |
Annotations: C |
|
1201.5 | 1278.0 |
1202.0 | 368.0 |
Annotations: Y^{3,5}X_{Fuc} |
|
1203.0 | 182.0 |
1203.2 | 270.0 |
1203.5 | 267.0 |
1203.9 | 364.0 |
1212.0 | 520.0 |
1212.5 | 1980.0 |
1212.9 | 513.0 |
1213.5 | 1224.0 |
1213.9 | 196.0 |
1214.3 | 372.0 |
1218.5 | 110.0 |
1220.5 | 1054.0 |
1220.7 | 191.0 |
1220.9 | 169.0 |
1221.5 | 1775.0 |
Annotations: |
|
1242.3 | 108.0 |
Annotations: Z |
|
1245.1 | 123.0 |
1245.5 | 104.0 |
1260.7 | 180.0 |
Annotations: Y |
|
1262.6 | 258.0 |
1344.6 | 411.0 |
Annotations: BY CZ |
|
1345.0 | 170.0 |
1345.5 | 172.0 |
1346.5 | 408.0 |
Annotations: ^{1,4}A_{GlcNAc}Y C^{0,3}X_{GlcNAc} |
|
1349.5 | 145.0 |
1386.9 | 112.0 |
Annotations: ZZ ZZ |
|
1392.6 | 161.0 |
1447.4 | 282.0 |
1478.4 | 152.0 |
Annotations: ^{2,4}A_{GlcNAc}Y ^{1,5}A_{Man}Y ^{1,5}A_{Man}Y |
|
1493.6 | 517.0 |
1526.6 | 251.0 |
1583.8 | 121.0 |
1590.7 | 173.0 |
1591.8 | 366.0 |
1630.0 | 133.0 |
1643.8 | 263.0 |
1709.5 | 511.0 |
Annotations: CZ BY BY CZ BY BY CZ CZ |
|
1710.6 | 321.0 |
1711.7 | 221.0 |
Annotations: ^{1,4}A_{GlcNAc}Y ^{2,5}X_{NeuAc}Y Z^{3,5}X_{Fuc} |
|
1728.6 | 190.0 |
1747.5 | 169.0 |
1751.5 | 141.0 |
Annotations: ZZ ZZ |
|
1767.0 | 373.0 |
Annotations: ^{2,4}X_{GlcNAc}Z |
|
1787.6 | 231.0 |
Annotations: Y |
|
1788.8 | 338.0 |
Annotations: C^{2,4}X_{NeuAc} |
|
1829.8 | 103.0 |
Annotations: C^{0,4}X_{Gal} C^{1,3}X_{Gal} C^{2,4}X_{Gal} ^{0,2}A_{GlcNAc}Y ^{0,2}A_{GlcNAc}Y C^{0,4}X_{Gal} C^{1,3}X_{Gal} C^{2,4}X_{Gal} ^{0,2}A_{Man} |
|
1844.7 | 227.0 |
Annotations: YY |
|
1871.6 | 330.0 |
Annotations: B |
|
1872.8 | 331.0 |
Annotations: ^{1,3}X_{Man}Y Y^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Y Y^{1,5}X_{Fuc} |
|
1873.5 | 222.0 |
Annotations: C^{1,5}X_{NeuAc} ^{2,5}X_{NeuAc}Y Y^{2,5}X_{NeuAc} |
|
1889.7 | 1060.0 |
Annotations: C |
|
1890.0 | 571.0 |
Annotations: C |
|
1890.7 | 1167.0 |
1890.9 | 897.0 |
1891.8 | 264.0 |
1895.6 | 169.0 |
1912.7 | 419.0 |
Annotations: BY BY CZ CZ |
|
1914.0 | 231.0 |
1914.3 | 337.0 |
Annotations: YZ ZY YZ ZY |
|
1917.0 | 183.0 |
Annotations: Y |
|
1932.6 | 260.0 |
Annotations: YY YY |
|
1932.8 | 270.0 |
Annotations: YY YY |
|
1942.7 | 185.0 |
Annotations: ^{1,5}X_{GlcNAc}Z ^{1,5}X_{GlcNAc}Z Z^{1,5}X_{Fuc} Z^{1,5}X_{Fuc} |
|
1973.8 | 537.0 |
Annotations: B^{2,4}X_{NeuAc} |
|
1974.8 | 165.0 |
Annotations: Y^{0,2}X_{Fuc} Y^{0,2}X_{Fuc} ^{2,5}X_{Gal}Y Y^{2,5}X_{Gal} |
|
1990.9 | 189.0 |
Annotations: Y |
|
1991.1 | 323.0 |
Annotations: Y |
|
1991.9 | 321.0 |
Annotations: C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc} |
|
1992.1 | 194.0 |
Annotations: C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc} |
|
1992.9 | 187.0 |
2015.7 | 220.0 |
Annotations: ^{0,2}X_{GlcNAc}Y ^{0,2}X_{GlcNAc}Y Y^{2,5}X_{GlcNAc} ^{2,5}X_{GlcNAc}Y |
|
2020.7 | 275.0 |
Annotations: Y^{3,5}X_{Fuc} Y^{3,5}X_{Fuc} |
|
2021.9 | 188.0 |
2037.9 | 150.0 |
2058.6 | 194.0 |
Annotations: Z^{2,5}X_{NeuAc} ^{0,2}X_{NeuAc}Z ^{2,5}X_{NeuAc}Z |
|
2061.7 | 276.0 |
Annotations: ^{3,5}X_{GlcNAc}Y ^{3,5}X_{GlcNAc}Y |
|
2063.6 | 143.0 |
2074.8 | 433.0 |
Annotations: B |
|
2075.8 | 192.0 |
Annotations: ^{2,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y |
|
2076.0 | 354.0 |
Annotations: ^{2,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y |
|
2076.6 | 385.0 |
Annotations: ^{0,2}X_{NeuAc}Y ^{2,5}X_{NeuAc}Y Y^{2,5}X_{NeuAc} Z^{3,5}X_{Fuc} |
|
2078.8 | 112.0 |
Annotations: Y Y |
|
2080.0 | 213.0 |
2092.8 | 291.0 |
Annotations: C |
|
2093.1 | 261.0 |
Annotations: C |
|
2093.6 | 172.0 |
2094.9 | 413.0 |
Annotations: Y^{3,5}X_{Fuc} |
|
2110.9 | 164.0 |
2136.0 | 187.0 |
Annotations: YY YY |
|
2139.0 | 388.0 |
2142.8 | 354.0 |
2151.7 | 157.0 |
2152.5 | 189.0 |
Annotations: Y |
|
2152.8 | 483.0 |
Annotations: Y |
|
2153.8 | 987.0 |
2154.1 | 216.0 |
2154.8 | 376.0 |
2155.3 | 171.0 |
2156.8 | 492.0 |