In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.
GlyToucan Accession Number: G46031NV
Peak | Intensity |
---|---|
350.1 | 186.0 |
Annotations: Z |
|
350.3 | 109.0 |
Annotations: Z |
|
351.4 | 101.0 |
Annotations: B^{2,4}X_{NeuAc} ^{3,5}X_{GlcNAc}Y |
|
368.1 | 175.0 |
Annotations: Y |
|
382.0 | 147.0 |
Annotations: C |
|
407.3 | 104.0 |
Annotations: YZ ZY |
|
424.1 | 382.0 |
Annotations: C^{0,2}X_{Gal} C^{0,2}X_{Gal} ^{1,5}A_{Gal} ^{1,3}A_{Man} ^{1,3}A_{Man}Y ^{0,4}A_{Man}Y ^{1,3}A_{Man}Y ^{2,4}A_{Man}Y |
|
554.1 | 170.0 |
Annotations: ^{1,5}X_{Gal}Z Z^{1,5}X_{Man} ^{1,5}X_{Man}Z Z^{1,5}X_{Gal} B^{2,4}X_{NeuAc} ^{3,5}A_{GlcNAc}Z |
|
571.2 | 224.0 |
Annotations: Y |
|
586.3 | 123.0 |
Annotations: ^{0,2}A_{Man}Y ^{0,4}A_{Man} ^{1,3}A_{Man}Y ^{2,4}A_{Man}Y ^{0,2}A_{GlcNAc}Y C^{0,4}X_{Gal} |
|
621.1 | 139.0 |
Annotations: Z |
|
655.2 | 646.0 |
Annotations: B |
|
656.2 | 223.0 |
Annotations: ^{0,2}X_{NeuAc}Z |
|
670.0 | 108.0 |
Annotations: BZ |
|
672.3 | 154.0 |
Annotations: ^{1,4}A_{GlcNAc}Y C^{0,3}X_{Gal} ^{2,5}X_{NeuAc}Y Z^{3,5}X_{Fuc} |
|
688.1 | 200.0 |
Annotations: BY CZ |
|
692.3 | 233.0 |
Annotations: ZZ |
|
692.7 | 255.0 |
Annotations: ZZ |
|
701.9 | 441.0 |
Annotations: Z |
|
702.3 | 137.0 |
Annotations: YY |
|
708.7 | 147.0 |
Annotations: BY CZ |
|
731.4 | 132.0 |
Annotations: YY |
|
738.0 | 130.0 |
Annotations: ^{1,5}X_{NeuAc}Z Z^{1,4}X_{GlcNAc} ^{1,4}X_{Man}Y Y^{0,3}X_{Fuc} |
|
753.3 | 166.0 |
Annotations: ^{1,5}X_{Gal}Y ^{1,3}X_{Man}Y Y^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Y Y^{1,5}X_{Fuc} C^{1,5}X_{NeuAc} ^{2,5}X_{NeuAc}Y |
|
753.8 | 112.0 |
Annotations: C^{1,5}X_{NeuAc} ^{2,5}X_{NeuAc}Y |
|
774.8 | 135.0 |
Annotations: Y |
|
775.3 | 107.0 |
Annotations: Y |
|
782.8 | 2478.0 |
Annotations: YY |
|
783.3 | 1045.0 |
Annotations: YY |
|
783.7 | 966.0 |
Annotations: YY |
|
786.3 | 185.0 |
786.6 | 124.0 |
797.4 | 136.0 |
Annotations: Y^{1,5}X_{Fuc} ^{0,3}A_{GlcNAc} ^{1,5}X_{GlcNAc}Y |
|
799.4 | 143.0 |
804.0 | 147.0 |
Annotations: B^{2,4}X_{NeuAc} ^{1,5}A_{Man}Z Y^{0,2}X_{Fuc} |
|
813.4 | 100.0 |
817.3 | 879.0 |
Annotations: B |
|
818.4 | 519.0 |
Annotations: ^{1,4}A_{GlcNAc} C^{0,3}X_{Gal} C^{1,4}X_{Gal} Z^{3,5}X_{Fuc} |
|
819.3 | 151.0 |
Annotations: ^{1,4}A_{GlcNAc}Y ^{1,4}X_{GlcNAc}Y Y^{0,3}X_{Fuc} |
