Efficient Chemoenzymatic Synthesis of an N-glycan Isomer Library
Peak | Intensity |
---|---|
310.11 | 7.5 |
Annotations: C |
|
312.93 | 12.4 |
330.02 | 5.9 |
Annotations: ^{1,4}X_{Man}Y Y^{1,4}X_{Man} |
|
364.78 | 3.8 |
366.17 | 1466.0 |
Annotations: YZ ZY BY BY CZ CZ BY BY CZ CZ YZ ZY |
|
367.19 | 49.1 |
381.18 | 7.6 |
407.22 | 7.3 |
Annotations: Z |
|
425.43 | 10.1 |
Annotations: Y |
|
452.68 | 4.4 |
Annotations: ^{1,5}X_{Man} |
|
454.18 | 313.9 |
Annotations: B B |
|
455.27 | 6.0 |
Annotations: ^{1,4}A_{Man} ^{0,3}A_{Man} |
|
458.34 | 5.9 |
Annotations: ZZ ZZ |
|
505.95 | 5.7 |
Annotations: ^{2,5}X_{Gal}Y ^{2,5}X_{GlcNAc}Y Y^{2,5}X_{Gal} |
|
526.39 | 8.4 |
528.3 | 369.4 |
Annotations: BY BY CZ CZ |
|
529.25 | 23.5 |
549.14 | 41.9 |
Annotations: YZ ZY YZ ZY YZ ZY YZ ZY |
|
569.31 | 19.9 |
Annotations: YZ ZY |
|
585.8 | 9.6 |
Annotations: B^{1,5}X_{GlcNAc} |
|
586.49 | 11.7 |
Annotations: B^{1,5}X_{GlcNAc} ^{2,5}X_{Gal}Y Y^{2,5}X_{Gal} |
|
587.37 | 31.4 |
Annotations: YY |
|
616.28 | 24.4 |
Annotations: C^{0,2}X_{NeuAc} C^{0,2}X_{NeuAc} |
|
629.79 | 55.5 |
Annotations: YZ ZY YZ ZY |
|
639.29 | 35.5 |
640.32 | 17.2 |
656.39 | 117.9 |
657.25 | 7360.1 |
Annotations: B B |
|
658.3 | 809.4 |
689.4 | 9.4 |
Annotations: ^{1,3}X_{Man}Y Y^{1,3}X_{Man} |
|
690.28 | 374.4 |
691.31 | 59.4 |
694.23 | 16.2 |
Annotations: Z Z |
|
708.31 | 24.5 |
710.84 | 26.5 |
731.33 | 295.5 |
Annotations: YZ ZY YZ ZY YZ ZY YZ ZY |
|
732.3 | 27.4 |
Annotations: C^{2,5}X_{GlcNAc} |
|
740.16 | 11.7 |
Annotations: YY YY |
|
748.07 | 18.1 |
749.2 | 375.9 |
Annotations: YY YY |
|
750.26 | 34.7 |
775.23 | 32.1 |
Annotations: Z Z |
|
784.37 | 15.3 |
Annotations: Y Y |
|
803.83 | 16.0 |
Annotations: B^{2,5}X_{Gal} B^{2,5}X_{Gal} |
|
811.75 | 10.9 |
Annotations: B^{1,4}X_{Gal} B^{1,4}X_{Gal} |
|
818.47 | 19.8 |
819.33 | 291.1 |
Annotations: B B |
|
820.43 | 66.3 |
Annotations: ^{1,4}X_{GlcNAc} C^{1,4}X_{Gal} C^{1,4}X_{Gal} |
|
821.69 | 112.1 |
Annotations: YY |
|
835.69 | 14.4 |
Annotations: C^{1,3}X_{Gal} C^{2,4}X_{Gal} C^{1,3}X_{Gal} C^{2,4}X_{Gal} ^{2,4}X_{NeuAc}Y Y^{2,4}X_{NeuAc} |
|
847.87 | 8.2 |
Annotations: ^{1,5}X_{NeuAc}Z Z^{1,5}X_{NeuAc} ^{2,5}X_{GlcNAc}Y |
|
