In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.

PubMed Entry

GlyToucan Accession Number: G74784VI

Peak Intensity
290.0 228.0

Annotations:

B
305.0 514.0

Annotations:

BZ BZ
305.2 221.0

Annotations:

BZ BZ
368.0 105.0

Annotations:

^{0,3}A_{GlcNAc}Y C^{1,4}X_{Man}
470.3 166.0

Annotations:

C
485.2 113.0

Annotations:

B
487.2 213.0

Annotations:

^{0,2}X_{Gal}Z Z^{0,2}X_{Man}
503.0 409.0

Annotations:

C
503.2 186.0

Annotations:

C
509.3 105.0
608.7 116.0

Annotations:

Z
611.1 250.0

Annotations:

B^{1,3}X_{NeuAc} Z^{0,2}X_{Man}
611.3 133.0

Annotations:

B^{1,3}X_{NeuAc} Z^{0,2}X_{Man} B^{0,2}X_{Man}
613.3 115.0

Annotations:

^{2,5}A_{Man}Z ^{2,5}A_{Man}Z C^{1,5}X_{Man}
629.2 323.0

Annotations:

YZ YZ ZY ZY BZ
650.1 141.0

Annotations:

Z^{0,2}X_{Man} Z^{0,2}X_{Man} ^{0,2}X_{Gal}Z ^{0,2}X_{Gal}Z
656.2 420.0
673.1 141.0

Annotations:

C
681.4 460.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y C^{0,2}X_{Man} C^{0,2}X_{Man} C^{0,4}X_{NeuAc} B^{2,4}X_{NeuAc} ^{3,5}X_{Gal}Y ^{3,5}X_{Gal}Y Y^{3,5}X_{Man} Y^{3,5}X_{Man} ^{3,5}X_{GlcNAc}
681.8 120.0

Annotations:

Y^{3,5}X_{Man} B^{2,4}X_{NeuAc} ^{3,5}X_{Gal}Y ^{3,5}X_{Gal}Y Y^{3,5}X_{Man} ^{3,5}X_{GlcNAc}
682.1 155.0

Annotations:

B^{2,4}X_{NeuAc} ^{3,5}X_{Gal}Y ^{3,5}X_{Gal}Y Y^{3,5}X_{Man} Y^{3,5}X_{Man} ^{3,5}X_{GlcNAc}
682.8 119.0
753.2 303.0

Annotations:

BY BY CZ CZ
753.8 264.0

Annotations:

^{0,2}X_{NeuAc}Y ^{0,2}X_{NeuAc}Y Z^{3,5}X_{Man} Z^{3,5}X_{Man}
762.3 1424.0

Annotations:

^{2,4}A_{GlcNAc} Y^{3,5}X_{Man} Y^{3,5}X_{Man} ^{3,5}X_{Gal}
762.8 441.0

Annotations:

Y^{3,5}X_{Man} Y^{3,5}X_{Man} ^{3,5}X_{Gal} ^{1,5}A_{Man}Z
763.3 561.0

Annotations:

^{1,5}A_{Man}Z
764.1 340.0
789.3 249.0

Annotations:

Z^{2,5}X_{Man} ^{1,5}A_{Man}
792.3 123.0

Annotations:

C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc}
797.3 131.0

Annotations:

C^{1,4}X_{Man} C^{0,3}X_{Man} C^{1,4}X_{Man} ^{1,4}X_{NeuAc}Z ^{1,4}X_{NeuAc}Z ^{1,5}X_{Man}Y Y^{1,5}X_{Man} ^{1,4}A_{GlcNAc} C^{0,3}X_{Man}
804.8 160.0

Annotations:

^{2,4}X_{NeuAc}Z ^{2,4}X_{NeuAc}Z
812.3 359.0

Annotations:

^{2,5}X_{Man}Y Y^{2,5}X_{Man} C^{0,4}X_{Man} C^{1,3}X_{Man} C^{2,4}X_{Man} C^{0,4}X_{Man} C^{1,3}X_{Man} C^{2,4}X_{Man}
813.2 260.0

Annotations:

C^{0,4}X_{Man} C^{1,3}X_{Man} C^{2,4}X_{Man} C^{0,4}X_{Man} C^{1,3}X_{Man} C^{2,4}X_{Man}
813.7 449.0

Annotations:

^{2,4}X_{NeuAc}Y ^{2,4}X_{NeuAc}Y
814.3 152.0

Annotations:

^{0,2}X_{GlcNAc}Z
817.0 264.0

Annotations:

B
817.3 990.0

Annotations:

B
818.2 191.0

Annotations:

^{3,5}X_{Man}Z Z^{3,5}X_{Man}
818.5 421.0

Annotations:

^{3,5}X_{Man}Z Z^{3,5}X_{Man}
833.8 351.0

Annotations:

