Detailed O-glycomics of the Muc2 mucin from colon of wild-type, core 1- and core 3-transferase-deficient mice highlights differences compared with human MUC2

PubMed Entry

Peak Intensity
205.02 0.3
210.06 0.6
217.0 0.4

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B^{1,4}X_{Fuc}
225.91 0.4
244.07 0.4
247.05 0.4

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B^{1,3}X_{Fuc} B^{2,4}X_{Fuc}
268.98 1.0
272.29 0.6
290.06 39.8

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B
290.92 0.6
291.28 2.3
292.3 1.1
301.86 0.6
327.97 0.4
329.05 0.5
340.07 0.4
372.23 0.5
383.13 0.3
387.96 0.3
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399.66 1.0
406.98 0.4

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YZ ZY
411.02 0.5
433.07 0.5
454.28 1.0

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C^{1,5}X_{NeuAc} ^{3,5}X_{Fuc}Z
462.11 0.4
465.0 0.3
468.08 0.6

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C^{2,5}X_{NeuAc} ^{0,4}X_{Fuc}Z
468.52 0.6

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C^{2,5}X_{NeuAc} ^{0,4}X_{Fuc}Z
477.36 0.6
490.78 0.3
496.96 0.4
512.0 0.4

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Z
515.48 0.8
520.86 0.7
529.9 0.8

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Y
533.88 0.6
545.77 0.7
547.12 0.5
548.87 0.4

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BZ
550.19 0.5
558.05 1.1

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C^{1,4}X_{NeuAc}
562.3 0.5
563.17 0.5
566.77 1.3

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BY CZ
567.2 0.8

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BY CZ
567.43 0.7

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BY CZ
570.06 0.9
573.19 0.4
575.97 0.5
580.3 5.9
580.95 0.6

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B^{3,5}X_{HexNAc}
587.04 0.5

Annotations:

YY
588.58 4.2
589.18 0.9
589.97 0.9
593.3 0.6
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602.53 0.5
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606.33 0.6
619.89 0.4
620.46 0.5
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623.71 9.5
624.1 2.6
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^{1,4}X_{Fuc}Z
627.11 0.5

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^{2,5}X_{Fuc}Z
628.08 0.9
629.68 0.5

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C^{1,3}X_{NeuAc} ^{0,2}X_{Fuc}Y
630.05 0.6
631.95 0.9
632.5 3.1
632.77 1.6
634.24 1.4
635.24 2.1
635.57 0.7
635.98 0.4
639.64 0.7

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B^{1,5}X_{NeuAc}
641.49 0.4

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^{0,3}X_{Fuc}Z
643.08 0.4

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^{1,4}X_{Fuc}Y
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646.45 0.6
647.14 0.6

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BY CZ
648.0 0.5
648.61 0.6
648.91 0.4

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YZ ZY
649.35 0.6

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YZ ZY
650.3 1.3
651.28 1.2
653.05 0.5

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B^{2,5}X_{NeuAc}
659.73 0.5

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^{0,3}X_{Fuc}Y
660.19 0.7
661.27 7.2
661.76 4.2
662.52 0.5
668.39 1.0
670.96 1.0

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C^{2,5}X_{NeuAc} ^{0,4}X_{Fuc}Z
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672.04 0.7
675.32 0.5

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^{3,5}X_{Fuc}Y
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677.27 1.0

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^{1,5}X_{Fuc}Z
680.1 2.3
681.79 1.0
685.73 0.5

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C^{0,3}X_{NeuAc}
686.15 1.3
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687.09 0.4
688.06 1.1
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688.88 1.4

Annotations:

^{0,4}X_{Fuc}Y
689.19 3.6

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^{0,4}X_{Fuc}Y
689.98 2.8
690.18 2.3
690.41 0.5
691.26 1.0

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^{0,2}X_{Fuc}Z
692.23 1.3
693.15 0.9
694.36 1.0
695.12 4.6

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^{1,5}X_{Fuc}Y
695.55 3.8

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^{1,5}X_{Fuc}Y
696.02 2.6
697.2 1.3
697.72 0.5
698.24 1.0
699.08 0.7
702.59 1.5
702.96 1.1
703.19 1.0
703.44 0.9
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^{1,4}X_{Fuc}Z
705.86 0.7
707.46 0.4

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^{2,5}X_{Fuc}Z
710.21 0.7
795.66 0.6

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Z
812.88 0.4

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Y
813.85 0.8

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B^{1,3}X_{NeuAc}
814.44 1.4

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B^{1,3}X_{NeuAc}
815.21 0.5
816.36 0.9

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C^{0,4}X_{HexNAc} C^{2,4}X_{HexNAc}
829.17 1.4
834.2 0.6

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ZZ
841.26 0.5

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C^{1,4}X_{NeuAc}
846.15 0.9
852.25 11.5

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YZ ZY
853.16 4.1
853.42 1.8
853.81 0.6
855.13 1.0

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C^{1,3}X_{HexNAc} C^{2,4}X_{NeuAc}
860.35 0.7

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YZ ZY
869.91 3.3

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YY
870.31 0.4

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YY
877.15 0.4

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YZ ZY
878.2 21.7

Annotations:

