In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.
GlyToucan Accession Number: G37491LV
Peak | Intensity |
---|---|
368.1 | 219.0 |
Annotations: Y |
|
368.3 | 110.0 |
Annotations: Y |
|
389.1 | 116.0 |
Annotations: ZZ |
|
424.1 | 322.0 |
Annotations: ^{1,5}A_{Gal} ^{1,3}A_{Man} ^{1,3}A_{Man}Y ^{0,4}A_{Man}Y ^{1,3}A_{Man}Y ^{2,4}A_{Man}Y C^{0,2}X_{Gal} C^{0,2}X_{Gal} |
|
450.3 | 257.0 |
Annotations: B^{2,5}X_{NeuAc} |
|
470.1 | 136.0 |
Annotations: C |
|
528.0 | 249.0 |
553.2 | 174.0 |
Annotations: Z |
|
653.3 | 198.0 |
655.2 | 455.0 |
Annotations: B |
|
657.4 | 299.0 |
Annotations: ^{0,3}A_{Man}Y ^{1,4}A_{Man}Y ^{2,4}A_{GlcNAc}Y C^{0,2}X_{Gal} ^{1,5}A_{Man}Y |
|
670.2 | 806.0 |
Annotations: Z^{0,2}X_{Fuc} Z^{2,5}X_{GlcNAc} ^{2,5}X_{Gal}Z ^{2,5}X_{GlcNAc}Z Z^{2,5}X_{GlcNAc} Z^{2,5}X_{Gal} |
|
671.1 | 122.0 |
Annotations: ^{2,5}A_{GlcNAc}Z ^{2,5}A_{Man}Z Y^{0,2}X_{GlcNAc} Y^{0,2}X_{Gal} Y^{0,2}X_{GlcNAc} ^{0,2}X_{Gal}Y ^{0,2}X_{GlcNAc}Y |
|
693.8 | 270.0 |
Annotations: ^{1,4}X_{Man}Y ^{3,5}X_{Gal}Y ^{3,5}X_{GlcNAc}Y Y^{3,5}X_{GlcNAc} Y^{0,3}X_{Fuc} Y^{3,5}X_{Gal} Y^{3,5}X_{GlcNAc} |
|
702.8 | 500.0 |
715.3 | 182.0 |
Annotations: ^{1,3}A_{Man} C^{0,4}X_{NeuAc} C^{1,5}X_{Man} ^{1,5}A_{GlcNAc}Y ^{1,5}X_{GlcNAc}Z Z^{1,5}X_{GlcNAc} |
|
736.5 | 110.0 |
Annotations: ^{3,5}A_{GlcNAc}Z B^{3,5}X_{GlcNAc} Z^{1,5}X_{Gal} Z^{1,5}X_{Man} ^{1,5}X_{Gal}Z Z^{1,5}X_{GlcNAc} ^{1,5}X_{GlcNAc}Z |
|
767.5 | 238.0 |
Annotations: C^{2,5}X_{Gal} ^{1,5}X_{NeuAc}Y ^{0,3}X_{GlcNAc}Y Y^{1,4}X_{Fuc} Y^{0,3}X_{GlcNAc} ^{1,4}X_{Man} Y^{1,4}X_{Man} ^{0,3}X_{Gal}Y Y^{1,4}X_{GlcNAc} ^{1,4}X_{GlcNAc}Y Y^{0,3}X_{Gal} Y^{1,4}X_{Gal} C^{0,3}X_{NeuAc} |
|
774.9 | 212.0 |
Annotations: YY |
|
803.3 | 297.0 |
Annotations: Z |
|
803.7 | 332.0 |
Annotations: Z |
|
817.3 | 960.0 |
Annotations: B |
|
819.4 | 199.0 |
Annotations: CY |
|
820.2 | 103.0 |
835.3 | 1596.0 |
Annotations: C |
|
836.2 | 678.0 |
836.4 | 277.0 |
837.3 | 249.0 |
Annotations: B^{3,5}X_{GlcNAc} |
|
838.3 | 122.0 |
Annotations: ZZ |
|
854.4 | 524.0 |
Annotations: B |
|
854.8 | 661.0 |
Annotations: ^{2,5}X_{NeuAc}Y ^{0,4}X_{Gal}Z Z^{1,3}X_{GlcNAc} ^{1,3}X_{Man}Y Y^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Y ^{1,5}X_{Gal}Y Y^{1,5}X_{Fuc} C^{1,5}X_{NeuAc} |
|
856.2 | 109.0 |
