In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.
GlyToucan Accession Number: G13249MW
Peak | Intensity |
---|---|
424.1 | 228.0 |
Annotations: ^{1,3}A_{Man} ^{0,4}A_{Man}Y C^{0,2}X_{Gal} |
|
553.3 | 158.0 |
Annotations: Z |
|
655.3 | 317.0 |
Annotations: B |
|
673.3 | 103.0 |
Annotations: C |
|
804.4 | 123.0 |
Annotations: ^{2,5}A_{GlcNAc}Y ^{2,5}A_{GlcNAc}Y |
|
875.9 | 483.0 |
Annotations: YZ ZY |
|
884.3 | 160.0 |
Annotations: Z |
|
886.0 | 104.0 |
911.8 | 193.0 |
Annotations: ^{1,4}X_{Man}Z Z^{0,3}X_{Fuc} ^{3,5}X_{Gal}Z ^{3,5}X_{GlcNAc}Z Z^{3,5}X_{GlcNAc} |
|
915.9 | 112.0 |
Annotations: B^{2,5}X_{GlcNAc} |
|
926.8 | 201.0 |
Annotations: B^{0,2}X_{NeuAc} ^{1,3}X_{Man}Z Z^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Z Z^{1,5}X_{Fuc} |
|
936.8 | 137.0 |
Annotations: C^{1,5}X_{NeuAc} ^{2,5}X_{NeuAc}Y ^{2,5}X_{NeuAc}Y |
|
944.9 | 279.0 |
948.3 | 178.0 |
Annotations: ZZ ZZ |
|
949.5 | 111.0 |
Annotations: Z^{1,4}X_{GlcNAc} B^{3,5}X_{NeuAc} Y^{1,4}X_{Fuc} Y^{0,3}X_{GlcNAc} Y^{0,3}X_{Gal} Y^{1,4}X_{Gal} ^{0,3}X_{GlcNAc} Y^{0,3}X_{Gal} Y^{1,4}X_{Gal} Y^{0,3}X_{GlcNAc} |
|
951.8 | 177.0 |
Annotations: ^{1,3}A_{Man}Y ^{2,4}A_{Man}Y ^{3,5}X_{NeuAc}Y ^{3,5}X_{NeuAc}Y |
|
956.9 | 232.0 |
Annotations: YZ ZY YZ ZY |
|
957.8 | 193.0 |
Annotations: Y |
|
965.3 | 1809.0 |
Annotations: CY CY |
|
965.9 | 1788.0 |
Annotations: YY YY |
|
966.4 | 758.0 |
966.7 | 275.0 |
966.9 | 156.0 |
Annotations: Y^{1,4}X_{GlcNAc} |
|
977.3 | 265.0 |
Annotations: ZZ ZZ |
|
978.5 | 150.0 |
Annotations: C^{2,4}X_{GlcNAc} Y^{0,2}X_{GlcNAc} C^{1,5}X_{Gal} C^{1,5}X_{Gal} ^{0,4}X_{NeuAc}Y ^{0,2}X_{Gal}Y Y^{0,2}X_{Gal} ^{0,4}X_{NeuAc}Y |
|
985.9 | 136.0 |
Annotations: Z |
|
1002.4 | 187.0 |
Annotations: BZ YY |
|
1008.9 | 167.0 |
Annotations: C^{3,5}X_{Gal} C^{3,5}X_{Gal} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{1,5}X_{Gal} Y^{1,5}X_{Gal} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{1,3}X_{Man} ^{0,4}X_{Gal}Y ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} C^{0,3}X_{NeuAc} |
|
1009.3 | 198.0 |
Annotations: C^{3,5}X_{Gal} Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} C^{0,3}X_{NeuAc} C^{3,5}X_{Gal} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{1,5}X_{Gal} Y^{1,5}X_{Gal} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{1,3}X_{Man} ^{0,4}X_{Gal}Y ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y |