B
834.3 689.0

Annotations:

^{2,4}X_{Man}Y Y^{0,4}X_{Man} Y^{1,3}X_{Man} Y^{2,4}X_{Man} ^{0,2}X_{NeuAc} ^{0,4}X_{Man}Y ^{1,3}X_{Man}Y
834.7 438.0

Annotations:

^{0,4}X_{Man}Y ^{1,3}X_{Man}Y ^{2,4}X_{Man}Y Y^{0,4}X_{Man} Y^{1,3}X_{Man} Y^{2,4}X_{Man} ^{0,2}X_{NeuAc}
834.8 431.0

Annotations:

C
835.4 1699.0

Annotations:

C
836.3 1408.0
837.2 220.0

Annotations:

B^{1,5}X_{GlcNAc}
837.4 192.0

Annotations:

B^{1,5}X_{GlcNAc}
843.2 114.0

Annotations:

C
864.3 413.0

Annotations:

Y Y
864.8 443.0

Annotations:

Y Y
865.2 110.0

Annotations:

^{3,5}A_{GlcNAc}Z
865.4 105.0

Annotations:

^{3,5}A_{GlcNAc}Z
877.2 212.0

Annotations:

^{1,3}A_{Man} ^{2,4}A_{Man}
885.4 231.0

Annotations:

^{0,2}X_{Man} ^{0,2}X_{Man} ^{0,4}X_{NeuAc}
894.3 206.0
894.8 738.0

Annotations:

^{2,4}X_{NeuAc} ^{2,5}A_{GlcNAc}Z
895.4 335.0

Annotations:

^{2,5}A_{GlcNAc}Z
903.2 165.0
906.4 188.0
908.4 145.0

Annotations:

B^{2,5}X_{GlcNAc} ^{3,5}X_{Man} ^{3,5}X_{Man}
914.5 145.0
915.0 396.0

Annotations:

^{1,3}X_{Man} ^{2,4}X_{Man} ^{0,4}X_{Man} ^{1,3}X_{Man} ^{2,4}X_{Man} ^{0,4}X_{Man}
915.4 1706.0

Annotations:

^{0,4}X_{Man} ^{1,3}X_{Man} ^{2,4}X_{Man} ^{0,4}X_{Man} ^{1,3}X_{Man} ^{2,4}X_{Man}
915.8 1600.0

Annotations:

^{0,4}X_{Man} ^{1,3}X_{Man} ^{2,4}X_{Man} ^{0,4}X_{Man} ^{1,3}X_{Man} ^{2,4}X_{Man}
916.3 154.0

Annotations:

ZZ
924.3 485.0
924.9 325.0
925.6 187.0
926.3 256.0

Annotations:

C^{2,5}X_{GlcNAc}
935.8 217.0

Annotations:

Z^{0,2}X_{Man} Z^{0,2}X_{Man}
936.2 195.0

Annotations:

^{2,5}A_{Man}Z
1054.5 107.0

Annotations:

^{2,4}A_{GlcNAc}Z B^{0,2}X_{Gal} ^{0,4}X_{Gal}Y
1073.4 134.0

Annotations:

Y
1322.3 144.0
1365.6 266.0
1369.5 145.0
1382.6 183.0

Annotations:

C^{2,4}X_{NeuAc}
1388.3 161.0
1392.5 269.0
1420.8 299.0

Annotations:

Z
1438.6 311.0

Annotations:

Y
1469.7 106.0
1483.6 701.0

Annotations:

C
1484.5 340.0
1485.6 287.0
1506.6 127.0

Annotations:

BY BY CZ CZ
1508.6 103.0

Annotations:

^{0,2}X_{NeuAc}Y ^{0,2}X_{NeuAc}Y Z^{3,5}X_{Man} Z^{3,5}X_{Man}
1509.5 267.0
1524.5 118.0

Annotations:

CY CY
1531.7 133.0

Annotations:

ZZ
1539.6 137.0

Annotations:

^{3,5}A_{GlcNAc}
1568.8 181.0
1585.4 115.0

Annotations:

C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc}
1586.6 158.0
1600.8 230.0

Annotations:

Y
1603.0 247.0
1669.6 466.0

Annotations:

^{0,4}X_{Man}Y ^{1,3}X_{Man}Y ^{2,4}X_{Man}Y Y^{0,4}X_{Man} Y^{1,3}X_{Man} Y^{2,4}X_{Man}
1670.5 173.0

Annotations:

^{0,2}X_{NeuAc}
1670.7 563.0

Annotations:

^{0,2}X_{NeuAc}
1686.9 226.0

Annotations:

C
1687.6 127.0

There are 4 similar spectra:

Id Structure Score

2206

0.77

2332

0.65

2331

0.64

430

0.56
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