Annotations: YY |
|
866.8 | 297.0 |
Annotations: ZZ |
|
872.4 | 127.0 |
875.4 | 215.0 |
Annotations: ZZ YZ ZY |
|
875.9 | 232.0 |
Annotations: YZ ZY |
|
876.3 | 342.0 |
Annotations: YZ ZY |
|
876.7 | 464.0 |
Annotations: Y |
|
880.2 | 125.0 |
884.3 | 948.0 |
Annotations: CY YZ ZY |
|
884.8 | 2160.0 |
Annotations: YZ ZY YY |
|
885.3 | 253.0 |
Annotations: YY |
|
885.9 | 1188.0 |
886.1 | 356.0 |
895.4 | 192.0 |
Annotations: ZZ |
|
932.7 | 185.0 |
Annotations: ^{0,3}X_{GlcNAc}Z |
|
935.5 | 120.0 |
Annotations: Z^{1,3}X_{GlcNAc} Y^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Y Y^{1,5}X_{Fuc} |
|
935.8 | 108.0 |
Annotations: Z^{1,3}X_{GlcNAc} Y^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Y Y^{1,5}X_{Fuc} |
|
937.4 | 305.0 |
Annotations: C^{1,5}X_{Man} |
|
943.3 | 228.0 |
Annotations: C^{1,3}X_{NeuAc} Y^{0,2}X_{Fuc} Y^{2,5}X_{Gal} Y^{2,5}X_{GlcNAc} ^{2,5}X_{Gal} ^{0,3}X_{NeuAc}Y |
|
947.9 | 406.0 |
Annotations: ZZ |
|
949.5 | 240.0 |
Annotations: ^{3,5}X_{GlcNAc}Y ^{1,5}X_{NeuAc}Y Y^{1,4}X_{Fuc} Y^{0,3}X_{Gal} Y^{1,4}X_{Gal} Y^{0,3}X_{GlcNAc} ^{0,3}X_{Gal} |
|
952.9 | 162.0 |
956.3 | 498.0 |
Annotations: B |
|
958.3 | 465.0 |
Annotations: Y |
|
962.3 | 112.0 |
968.2 | 116.0 |
Annotations: ZZ |
|
969.5 | 216.0 |
Annotations: ^{0,4}X_{NeuAc}Z Z^{0,2}X_{Gal} |
|
977.4 | 420.0 |
Annotations: YZ ZY |
|
977.8 | 867.0 |
Annotations: YZ ZY |
|
978.3 | 275.0 |
Annotations: Z^{0,2}X_{Fuc} Z^{2,5}X_{Gal} |
|
993.0 | 275.0 |
Annotations: ^{1,4}X_{NeuAc}Z ^{0,2}A_{Man}Z ^{0,2}A_{GlcNAc}Z B^{1,3}X_{Man} ^{1,4}X_{GlcNAc}Z Z^{0,3}X_{Fuc} Z^{3,5}X_{Gal} |
|
995.4 | 241.0 |
Annotations: ^{2,5}A_{GlcNAc}Y ^{2,5}A_{Man}Y |
|
996.1 | 176.0 |
1021.3 | 179.0 |
Annotations: Z^{3,5}X_{Fuc} ^{3,5}X_{Gal}Z ^{3,5}X_{GlcNAc}Z |
|
1026.3 | 200.0 |
1028.3 | 319.0 |
Annotations: ^{0,4}X_{Gal}Z ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z ^{0,4}X_{GlcNAc}Z ^{2,4}X_{GlcNAc}Z Z^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Z |
|
1028.9 | 202.0 |
Annotations: Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{2,4}X_{GlcNAc} ^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y |
|
1029.8 | 124.0 |
Annotations: Z |
|
1030.7 | 202.0 |
Annotations: ^{3,5}X_{Gal}Y Y^{3,5}X_{Fuc} ^{3,5}X_{GlcNAc}Y ^{1,5}X_{NeuAc} |
|
1037.3 | 217.0 |
