Cystic fibrosis and bacterial colonization define the sputum N-glycosylation phenotype

PubMed Entry

GlyToucan Accession Number: G73717EV

Peak Intensity
290.1 1088.0

Annotations:

B
291.0 501.0

Annotations:

B^{1,5}X_{NeuAc} ^{1,4}A_{Man}Z ^{1,4}A_{Man}Z B^{0,3}X_{Gal}
302.1 113.0

Annotations:

^{0,2}A_{GlcNAc}Y
308.1 418.0

Annotations:

C
309.1 216.0
350.1 407.0

Annotations:

Z
367.8 103.0

Annotations:

Y
370.2 415.0

Annotations:

B^{1,3}X_{Fuc} B^{2,4}X_{Fuc} B^{0,2}X_{NeuAc}
383.3 173.0

Annotations:

^{2,4}A_{GlcNAc}Y
407.3 113.0

Annotations:

ZY YZ BZ
408.3 195.0

Annotations:

BY CZ
435.2 134.0

Annotations:

^{1,5}X_{Man}Z Z^{1,5}X_{Fuc}
452.1 342.0

Annotations:

B
470.1 4185.0

Annotations:

C
471.2 915.0
472.2 304.0
485.0 132.0

Annotations:

BY CZ
545.2 460.0

Annotations:

^{2,4}A_{GlcNAc}Y
553.2 280.0

Annotations:

Z
571.0 120.0

Annotations:

Y
571.2 242.0

Annotations:

Y
572.1 137.0

Annotations:

C^{1,5}X_{Man}
572.4 170.0

Annotations:

C^{1,5}X_{Man}
577.3 195.0
582.4 109.0

Annotations:

B^{1,5}X_{NeuAc} ^{1,4}A_{Man}Z ^{1,4}A_{Man}Z B^{0,3}X_{Gal}
622.1 123.0

Annotations:

YY
637.1 517.0

Annotations:

BZ
640.1 170.0
647.2 137.0
664.3 464.0

Annotations:

^{3,5}X_{Gal}Z Z^{3,5}X_{Gal} Z^{3,5}X_{Fuc} ^{3,5}X_{Fuc}Z
670.0 237.0

Annotations:

BZ
672.3 106.0

Annotations:

CZ BY CY
673.2 322.0

Annotations:

CY CY
673.6 190.0

Annotations:

CY
674.0 132.0

Annotations:

^{3,5}X_{Gal}Y Y^{3,5}X_{Gal} Y^{3,5}X_{Fuc} ^{3,5}X_{Fuc}Y
685.2 317.0

Annotations:

ZZ
688.4 125.0

Annotations:

BY CZ
712.5 113.0
724.9 140.0

Annotations:

C^{3,5}X_{Fuc} Y^{1,5}X_{Fuc} ^{1,5}X_{Fuc}Y
725.3 107.0
732.4 302.0

Annotations:

^{1,3}A_{Man}Y ^{2,4}A_{Man}Y
742.3 356.0

Annotations:

B^{0,2}X_{NeuAc}
744.7 328.0

Annotations:

B
745.3 521.0

Annotations:

C^{0,3}X_{Fuc} ^{1,4}A_{Man}Y ^{0,2}X_{NeuAc}Y Y^{0,2}X_{NeuAc} ^{2,5}X_{NeuAc}Y Z^{3,5}X_{Fuc} ^{3,5}X_{Fuc}Z
755.6 200.0
763.3 202.0
767.4 155.0
769.3 138.0
771.0 188.0

Annotations:

^{1,5}A_{Man}Z
781.8 538.0

Annotations:

^{1,4}X_{NeuAc}Z
783.3 102.0

Annotations:

Y
783.8 186.0

Annotations:

Y
784.2 106.0

Annotations:

Y
789.0 136.0

Annotations:

^{2,4}X_{NeuAc}Z ^{1,5}A_{Man}Y ^{1,5}X_{Fuc}Y ^{1,5}X_{Man}Y Y^{1,5}X_{Fuc} Y^{1,5}X_{Man} Z^{2,5}X_{Fuc}
798.4 141.0

Annotations:

^{1,4}X_{NeuAc}Y Y^{1,4}X_{NeuAc}
800.2 123.0
801.4 1708.0

Annotations:

B
802.2 556.0

Annotations:

^{0,3}X_{Fuc}Z ^{1,4}X_{Fuc}Z Z^{1,4}X_{Fuc} ^{0,3}X_{Man}Z ^{1,4}X_{Man}Z Z^{0,3}X_{Fuc} Z^{0,3}X_{Man} Z^{1,4}X_{Man}
817.4 458.0

Annotations:

BY CZ
817.7 753.0

Annotations:

BY CZ
818.8 131.0

Annotations:

C
825.5 226.0

Annotations:

^{0,4}X_{Fuc}Z ^{1,3}X_{NeuAc}Z Z^{0,4}X_{Fuc} Z^{1,3}X_{NeuAc}
826.3 554.0

Annotations:

^{0,4}X_{Man}Y ^{1,3}X_{Man}Y ^{2,4}X_{Man}Y Y^{0,4}X_{Fuc} Y^{0,4}X_{Man} Y^{1,3}X_{Man} Y^{2,4}X_{Man} ^{2,5}X_{NeuAc} ^{0,4}X_{Fuc}Y ^{1,3}X_{Fuc}Y ^{2,4}X_{Fuc}Y Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{1,3}X_{NeuAc}Y
826.9 975.0

Annotations:

^{2,5}X_{NeuAc} ^{3,5}X_{Fuc}Y Y^{3,5}X_{Fuc}
827.4 292.0

Annotations:

^{3,5}X_{Fuc}Y Y^{3,5}X_{Fuc}
827.8 244.0
833.5 167.0

Annotations:

^{1,3}X_{Man}Z Z^{0,4}X_{Fuc} ^{0,3}X_{NeuAc}
838.3 181.0
839.0 202.0

Annotations:

Z
839.9 204.0
843.2 143.0

Annotations:

B^{0,4}X_{NeuAc}
843.5 111.0

Annotations:

B^{0,4}X_{NeuAc}
844.2 247.0
847.3 1431.0

Annotations:

Z Z
847.9 2188.0

Annotations:

Y
848.3 1375.0

Annotations:

Y
849.0 383.0
849.9 116.0
851.4 337.0

Annotations:

^{1,3}X_{Man}Y Y^{0,4}X_{Fuc}
852.4 233.0

Annotations:

CY
857.4 251.0
869.4 796.0

Annotations:

^{0,2}X_{Man} ^{0,4}X_{NeuAc}
876.6 147.0

Annotations:

^{2,4}A_{GlcNAc}Z B^{0,2}X_{Gal}
877.3 411.0

Annotations:

Z
880.6 103.0

Annotations:

C^{1,5}X_{Gal} C^{2,4}X_{NeuAc}
881.9 200.0
890.9 205.0

Annotations:

^{1,4}A_{Man} C^{1,4}X_{Fuc}
893.4 1457.0

Annotations:

YZ ZY
894.4 723.0

Annotations:

^{2,4}A_{GlcNAc}Y C^{0,2}X_{Gal}
895.4 946.0

Annotations:

Y
896.3 236.0
897.7 706.0
898.0 191.0
899.4 731.0

Annotations:

^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Man} ^{1,3}X_{Man} ^{2,4}X_{Man}
899.8 768.0

Annotations:

^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Man} ^{1,3}X_{Man} ^{2,4}X_{Man}
900.4 236.0

Annotations:

^{3,5}X_{Fuc} ^{3,5}X_{Fuc}
908.3 241.0

Annotations:

^{3,5}A_{GlcNAc}Y
908.9 227.0
909.5 211.0
909.9 260.0

Annotations:

C^{2,5}X_{Gal}
910.8 221.0

Annotations:

C^{2,5}X_{Gal}
911.5 199.0

Annotations:

YY
912.3 327.0
913.3 349.0
920.1 113.0

Annotations:

^{2,5}A_{GlcNAc}Z ^{2,5}A_{Man}Z
920.3 774.0

Annotations:

^{2,5}A_{GlcNAc}Z ^{2,5}A_{Man}Z
921.0 174.0

Annotations:

C^{1,3}X_{Fuc} C^{2,4}X_{Fuc} Z^{1,5}X_{Fuc}
921.2 232.0

Annotations:

C^{1,3}X_{Fuc} C^{2,4}X_{Fuc} Z^{1,5}X_{Fuc}
921.3 214.0

Annotations:

Z^{1,5}X_{Fuc} C^{1,3}X_{Fuc} C^{2,4}X_{Fuc}
939.5 101.0

Annotations:

Y^{1,5}X_{Fuc}
955.8 276.0
963.2 253.0

Annotations:

B
964.1 298.0
970.5 396.0
976.5 155.0
981.4 3114.0

Annotations:

C
982.3 1099.0
983.3 435.0

Annotations:

Y^{0,3}X_{Fuc} Y^{3,5}X_{Man}
984.5 142.0
988.2 139.0
997.5 301.0

Annotations:

Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{0,4}X_{Man} Y^{1,3}X_{Man} Y^{2,4}X_{Man} ^{1,3}X_{Man}
998.3 125.0
999.6 126.0

Annotations:

Y^{3,5}X_{Fuc}
1001.3 370.0
1015.4 434.0
1015.7 486.0
1016.4 107.0
1017.7 132.0
1018.5 110.0
1019.3 302.0

Annotations:

BZ
1023.4 149.0

Annotations:

^{1,3}A_{Man} ^{2,4}A_{Man}
1024.4 133.0
1030.2 174.0
1030.5 505.0
1031.4 631.0
1037.3 120.0

Annotations:

BY CZ
1039.3 192.0

Annotations:

Z
1039.5 154.0

Annotations:

Z
1040.5 272.0
1041.4 351.0
1053.4 134.0

Annotations:

^{1,4}A_{Man}
1056.5 170.0

Annotations:

^{2,4}A_{GlcNAc}Y
1057.5 5464.0

Annotations:

Y
1058.5 3099.0
1059.4 501.0
1060.2 242.0
1060.5 557.0
1061.4 360.0
1065.5 148.0

Annotations:

B^{1,5}X_{Gal} ^{2,5}A_{Man}Z
1099.4 126.0

Annotations:

^{0,2}A_{Man}Y
1134.6 671.0
1136.3 148.0
1141.4 163.0

Annotations:

BY CZ
1143.2 103.0

Annotations:

CY
1143.5 161.0

Annotations:

CY
1146.5 148.0
1152.7 409.0
1153.4 491.0

Annotations:

B^{1,5}X_{Man} ^{1,5}A_{GlcNAc}Z
1154.6 289.0
1165.6 105.0
1166.5 138.0
1167.4 363.0

Annotations:

^{2,4}A_{GlcNAc}Z B^{0,2}X_{Man} B^{0,4}X_{NeuAc}
1181.4 239.0

Annotations:

BZ
1182.5 557.0
1182.7 474.0
1183.5 445.0

Annotations:

^{2,4}A_{GlcNAc}Z B^{0,2}X_{Fuc} B^{2,5}X_{Man}
1184.5 606.0
1194.5 1371.0
1195.4 566.0
1197.4 230.0

Annotations:

^{0,3}A_{GlcNAc}Z ^{3,5}A_{GlcNAc}Z B^{1,4}X_{Fuc} B^{0,3}X_{Man} B^{1,4}X_{Man}
1206.6 147.0
1216.5 151.0
1224.1 135.0

Annotations:

ZZ ZZ
1224.5 781.0

Annotations:

ZZ ZZ
1225.4 369.0
1225.6 295.0
1226.7 111.0

Annotations:

ZY YZ
1242.4 320.0

Annotations:

YZ ZY ZY YZ
1243.5 119.0

Annotations:

B^{0,4}X_{Fuc} B^{1,3}X_{NeuAc} ^{0,2}A_{GlcNAc}Z
1243.7 109.0

Annotations:

B^{0,4}X_{Fuc} B^{1,3}X_{NeuAc} ^{0,2}A_{GlcNAc}Z
1244.5 143.0

Annotations:

YY
1270.4 135.0

Annotations:

^{1,5}X_{Gal}Z Z^{1,5}X_{Gal} Z^{1,5}X_{Fuc} ^{1,5}X_{Fuc}Z
1273.7 121.0
1287.6 989.0

Annotations:

B
1288.5 356.0

Annotations:

^{1,5}X_{Gal}Y Y^{1,5}X_{Gal} Y^{1,5}X_{Fuc} ^{1,5}X_{Fuc}Y
1305.5 2852.0

Annotations:

C
1306.5 1212.0
1307.5 569.0
1309.5 127.0
1330.3 122.0

Annotations:

^{3,5}X_{Fuc}Z ^{3,5}X_{Gal}Z Z^{3,5}X_{Gal} Z^{3,5}X_{Fuc}
1347.4 137.0

Annotations:

^{2,4}A_{GlcNAc}
1362.7 181.0

Annotations:

CY
1364.2 201.0
1364.5 148.0
1365.8 129.0
1366.6 232.0
1389.5 462.0

Annotations:

B^{2,4}X_{NeuAc}
1390.5 445.0

Annotations:

C^{1,5}X_{Fuc}
1391.7 112.0

Annotations:

^{2,5}A_{GlcNAc}
1401.5 101.0
1404.5 432.0

Annotations:

YZ ZY ZY YZ
1404.7 326.0

Annotations:

YZ ZY ZY YZ
1405.4 360.0
1405.6 605.0
1406.5 1006.0

Annotations:

Y
1407.5 1934.0

Annotations:

C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc}
1408.2 315.0
1408.6 894.0
1409.5 404.0
1409.7 175.0
1410.5 239.0
1466.5 173.0
1467.5 123.0
1472.6 118.0
1490.6 1394.0

Annotations:

B
1491.2 431.0
1491.6 646.0
1492.6 172.0

Annotations:

^{0,2}X_{NeuAc}Y Y^{0,2}X_{NeuAc} ^{2,5}X_{NeuAc}Y Z^{3,5}X_{Fuc} ^{3,5}X_{Fuc}Z
1492.8 147.0

Annotations:

^{0,2}X_{NeuAc}Y Y^{0,2}X_{NeuAc} ^{2,5}X_{NeuAc}Y Z^{3,5}X_{Fuc} ^{3,5}X_{Fuc}Z
1508.0 228.0
1508.5 1038.0

Annotations:

C
1508.7 867.0

Annotations:

C
1509.6 1320.0
1510.7 727.0

Annotations:

Y^{3,5}X_{Fuc} ^{3,5}X_{Fuc}Y
1511.5 250.0
1526.6 274.0
1527.8 157.0
1550.3 222.0

Annotations:

Z
1550.7 160.0

Annotations:

Z
1568.6 3413.0

Annotations:

Y
1569.7 2528.0
1570.7 1449.0
1571.6 249.0
1572.1 151.0
1572.6 195.0
1608.6 138.0
1638.5 250.0

Annotations:

^{0,2}X_{NeuAc}
1696.7 155.0

There are 2 similar spectra:

Id Structure Score

2203

0.77

2202

0.59
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