|
826.5 | 160.0 |
Annotations: C^{3,5}X_{Gal} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{1,5}X_{Gal} ^{1,5}X_{Gal} ^{1,3}X_{Man} |
|
831.3 | 176.0 |
835.3 | 1848.0 |
Annotations: C |
|
836.2 | 678.0 |
837.1 | 218.0 |
837.4 | 221.0 |
838.1 | 114.0 |
Annotations: ^{0,2}X_{NeuAc}Z |
|
845.8 | 444.0 |
Annotations: ^{1,5}A_{GlcNAc}Z ^{2,4}X_{GlcNAc}Z ^{0,2}X_{NeuAc}Z ^{2,5}X_{NeuAc}Z |
|
846.4 | 313.0 |
Annotations: ^{0,2}X_{NeuAc}Z ^{2,5}X_{NeuAc}Z |
|
847.3 | 236.0 |
Annotations: Z |
|
851.8 | 206.0 |
855.4 | 318.0 |
Annotations: ^{0,2}X_{NeuAc}Y ^{2,5}X_{NeuAc}Y Z^{3,5}X_{Fuc} |
|
855.8 | 139.0 |
Annotations: ^{1,5}X_{NeuAc}Y |
|
856.3 | 268.0 |
Annotations: Y |
|
856.7 | 171.0 |
Annotations: Y |
|
856.9 | 266.0 |
859.4 | 121.0 |
Annotations: ZZ ZZ |
|
867.3 | 314.0 |
Annotations: ZZ |
|
868.3 | 140.0 |
Annotations: CY |
|
875.9 | 805.0 |
Annotations: YZ ZY |
|
876.2 | 174.0 |
Annotations: YZ ZY |
|
876.8 | 338.0 |
Annotations: ^{1,3}A_{Man} ^{2,4}A_{Man} |
|
877.3 | 125.0 |
Annotations: YZ ZY YZ ZY |
|
878.4 | 168.0 |
Annotations: B^{1,5}X_{GlcNAc} ^{3,5}X_{NeuAc}Y |
|
885.9 | 248.0 |
891.3 | 227.0 |
Annotations: BY CZ |
|
895.3 | 184.0 |
Annotations: YY YY |
|
901.2 | 168.0 |
905.8 | 373.0 |
Annotations: ^{1,5}X_{GlcNAc}Z Z^{1,5}X_{Man} ^{1,5}X_{Man}Z Z^{1,5}X_{GlcNAc} ^{0,2}X_{Gal}Y Y^{0,2}X_{Fuc} ^{0,4}X_{NeuAc}Y ^{2,5}X_{GlcNAc} |
|
908.9 | 170.0 |
Annotations: CY |
|
911.2 | 109.0 |
915.3 | 283.0 |
Annotations: ^{2,4}X_{NeuAc}Y |
|
926.9 | 358.0 |
Annotations: ^{1,3}X_{NeuAc}Z ^{0,4}X_{Gal}Z ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{0,4}X_{Fuc} |
|
927.5 | 485.0 |
Annotations: Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{2,4}X_{GlcNAc} |
|
927.9 | 232.0 |
Annotations: Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{2,4}X_{GlcNAc} ^{0,2}X_{NeuAc} |
|
928.3 | 465.0 |
Annotations: Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{2,4}X_{GlcNAc} ^{0,2}X_{NeuAc} |
|
929.5 | 137.0 |
Annotations: ^{1,5}X_{NeuAc} |
|
936.4 | 618.0 |
Annotations: ^{2,5}A_{GlcNAc}Z ^{2,5}X_{NeuAc} |
|
936.9 | 410.0 |
Annotations: C^{1,5}X_{Man} |
|
937.2 | 150.0 |
Annotations: C^{1,5}X_{Man} |
|
937.5 | 289.0 |
Annotations: C^{1,5}X_{Man} |
|
939.6 | 179.0 |