Annotations: ^{0,4}X_{Gal}Y ^{2,4}X_{Gal}Y Y^{0,4}X_{Fuc} ^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y ^{1,3}X_{NeuAc}Y ^{1,3}X_{Gal}Y |
|
1037.8 | 215.0 |
Annotations: ^{0,4}X_{Gal}Y ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y Y^{0,4}X_{Fuc} ^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y ^{1,3}X_{NeuAc}Y ^{2,5}X_{NeuAc} |
|
1038.3 | 402.0 |
Annotations: ^{2,5}X_{NeuAc} ^{1,3}X_{Man}Y Y^{1,3}X_{Man} |
|
1038.9 | 264.0 |
Annotations: Y |
|
1039.8 | 209.0 |
1050.3 | 186.0 |
Annotations: Z |
|
1050.9 | 540.0 |
1052.0 | 310.0 |
1052.8 | 142.0 |
Annotations: ^{1,5}X_{GlcNAc} ^{3,5}X_{NeuAc} |
|
1058.5 | 1516.0 |
Annotations: Z |
|
1059.0 | 1763.0 |
Annotations: Y |
|
1059.4 | 1048.0 |
Annotations: Y |
|
1059.9 | 1686.0 |
1060.4 | 962.0 |
1060.8 | 137.0 |
1067.5 | 127.0 |
Annotations: Y |
|
1067.9 | 532.0 |
1081.4 | 278.0 |
Annotations: B^{1,5}X_{GlcNAc} ^{1,5}X_{Fuc} |
|
1082.2 | 142.0 |
1089.9 | 298.0 |
Annotations: ^{1,3}X_{GlcNAc} ^{2,4}X_{NeuAc} |
|
1090.4 | 282.0 |
1105.9 | 188.0 |
1109.9 | 236.0 |
Annotations: ^{1,4}A_{Man} |
|
1110.5 | 621.0 |
Annotations: ^{1,4}A_{Man} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{GlcNAc} ^{2,4}X_{GlcNAc} ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} |
|
1111.0 | 383.0 |
Annotations: ^{3,5}X_{Fuc} |
|
1111.5 | 780.0 |
Annotations: ^{3,5}X_{Fuc} |
|
1114.1 | 169.0 |
1119.4 | 1398.0 |
1120.0 | 1335.0 |
1120.4 | 559.0 |
1120.9 | 217.0 |
1131.5 | 101.0 |
1132.6 | 199.0 |
1155.5 | 110.0 |
Annotations: ^{0,2}A_{GlcNAc}Z |
|
1224.3 | 369.0 |
Annotations: ZZ ZZ |
|
1268.2 | 224.0 |
Annotations: ^{2,5}A_{GlcNAc}Z ^{2,5}A_{Man}Z |
|
1286.6 | 180.0 |
Annotations: ^{2,5}A_{GlcNAc}Y ^{2,5}A_{Man}Y |
|
1369.4 | 158.0 |
Annotations: ^{1,4}A_{GlcNAc}Z B^{0,3}X_{GlcNAc} |
|
1408.3 | 215.0 |
1421.8 | 137.0 |
1441.5 | 261.0 |
Annotations: BZ |
|
1460.6 | 114.0 |
Annotations: ^{2,4}A_{GlcNAc}Z |
|
1463.6 | 171.0 |
Annotations: Y |
|
1465.5 | 123.0 |
1466.7 | 208.0 |
1507.7 | 121.0 |
Annotations: ^{1,5}X_{GlcNAc}Y Y^{1,5}X_{Fuc} |
|
1524.8 | 113.0 |
Annotations: CY |
|
1546.5 | 108.0 |
Annotations: Y^{0,2}X_{GlcNAc} ^{0,2}X_{GlcNAc}Y |
|
1548.6 | 117.0 |
Annotations: ^{2,4}A_{GlcNAc}Z |
|
1549.7 | 523.0 |
Annotations: ^{1,4}A_{GlcNAc}Y C^{0,3}X_{Gal} ^{2,5}X_{NeuAc}Y Z^{3,5}X_{Fuc} |