850.32 | 6.4 |
852.39 | 56.5 |
853.3 | 12.4 |
856.6 | 85.8 |
Annotations: BY BY CZ CZ |
|
860.43 | 3.9 |
Annotations: ^{3,5}X_{GlcNAc}Z |
|
861.45 | 8.0 |
870.44 | 8.0 |
Annotations: ^{3,5}X_{NeuAc}Z Z^{3,5}X_{NeuAc} |
|
876.99 | 15.6 |
Annotations: Z Z |
|
878.42 | 10.9 |
Annotations: B^{1,3}X_{NeuAc} B^{1,3}X_{NeuAc} ^{3,5}X_{GlcNAc}Y |
|
885.8 | 32.9 |
Annotations: Y Y |
|
892.24 | 31.3 |
Annotations: B^{1,5}X_{NeuAc} B^{1,5}X_{NeuAc} ^{2,4}X_{GlcNAc}Y |
|
893.32 | 734.5 |
Annotations: YZ ZY |
|
894.38 | 101.5 |
910.21 | 28.7 |
911.4 | 883.5 |
Annotations: YY |
|
912.25 | 119.2 |
930.69 | 9.1 |
934.4 | 5.3 |
Annotations: YZ ZY YZ ZY |
|
935.44 | 25.8 |
Annotations: ^{1,3}X_{NeuAc}Z Z^{1,3}X_{NeuAc} |
|
948.51 | 103.5 |
949.35 | 22.1 |
952.68 | 29.6 |
Annotations: YY YY |
|
957.91 | 146.0 |
Annotations: Z Z |
|
966.16 | 28.6 |
967.12 | 453.9 |
Annotations: Y Y |
|
967.67 | 59.1 |
970.53 | 10.8 |
973.88 | 10.9 |
981.39 | 24.0 |
Annotations: BY BY CZ CZ |
|
1001.92 | 14.7 |
Annotations: B |
|
1002.84 | 8.4 |
Annotations: ^{1,5}X_{NeuAc} ^{1,5}X_{NeuAc} |
|
1022.53 | 14.9 |
Annotations: ^{3,5}X_{GlcNAc}Z |
|
1023.48 | 41.9 |
1030.35 | 11.4 |
1040.34 | 27.9 |
Annotations: ^{3,5}X_{GlcNAc}Y |
|
1041.3 | 13.3 |
1055.43 | 730.2 |
1056.54 | 81.0 |
1073.54 | 32.5 |
1078.42 | 6.1 |
Annotations: ZZ ZZ ZZ ZZ |
|
1093.48 | 9.4 |
1095.85 | 40.9 |
1096.53 | 195.4 |
Annotations: YZ ZY YZ ZY YZ ZY YZ ZY |
|
1097.49 | 30.4 |
Annotations: ^{1,5}A_{Man}Z ^{1,5}A_{Man}Z |
|
1112.04 | 13.5 |
1113.47 | 15.0 |
1114.48 | 254.5 |
Annotations: YY YY YY YY |
|
1115.34 | 62.3 |
Annotations: ^{1,5}A_{Man}Y ^{1,5}A_{Man}Y |
|
1165.34 | 5.7 |
1183.8 | 8.1 |
1184.49 | 195.2 |
Annotations: CZ CZ BY BY |
|
1185.45 | 87.3 |
1202.56 | 98.3 |
Annotations: CY CY |
|
1203.37 | 26.6 |
1217.6 | 20.6 |
1218.29 | 4.0 |
1240.41 | 12.9 |
Annotations: ZZ ZZ |
|
1243.42 | 20.8 |
Annotations: ^{3,5}X_{GlcNAc}Y |
|
1257.92 | 27.4 |
Annotations: ^{2,4}X_{GlcNAc}Y |
|
1258.5 | 667.8 |
Annotations: YZ ZY YZ ZY |
|
1259.52 | 171.8 |
1274.8 | 8.1 |
Annotations: C^{1,4}X_{Man} C^{0,3}X_{GlcNAc} C^{1,4}X_{Man} |
|
1275.55 | 72.9 |
1276.5 | 1998.8 |
Annotations: YY YY |
|
1277.49 | 711.4 |