|
1010.3 | 259.0 |
Annotations: Y^{3,5}X_{Fuc} Y^{3,5}X_{Fuc} |
|
1017.8 | 228.0 |
1018.4 | 351.0 |
1020.5 | 141.0 |
Annotations: BY CZ |
|
1021.5 | 189.0 |
Annotations: ^{3,5}X_{GlcNAc}Z ^{3,5}X_{GlcNAc}Z ^{1,5}X_{NeuAc}Z ^{1,5}X_{NeuAc}Z Z^{1,4}X_{Fuc} Z^{0,3}X_{Gal} Z^{1,4}X_{Gal} Z^{0,3}X_{Gal} Z^{1,4}X_{Gal} |
|
1021.8 | 228.0 |
Annotations: ^{3,5}X_{GlcNAc}Z ^{3,5}X_{GlcNAc}Z ^{1,5}X_{NeuAc}Z ^{1,5}X_{NeuAc}Z Z^{1,4}X_{Fuc} Z^{0,3}X_{Gal} Z^{1,4}X_{Gal} Z^{0,3}X_{Gal} Z^{1,4}X_{Gal} |
|
1028.5 | 285.0 |
Annotations: ^{2,4}X_{GlcNAc}Z ^{0,2}X_{NeuAc}Z ^{2,5}X_{NeuAc}Z ^{2,5}X_{NeuAc}Z ^{2,4}X_{GlcNAc}Z |
|
1028.8 | 235.0 |
Annotations: ^{2,4}X_{GlcNAc}Z ^{2,4}X_{GlcNAc}Z ^{0,2}X_{NeuAc}Z ^{2,5}X_{NeuAc}Z ^{2,5}X_{NeuAc}Z |
|
1030.4 | 219.0 |
Annotations: ^{3,5}X_{GlcNAc}Y ^{3,5}X_{GlcNAc}Y ^{1,5}X_{NeuAc}Y ^{1,5}X_{NeuAc}Y Y^{1,4}X_{Fuc} Y^{0,3}X_{Gal} Y^{1,4}X_{Gal} Y^{0,3}X_{Gal} Y^{1,4}X_{Gal} |
|
1036.9 | 511.0 |
Annotations: B |
|
1038.4 | 180.0 |
Annotations: Y Y |
|
1038.8 | 167.0 |
Annotations: Y Y |
|
1039.0 | 336.0 |
Annotations: Y Y |
|
1039.4 | 275.0 |
1039.9 | 447.0 |
1040.4 | 285.0 |
1049.3 | 472.0 |
Annotations: ZZ ZZ |
|
1050.0 | 380.0 |
Annotations: YZ ZY |
|
1050.5 | 198.0 |
Annotations: YZ ZY |
|
1050.9 | 109.0 |
1053.4 | 177.0 |
Annotations: Y^{0,4}X_{Fuc} |
|
1054.3 | 172.0 |
Annotations: Y^{0,4}X_{Fuc} |
|
1058.4 | 384.0 |
Annotations: YZ ZY YZ ZY |
|
1059.0 | 897.0 |
Annotations: YY |
|
1059.9 | 186.0 |
1074.4 | 264.0 |
Annotations: ^{1,4}X_{GlcNAc} ^{1,4}X_{GlcNAc} |
|
1074.9 | 125.0 |
Annotations: ^{1,4}X_{GlcNAc} ^{1,4}X_{GlcNAc} |
|
1079.8 | 187.0 |
Annotations: ^{0,2}X_{Gal}Z Z^{0,2}X_{Fuc} ^{0,4}X_{NeuAc}Z ^{0,2}X_{Gal}Z Z^{0,2}X_{Fuc} ^{2,5}X_{Gal}Z Z^{2,5}X_{Gal} |
|
1089.8 | 162.0 |
Annotations: ^{2,4}X_{NeuAc}Y ^{2,4}X_{NeuAc}Y |
|
1093.8 | 380.0 |
1099.3 | 289.0 |
Annotations: C^{2,4}X_{NeuAc} |
|
1101.3 | 131.0 |
Annotations: Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} ^{0,4}X_{Gal}Z ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} Z^{0,4}X_{Gal} Z^{1,3}X_{Gal} Z^{2,4}X_{Gal} |
|
1109.4 | 521.0 |
Annotations: ^{0,4}X_{Gal}Z ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{0,4}X_{Fuc} ^{0,4}X_{Gal}Z ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Z ^{1,3}X_{NeuAc}Z |
|