948.8 | 844.0 |
Annotations: Z |
|
949.4 | 839.0 |
Annotations: B^{2,5}X_{GlcNAc} ^{1,4}X_{GlcNAc}Z Z^{1,4}X_{Man} ^{1,4}X_{Man}Z Z^{1,4}X_{GlcNAc} |
|
949.7 | 149.0 |
Annotations: B^{2,5}X_{GlcNAc} ^{1,4}X_{GlcNAc}Z Z^{1,4}X_{Man} ^{1,4}X_{Man}Z Z^{1,4}X_{GlcNAc} |
|
950.2 | 151.0 |
956.4 | 137.0 |
Annotations: Z |
|
956.9 | 2057.0 |
Annotations: Z |
|
957.4 | 2614.0 |
Annotations: Y |
|
957.8 | 1355.0 |
Annotations: Y |
|
958.4 | 695.0 |
958.9 | 692.0 |
965.9 | 110.0 |
Annotations: Y |
|
967.0 | 128.0 |
Annotations: C^{2,5}X_{GlcNAc} ^{1,4}X_{GlcNAc}Y Y^{1,4}X_{Man} ^{1,4}X_{Man}Y Y^{1,4}X_{GlcNAc} |
|
972.3 | 112.0 |
Annotations: ^{1,5}X_{Gal} |
|
972.8 | 201.0 |
978.5 | 284.0 |
Annotations: ^{0,2}X_{GlcNAc}Y Y^{0,2}X_{GlcNAc} ^{0,2}X_{Gal} ^{0,4}X_{NeuAc} |
|
978.8 | 194.0 |
Annotations: ^{0,2}X_{GlcNAc}Y Y^{0,2}X_{GlcNAc} ^{0,2}X_{Gal} ^{0,4}X_{NeuAc} |
|
979.4 | 300.0 |
Annotations: BY CZ |
|
988.4 | 148.0 |
Annotations: ^{2,4}X_{NeuAc} |
|
988.7 | 105.0 |
Annotations: ^{2,4}X_{NeuAc} |
|
989.3 | 211.0 |
997.4 | 198.0 |
Annotations: CY |
|
1001.3 | 410.0 |
1003.8 | 126.0 |
1004.4 | 126.0 |
1006.2 | 105.0 |
Annotations: ^{3,5}X_{GlcNAc}Z Z^{3,5}X_{GlcNAc} |
|
1008.9 | 1739.0 |
Annotations: ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} |
|
1009.3 | 930.0 |
Annotations: ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} |
|
1009.9 | 646.0 |
Annotations: ^{3,5}X_{Fuc} |
|
1010.4 | 125.0 |
1010.7 | 140.0 |
1017.9 | 1933.0 |
1018.3 | 952.0 |
1018.9 | 988.0 |
1019.4 | 438.0 |
1019.8 | 165.0 |
1020.3 | 123.0 |
Annotations: ^{2,4}X_{GlcNAc}Z Z^{2,4}X_{GlcNAc} |
|
1021.2 | 407.0 |
Annotations: ZZ |
|
1028.9 | 486.0 |
1029.3 | 355.0 |
1030.1 | 149.0 |
1030.4 | 475.0 |
1032.0 | 107.0 |
1057.3 | 100.0 |
Annotations: YY |
|
1095.4 | 207.0 |
Annotations: ^{2,4}A_{GlcNAc}Z B^{0,2}X_{Gal} ^{1,5}A_{Man}Z |
|
1097.5 | 110.0 |
1100.4 | 147.0 |
1161.3 | 106.0 |
1201.6 | 140.0 |
Annotations: ^{2,4}A_{GlcNAc}Y |
|
1202.4 | 109.0 |
Annotations: Y^{3,5}X_{Fuc} |
|
1218.7 | 107.0 |
1225.6 | 247.0 |
1260.6 | 129.0 |
Annotations: Y |
|
1276.5 | 189.0 |
Annotations: YY |
|
1362.5 | 292.0 |
Annotations: CY CY |
|
1363.5 | 129.0 |
1380.5 | 149.0 |
1380.8 | 125.0 |
1384.6 | 116.0 |
1404.6 | 127.0 |
Annotations: Z |
|