1278.33 | 3.7 |
1313.71 | 4.4 |
1329.32 | 12.7 |
1345.7 | 43.7 |
Annotations: Y^{1,5}X_{Gal} ^{1,5}X_{Gal}Y |
|
1346.55 | 879.2 |
Annotations: BY BY CZ CZ BY BY CZ CZ |
|
1347.55 | 267.1 |
1364.41 | 55.5 |
Annotations: CY CY CY CY |
|
1366.62 | 7.0 |
1369.46 | 36.0 |
1385.46 | 8.2 |
1387.57 | 454.0 |
Annotations: Z Z |
|
1388.52 | 59.6 |
Annotations: B^{0,2}X_{Gal} B^{0,2}X_{Gal} |
|
1402.96 | 15.6 |
1404.34 | 121.0 |
Annotations: B^{2,5}X_{Gal} B^{2,5}X_{Gal} |
|
1405.02 | 38.7 |
Annotations: Y Y |
|
1405.53 | 1766.6 |
Annotations: Y Y |
|
1406.59 | 761.9 |
Annotations: C^{0,2}X_{Gal} C^{0,2}X_{Gal} |
|
1407.62 | 9.7 |
1420.62 | 65.0 |
1421.78 | 43.5 |
1438.58 | 52.0 |
1439.84 | 15.6 |
1461.72 | 6.0 |
Annotations: YZ ZY YZ ZY |
|
1462.73 | 21.7 |
Annotations: ^{1,5}A_{Man}Z ^{1,5}A_{Man}Z |
|
1474.51 | 19.6 |
1475.58 | 5.2 |
Annotations: B^{3,5}X_{GlcNAc} |
|
1479.58 | 147.3 |
Annotations: YY YY |
|
1480.74 | 13.7 |
Annotations: ^{1,5}A_{Man}Y ^{1,5}A_{Man}Y |
|
1508.64 | 38.7 |
Annotations: CZ CZ BY BY |
|
1509.63 | 6.1 |
1528.06 | 11.4 |
1531.71 | 12.8 |
Annotations: BZ BZ |
|
1532.71 | 6.4 |
1548.76 | 10.3 |
1549.61 | 1771.0 |
Annotations: Z Z |
|
1550.61 | 561.1 |
1564.9 | 24.9 |
1565.87 | 103.3 |
Annotations: ^{2,5}X_{NeuAc}Y Y^{2,5}X_{NeuAc} |
|
1566.59 | 255.7 |
1567.54 | 7782.9 |
Annotations: Y Y |
|
1568.58 | 2834.2 |
1569.23 | 108.4 |
1570.05 | 16.9 |
1623.64 | 26.3 |
Annotations: YZ ZY |
|
1637.55 | 68.7 |
Annotations: ^{1,4}X_{NeuAc}Z Z^{1,4}X_{NeuAc} |
|
1641.76 | 165.9 |
Annotations: YY |
|
1642.57 | 12.3 |
Annotations: C^{3,5}X_{NeuAc} C^{3,5}X_{NeuAc} |
|
1696.75 | 23.5 |
Annotations: ^{3,5}X_{GlcNAc} |
|
1711.7 | 104.0 |
Annotations: BY BY CZ CZ |
|
1728.47 | 44.1 |
1729.69 | 53.1 |
Annotations: CY CY |
|
1730.52 | 4.5 |
1752.78 | 53.8 |
Annotations: Z Z |
|
1753.81 | 18.0 |
1768.92 | 19.8 |
1770.79 | 139.7 |
Annotations: Y Y |
|
1771.81 | 53.6 |
Annotations: ^{1,5}A_{Man} |
|
1799.68 | 36.1 |
Annotations: B |
|
1800.63 | 11.4 |
1840.63 | 54.5 |
1841.75 | 25.9 |
1856.97 | 16.0 |
1858.68 | 172.2 |
1859.8 | 80.7 |
1914.61 | 10.2 |
Annotations: Z Z |
|
1915.83 | 29.0 |
1932.72 | 277.9 |
Annotations: Y Y |
|
1933.75 | 157.9 |