|
1552.7 | 141.0 |
Annotations: C^{1,5}X_{GlcNAc} C^{3,5}X_{NeuAc} |
|
1565.5 | 243.0 |
Annotations: CY CY |
|
1567.4 | 134.0 |
Annotations: Y^{3,5}X_{Fuc} |
|
1567.7 | 146.0 |
Annotations: Y^{3,5}X_{Fuc} |
|
1572.5 | 118.0 |
Annotations: ZZ |
|
1592.4 | 173.0 |
Annotations: ^{2,5}A_{GlcNAc}Z Y^{3,5}X_{GlcNAc} ^{0,3}X_{GlcNAc}Y ^{3,5}X_{GlcNAc}Y |
|
1621.6 | 220.0 |
Annotations: BY CZ |
|
1649.6 | 357.0 |
Annotations: ^{0,2}A_{GlcNAc}Z B^{0,4}X_{Gal} B^{1,3}X_{Gal} B^{2,4}X_{Gal} B^{0,4}X_{GlcNAc} B^{2,4}X_{GlcNAc} ^{0,2}X_{Gal}Z |
|
1677.8 | 168.0 |
Annotations: ZZ |
|
1709.6 | 161.0 |
Annotations: B |
|
1710.7 | 230.0 |
Annotations: ^{1,3}X_{Man}Y Y^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Y ^{1,5}X_{Gal}Y Y^{1,5}X_{Fuc} |
|
1716.6 | 172.0 |
1727.5 | 507.0 |
Annotations: C |
|
1727.8 | 501.0 |
Annotations: C |
|
1728.6 | 616.0 |
1729.8 | 364.0 |
1730.7 | 117.0 |
1733.7 | 184.0 |
1737.7 | 132.0 |
Annotations: B^{1,5}X_{GlcNAc} B^{3,5}X_{NeuAc} |
|
1752.6 | 433.0 |
Annotations: ZY YZ |
|
1754.8 | 101.0 |
Annotations: Y |
|
1769.3 | 118.0 |
Annotations: YZ ZY |
|
1769.8 | 232.0 |
Annotations: YZ ZY |
|
1771.0 | 458.0 |
Annotations: YY |
|
1815.9 | 181.0 |
Annotations: C^{1,4}X_{NeuAc} Y^{1,5}X_{GlcNAc} ^{1,3}X_{GlcNAc}Y ^{2,4}X_{NeuAc}Y |
|
1828.6 | 195.0 |
Annotations: Y |
|
1828.8 | 616.0 |
Annotations: Y |
|
1829.8 | 369.0 |
Annotations: C^{1,3}X_{GlcNAc} C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc} |
|
1830.8 | 115.0 |
1831.8 | 193.0 |
1837.7 | 141.0 |
1845.7 | 138.0 |
1856.8 | 137.0 |
Annotations: C^{3,5}X_{Gal} C^{3,5}X_{GlcNAc} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{1,5}X_{Gal} ^{1,3}X_{Man} ^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y Y^{2,4}X_{GlcNAc} ^{1,5}X_{Gal} |
|
1890.8 | 443.0 |
1894.7 | 261.0 |
1895.0 | 143.0 |
1912.7 | 507.0 |
Annotations: B |
|
1913.8 | 387.0 |
Annotations: ^{2,4}X_{GlcNAc}Y |
|
1914.4 | 277.0 |
Annotations: YZ ZY |
|
1914.7 | 122.0 |
Annotations: YZ ZY |
|
1915.8 | 147.0 |
1917.9 | 217.0 |
1926.5 | 200.0 |
Annotations: ^{0,3}X_{NeuAc}Z ^{1,5}X_{GlcNAc}Z Z^{1,5}X_{Gal} ^{3,5}X_{NeuAc}Z |
|
1931.9 | 693.0 |
1948.8 | 100.0 |
1990.8 | 461.0 |
Annotations: Y |
|
1991.9 | 131.0 |
1992.7 | 292.0 |
1993.9 | 120.0 |