1109.8 | 602.0 |
Annotations: ^{0,4}X_{Gal}Z ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{0,4}X_{Fuc} ^{0,4}X_{Gal}Z ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Z ^{1,3}X_{NeuAc}Z |
|
1110.4 | 693.0 |
Annotations: C^{1,4}X_{Gal} ^{2,4}X_{GlcNAc} ^{0,4}X_{Gal}Y ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{2,4}X_{GlcNAc} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{0,2}X_{NeuAc} ^{1,4}A_{Man}Y C^{0,3}X_{Gal} |
|
1111.0 | 371.0 |
Annotations: ^{0,2}X_{NeuAc} ^{3,5}X_{Gal}Y Y^{3,5}X_{Fuc} ^{3,5}X_{Gal}Y Y^{3,5}X_{Fuc} |
|
1111.4 | 645.0 |
Annotations: ^{3,5}X_{Gal}Y Y^{3,5}X_{Fuc} ^{3,5}X_{Gal}Y Y^{3,5}X_{Fuc} ^{1,5}X_{NeuAc} |
|
1118.4 | 284.0 |
Annotations: ^{0,4}X_{Gal}Y ^{2,4}X_{Gal}Y Y^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Y ^{0,4}X_{Gal}Y ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y Y^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Y ^{2,5}X_{NeuAc} ^{1,3}X_{Gal}Y |
|
1119.0 | 410.0 |
Annotations: ^{2,5}X_{NeuAc} |
|
1119.5 | 168.0 |
1120.0 | 769.0 |
1120.3 | 347.0 |
1122.4 | 292.0 |
Annotations: B^{0,4}X_{Gal} B^{1,3}X_{Gal} B^{2,4}X_{Gal} Z^{0,2}X_{Gal} |
|
1130.4 | 127.0 |
1131.4 | 384.0 |
Annotations: Z Z |
|
1132.0 | 1084.0 |
1132.4 | 397.0 |
1133.0 | 417.0 |
1133.4 | 220.0 |
Annotations: ^{3,5}X_{NeuAc} |
|
1133.9 | 113.0 |
Annotations: ^{3,5}X_{NeuAc} |
|
1139.4 | 2497.0 |
Annotations: Z |
|
1139.9 | 1676.0 |
Annotations: Z |
|
1140.4 | 3048.0 |
Annotations: Y Y |
|
1140.9 | 1859.0 |
Annotations: Y Y |
|
1141.5 | 1836.0 |
1142.0 | 413.0 |
Annotations: Y^{1,5}X_{Fuc} |
|
1142.5 | 248.0 |
Annotations: Y^{1,5}X_{Fuc} |
|
1148.9 | 337.0 |
Annotations: Y |
|
1155.5 | 120.0 |
Annotations: ^{0,2}A_{Man}Z |
|
1156.5 | 149.0 |
Annotations: Y^{2,5}X_{Gal} C^{1,3}X_{NeuAc} Y^{0,2}X_{Fuc} |
|
1159.5 | 117.0 |
1161.5 | 258.0 |
Annotations: ^{0,2}X_{Gal} ^{0,4}X_{NeuAc} ^{0,2}X_{Gal} |
|
1167.0 | 154.0 |
1170.0 | 116.0 |
Annotations: Y^{1,4}X_{Fuc} Y^{0,3}X_{Gal} Y^{1,4}X_{Gal} |
|
1170.5 | 196.0 |
Annotations: Y^{1,4}X_{Fuc} Y^{0,3}X_{Gal} Y^{1,4}X_{Gal} ^{2,4}X_{NeuAc} |
|
1171.5 | 373.0 |
1173.9 | 209.0 |
Annotations: ^{0,2}A_{Man}Y |
|
1180.5 | 113.0 |
1182.4 | 152.0 |
Annotations: B |
|
1184.4 | 143.0 |
Annotations: ^{0,3}X_{Fuc} ^{3,5}X_{Gal} ^{3,5}X_{Gal} Z^{3,5}X_{Fuc} |
|
1184.9 | 122.0 |