YY
879.28 9.5
880.13 2.2
881.3 1.6
887.17 0.7
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B^{1,3}X_{NeuAc}
896.18 1.6

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C^{0,4}X_{HexNAc} C^{2,4}X_{HexNAc}
896.43 0.5

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C^{0,4}X_{HexNAc} C^{2,4}X_{HexNAc}
898.39 0.5
912.44 1.0

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C^{1,3}X_{NeuAc}
922.14 0.5

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ZZ
925.78 0.4
939.14 0.4

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ZZ
939.86 0.4

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YZ ZY
942.36 1.0

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Y^{1,5}X_{NeuAc}
957.44 0.6

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YZ ZY
958.26 0.5

Annotations:

YY
975.28 6.4

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YY
976.27 3.1

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^{2,5}X_{HexNAc}Z ^{0,2}X_{Fuc}Z
977.31 0.8

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Z^{0,3}X_{NeuAc} Y^{2,5}X_{HexNAc}
978.08 0.3

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^{0,2}X_{HexNAc}Y
984.01 0.4
985.33 1.0

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^{1,5}X_{HexNAc}Z
992.39 0.6

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^{2,5}X_{Fuc}Z
999.19 0.4
1001.89 0.6
1002.24 0.4
1003.31 0.4

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^{1,5}X_{HexNAc}Y Z^{0,4}X_{HexNAc} Z^{2,4}X_{HexNAc}
1010.2 0.3

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^{2,5}X_{Fuc}Y
1015.43 1.3
1021.23 0.7

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Y^{0,4}X_{HexNAc} Y^{2,4}X_{HexNAc}
1025.1 0.5
1027.15 0.6

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Z^{0,2}X_{NeuAc}
1032.22 1.9

Annotations:

YY
1032.92 0.8
1033.29 2.3
1034.18 1.3

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Z^{0,3}X_{NeuAc}
1034.5 0.9

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Z^{0,3}X_{NeuAc}
1040.36 1.4

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YY
1040.76 0.6

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YY
1050.23 0.6

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^{1,5}X_{Fuc}Z Z^{3,5}X_{NeuAc} Z^{1,5}X_{HexNAc}
1058.32 0.6

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^{0,2}X_{HexNAc}Y
1065.37 0.5
1080.31 0.4

Annotations:

Z
1080.8 0.5

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Z
1081.07 0.4

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Y
1098.52 1.6

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Y
1099.27 26.0

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Z^{1,3}X_{NeuAc}
1100.13 4.7

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Z^{2,5}X_{NeuAc} ^{0,4}X_{HexNAc}Z ^{2,4}X_{HexNAc}Z ^{1,3}X_{Fuc}Z ^{2,4}X_{Fuc}Z
1100.46 1.0

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Z^{2,5}X_{NeuAc} ^{0,4}X_{HexNAc}Z ^{2,4}X_{HexNAc}Z ^{1,3}X_{Fuc}Z ^{2,4}X_{Fuc}Z
1101.54 0.5

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Y^{0,4}X_{HexNAc} Y^{2,4}X_{HexNAc}
1108.44 0.4

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^{1,3}X_{Fuc}Z ^{2,4}X_{Fuc}Z
1114.18 0.5

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Z^{0,3}X_{NeuAc}
1116.62 0.6

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^{0,4}X_{Fuc}Z
1119.04 0.4
1125.86 0.5
1127.23 1.1
1148.9 0.7
1157.97 0.3

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^{1,4}X_{Fuc}Z
1158.19 0.4

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^{1,4}X_{Fuc}Z
1159.59 0.5
1160.09 2.8

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Z
1161.23 0.7

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Y
1162.18 0.6

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^{0,2}X_{Fuc}Y
1169.09 0.6

Annotations:

Y^{3,5}X_{HexNAc}
1176.05 2.5

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^{1,4}X_{Fuc}Y
1176.4 0.6

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^{1,4}X_{Fuc}Y
1177.19 2.4
1178.24 486.9

Annotations:

Y
1179.26 220.4
1180.23 89.9
1181.26 7.0

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Z^{1,3}X_{NeuAc}
1181.62 1.7

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Z^{1,3}X_{NeuAc}
1195.21 1.4
1204.39 0.8

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Z^{1,3}X_{NeuAc} ^{0,4}X_{Fuc}Z Z^{2,4}X_{NeuAc} Z^{1,3}X_{HexNAc}
1220.24 1.1
1221.25 1.5
1222.32 0.7

Annotations:

^{0,4}X_{Fuc}Y Y^{1,3}X_{NeuAc} Y^{2,4}X_{NeuAc} Y^{1,3}X_{HexNAc}
1230.75 0.5
1232.49 0.8
1248.01 0.5

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Z
1248.56 0.7

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Z
1249.99 0.8

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^{1,5}X_{NeuAc}
1261.22 1.2

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Z^{1,3}X_{NeuAc}
1262.51 0.9
1271.25 0.6

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^{1,5}X_{Fuc}
1287.89 0.4
1313.53 0.6
1319.32 0.4
1320.26 0.3

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