1418.5 | 110.0 |
Annotations: BY CZ |
|
1422.6 | 103.0 |
Annotations: Y |
|
1425.9 | 123.0 |
1445.8 | 118.0 |
Annotations: YZ ZY |
|
1449.4 | 213.0 |
1461.6 | 110.0 |
Annotations: YZ ZY |
|
1465.6 | 236.0 |
1469.2 | 201.0 |
1505.6 | 125.0 |
Annotations: C^{2,4}X_{GlcNAc} Y^{0,2}X_{GlcNAc} Y^{0,2}X_{Gal} ^{0,2}X_{GlcNAc} ^{0,2}X_{Gal}Y |
|
1505.7 | 104.0 |
Annotations: C^{2,4}X_{GlcNAc} Y^{0,2}X_{GlcNAc} Y^{0,2}X_{Gal} ^{0,2}X_{GlcNAc} ^{0,2}X_{Gal}Y |
|
1506.5 | 309.0 |
Annotations: B |
|
1507.5 | 137.0 |
Annotations: Y^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Y Y^{1,5}X_{Fuc} ^{1,5}X_{Gal}Y ^{1,3}X_{Man}Y |
|
1507.6 | 139.0 |
Annotations: ^{1,5}X_{Gal}Y ^{1,3}X_{Man}Y Y^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Y Y^{1,5}X_{Fuc} |
|
1508.5 | 106.0 |
Annotations: C^{1,5}X_{NeuAc} ^{2,5}X_{NeuAc}Y |
|
1524.7 | 659.0 |
Annotations: C |
|
1525.6 | 825.0 |
1526.7 | 182.0 |
1527.7 | 129.0 |
1529.6 | 122.0 |
Annotations: BZ |
|
1533.6 | 107.0 |
Annotations: Z |
|
1547.5 | 259.0 |
Annotations: BY CZ |
|
1548.5 | 274.0 |
1549.6 | 272.0 |
Annotations: YZ ZY |
|
1551.2 | 105.0 |
Annotations: Y |
|
1566.5 | 157.0 |
Annotations: ^{2,4}A_{GlcNAc} |
|
1567.6 | 109.0 |
Annotations: YY |
|
1607.5 | 222.0 |
Annotations: Z |
|
1610.6 | 257.0 |
Annotations: ^{2,5}A_{GlcNAc} |
|
1612.9 | 130.0 |
Annotations: C^{1,4}X_{NeuAc} ^{2,4}X_{NeuAc}Y |
|
1624.7 | 122.0 |
1625.7 | 187.0 |
Annotations: Y |
|
1626.5 | 391.0 |
Annotations: C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc} |
|
1626.7 | 368.0 |
Annotations: C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc} |
|
1627.1 | 212.0 |
1627.7 | 185.0 |
1628.7 | 126.0 |
1654.7 | 154.0 |
1670.6 | 125.0 |
1691.7 | 148.0 |
1693.7 | 334.0 |
Annotations: ^{0,2}X_{NeuAc}Z ^{2,5}X_{NeuAc}Z |
|
1709.7 | 881.0 |
Annotations: B |
|
1710.7 | 574.0 |
Annotations: ^{2,4}X_{GlcNAc}Y |
|
1711.6 | 439.0 |
Annotations: ^{0,2}X_{NeuAc}Y ^{2,5}X_{NeuAc}Y Z^{3,5}X_{Fuc} |
|
1727.7 | 608.0 |
Annotations: C |
|
1728.7 | 264.0 |
1729.6 | 230.0 |
Annotations: Y^{3,5}X_{Fuc} |
|
1735.6 | 218.0 |
1787.5 | 310.0 |
Annotations: Y |
|
1788.1 | 228.0 |
Annotations: Y |
|
1788.8 | 441.0 |
1789.7 | 156.0 |
1789.9 | 149.0 |
1857.7 | 102.0 |
Annotations: ^{0,2}X_{NeuAc} |
|
1900.6 | 111.0 |