Annotations: ^{0,3}X_{Fuc} ^{3,5}X_{Gal} ^{3,5}X_{Gal} Z^{3,5}X_{Fuc} |
|
1191.5 | 1602.0 |
Annotations: ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} |
|
1191.9 | 1601.0 |
Annotations: ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} |
|
1192.4 | 485.0 |
Annotations: ^{3,5}X_{Fuc} |
|
1192.9 | 314.0 |
Annotations: ^{3,5}X_{Fuc} |
|
1194.1 | 136.0 |
1194.7 | 157.0 |
1200.5 | 3836.0 |
Annotations: C |
|
1201.0 | 1905.0 |
1201.5 | 2550.0 |
1201.8 | 572.0 |
1202.1 | 525.0 |
Annotations: Y^{3,5}X_{Fuc} |
|
1202.4 | 697.0 |
Annotations: Y^{3,5}X_{Fuc} |
|
1203.0 | 110.0 |
1203.4 | 202.0 |
1212.0 | 207.0 |
1212.4 | 673.0 |
1213.0 | 198.0 |
1220.4 | 115.0 |
1221.0 | 354.0 |
Annotations: |
|
1221.5 | 1046.0 |
Annotations: |
|
1242.5 | 305.0 |
Annotations: Z |
|
1243.5 | 123.0 |
Annotations: B^{1,5}X_{GlcNAc} |
|
1261.4 | 120.0 |
Annotations: C^{1,5}X_{GlcNAc} |
|
1369.5 | 214.0 |
1566.8 | 207.0 |
Annotations: ^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y |
|
1571.5 | 178.0 |
1690.5 | 172.0 |
Annotations: ^{0,2}X_{GlcNAc}Z Z^{0,2}X_{GlcNAc} Z^{0,2}X_{GlcNAc} ^{0,2}X_{GlcNAc}Z |
|
1727.6 | 185.0 |
Annotations: CY CY CY CY |
|
1728.7 | 375.0 |
1787.5 | 189.0 |
Annotations: Y |
|
1789.7 | 108.0 |
1811.6 | 181.0 |
Annotations: ^{0,2}A_{GlcNAc}Z ^{0,2}A_{GlcNAc}Z B^{0,4}X_{Gal} B^{1,3}X_{Gal} B^{2,4}X_{Gal} B^{0,4}X_{Gal} B^{1,3}X_{Gal} B^{2,4}X_{Gal} |
|
1829.7 | 110.0 |
Annotations: ^{0,2}A_{GlcNAc}Y ^{0,2}A_{GlcNAc}Y C^{0,4}X_{Gal} C^{1,3}X_{Gal} C^{2,4}X_{Gal} C^{0,4}X_{Gal} C^{1,3}X_{Gal} C^{2,4}X_{Gal} ^{0,2}A_{Man} |
|
1871.6 | 217.0 |
Annotations: B |
|
1872.8 | 163.0 |
Annotations: ^{1,3}X_{Man}Y Y^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Y Y^{1,5}X_{Fuc} |
|
1889.7 | 685.0 |
Annotations: C |
|
1890.7 | 922.0 |
1891.7 | 268.0 |
1892.7 | 179.0 |
1915.5 | 149.0 |
1972.8 | 240.0 |
Annotations: Z |
|
1974.0 | 144.0 |
Annotations: B^{2,4}X_{NeuAc} |
|
2061.9 | 177.0 |
Annotations: ^{3,5}X_{GlcNAc}Y ^{3,5}X_{GlcNAc}Y |
|
2062.8 | 112.0 |
Annotations: Y^{0,3}X_{Gal} Y^{1,4}X_{Gal} ^{1,5}X_{NeuAc}Y ^{1,5}X_{NeuAc}Y Y^{1,4}X_{Fuc} Y^{0,3}X_{Gal} Y^{1,4}X_{Gal} |
|
2064.8 | 138.0 |
Annotations: Y^{2,5}X_{Fuc} |
|
2074.7 | 278.0 |
Annotations: B |
|
2079.7 | 133.0 |
2092.8 | 139.0 |
Annotations: C |
|
2149.8 | 138.0 |
2152.8 | 267.0 |
Annotations: Y |
|
2153.8 | 115.0 |
2155.8 | 134.0 |