Recombinant mucin-type fusion proteins with Galα1,3Gal substitution as Clostridium difficile toxin A inhibitors

PubMed Entry

GlyToucan Accession Number: G87514QJ

Peak Intensity
259.3 1.2
282.04 12.9

Annotations:

BY CZ
296.92 1.0
300.14 1.1

Annotations:

CY
315.16 3.1

Annotations:

^{3,5}A_{GlcNAc}
324.07 1.1

Annotations:

^{0,4}A_{GalNAc}Z B^{0,2}X_{Gal} ^{0,4}X_{Gal}Y ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y ^{0,4}X_{GalNAc} ^{1,3}X_{GalNAc}Y
341.35 1.7
342.15 3.5

Annotations:

^{0,4}A_{GalNAc}Y C^{0,2}X_{Gal}
343.23 0.9
347.4 1.9

Annotations:

Z^{2,4}X_{GlcNAc} ^{2,4}X_{GalNAc}Z
361.21 2.2

Annotations:

^{0,2}A_{GlcNAc}
372.35 1.7

Annotations:

C^{0,3}X_{Gal} C^{1,4}X_{Gal} ^{0,3}A_{GalNAc}Y
386.26 2.3

Annotations:

^{1,3}X_{GalNAc}Z
389.0 0.9

Annotations:

ZZ
396.68 1.6
425.31 1.4

Annotations:

YY
427.35 2.4

Annotations:

Z^{2,4}X_{GlcNAc} ^{2,4}X_{GalNAc}Z
427.94 0.8
428.26 1.0
444.21 83.3

Annotations:

B
445.15 11.7

Annotations:

Y^{2,4}X_{GlcNAc} ^{2,4}X_{GalNAc}Y
445.53 1.0

Annotations:

Y^{2,4}X_{GlcNAc} ^{2,4}X_{GalNAc}Y
464.35 1.2
485.26 1.2
486.08 1.2

Annotations:

^{1,3}X_{GlcNAc}Y Y^{1,3}X_{GlcNAc} ^{1,3}X_{GalNAc}
487.24 14.7

Annotations:

YZ ZY
504.26 6.7

Annotations:

^{0,4}A_{GalNAc}
505.26 222.6

Annotations:

YY
506.27 35.3
509.0 0.9

Annotations:

^{0,4}X_{GlcNAc}Z ^{0,4}X_{Gal}Z ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{0,4}X_{Gal} Z^{1,3}X_{Gal} Z^{2,4}X_{Gal} Z^{0,4}X_{GlcNAc}
512.67 1.0
529.99 1.2

Annotations:

^{2,5}A_{GalNAc}Z ^{2,5}A_{GalNAc}Z
531.2 1.2
533.94 1.7

Annotations:

^{0,3}A_{GalNAc}
534.32 6.8

Annotations:

^{0,3}A_{GalNAc}
535.08 1.3
547.3 1.0

Annotations:

^{0,2}X_{Gal}Y Y^{0,2}X_{Gal}
559.38 1.5

Annotations:

^{0,3}X_{Gal}Z ^{1,4}X_{Gal}Z Z^{0,3}X_{Gal} Z^{1,4}X_{Gal}
571.93 1.2
587.24 0.9

Annotations:

Y Y
589.23 5.8

Annotations:

^{0,4}X_{Gal}Z ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{0,4}X_{Gal} Z^{1,3}X_{Gal} Z^{2,4}X_{Gal}
590.33 1.7
590.59 1.0
594.12 1.3
607.22 10.2

Annotations:

^{0,4}X_{Gal}Y ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{2,4}X_{GalNAc} ^{2,4}X_{GlcNAc}
607.65 2.5

Annotations:

^{2,4}X_{GlcNAc} ^{0,4}X_{Gal}Y ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{2,4}X_{GalNAc}
608.42 1.3
610.37 1.9
616.22 1.9
619.36 1.9

Annotations:

^{1,5}A_{GalNAc}Y ^{1,5}A_{GalNAc}Y
625.44 2.2
626.33 1.6
627.0 2.7
631.34 0.9
632.37 1.2
633.34 2.0
634.14 1.5
639.61 0.8
648.17 2.1

Annotations:

^{1,3}X_{GlcNAc}
648.5 0.8

Annotations:

^{1,3}X_{GlcNAc}
649.18 31.6

Annotations:

Z Z
649.44 23.9

Annotations:

Z Z
650.28 2.3
651.82 0.9
665.04 2.2
666.31 3.3
667.33 1186.6

Annotations:

Y Y
668.32 238.9
669.08 2.2
670.28 1.2
671.09 0.8
705.65 2.0
708.41 1.4
709.21 1.6

Annotations:

^{0,2}X_{Gal} ^{0,2}X_{Gal}
709.66 1.0

Annotations:

^{0,2}X_{Gal} ^{0,2}X_{Gal}
710.2 3.5

Annotations:

^{2,5}A_{GalNAc}
710.41 1.4

Annotations:

^{2,5}A_{GalNAc}
725.07 1.3

Annotations:

^{2,5}X_{Gal} ^{2,5}X_{Gal}
731.2 2.7
739.31 3.9

Annotations:

^{0,3}X_{Gal} ^{1,4}X_{Gal} ^{0,3}X_{Gal} ^{1,4}X_{Gal}
740.36 0.8
748.21 0.8
756.48 1.7
765.14 1.0
767.21 1.1
769.32 9.1

Annotations:

^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal}
770.35 3.2
779.29 1.3
784.01 1.7
785.37 1.5
786.23 1.2
787.41 1.2
787.95 1.8
788.38 1.2
797.49 1.3
798.55 3.3
799.29 3.0
799.51 2.9
799.93 1.5
801.22 1.0

There are 9 similar spectra:

Id Structure Score

3058

1.00

2639

1.00

30

0.99

339

0.97

2820

0.94

340

0.87

77

0.81

104

0.80

2610

0.72
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