Efficient Chemoenzymatic Synthesis of an N-glycan Isomer Library

PubMed Entry

Peak Intensity
310.11 7.5

Annotations:

C
312.93 12.4
330.02 5.9

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^{1,4}X_{Man}Y Y^{1,4}X_{Man}
364.78 3.8
366.17 1466.0

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YZ ZY BY BY CZ CZ BY BY CZ CZ YZ ZY
367.19 49.1
381.18 7.6
407.22 7.3

Annotations:

Z
425.43 10.1

Annotations:

Y
452.68 4.4

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^{1,5}X_{Man}
454.18 313.9

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B B
455.27 6.0

Annotations:

^{1,4}A_{Man} ^{0,3}A_{Man}
458.34 5.9

Annotations:

ZZ ZZ
505.95 5.7

Annotations:

^{2,5}X_{Gal}Y ^{2,5}X_{GlcNAc}Y Y^{2,5}X_{Gal}
526.39 8.4
528.3 369.4

Annotations:

BY BY CZ CZ
529.25 23.5
549.14 41.9

Annotations:

YZ ZY YZ ZY YZ ZY YZ ZY
569.31 19.9

Annotations:

YZ ZY
585.8 9.6

Annotations:

B^{1,5}X_{GlcNAc}
586.49 11.7

Annotations:

B^{1,5}X_{GlcNAc} ^{2,5}X_{Gal}Y Y^{2,5}X_{Gal}
587.37 31.4

Annotations:

YY
616.28 24.4

Annotations:

C^{0,2}X_{NeuAc} C^{0,2}X_{NeuAc}
629.79 55.5

Annotations:

YZ ZY YZ ZY
639.29 35.5
640.32 17.2
656.39 117.9
657.25 7360.1

Annotations:

B B
658.3 809.4
689.4 9.4

Annotations:

^{1,3}X_{Man}Y Y^{1,3}X_{Man}
690.28 374.4
691.31 59.4
694.23 16.2

Annotations:

Z Z
708.31 24.5
710.84 26.5
731.33 295.5

Annotations:

YZ ZY YZ ZY YZ ZY YZ ZY
732.3 27.4

Annotations:

C^{2,5}X_{GlcNAc}
740.16 11.7

Annotations:

YY YY
748.07 18.1
749.2 375.9

Annotations:

YY YY
750.26 34.7
775.23 32.1

Annotations:

Z Z
784.37 15.3

Annotations:

Y Y
803.83 16.0

Annotations:

B^{2,5}X_{Gal} B^{2,5}X_{Gal}
811.75 10.9

Annotations:

B^{1,4}X_{Gal} B^{1,4}X_{Gal}
818.47 19.8
819.33 291.1

Annotations:

B B
820.43 66.3

Annotations:

^{1,4}X_{GlcNAc} C^{1,4}X_{Gal} C^{1,4}X_{Gal}
821.69 112.1

Annotations:

YY
835.69 14.4

Annotations:

C^{1,3}X_{Gal} C^{2,4}X_{Gal} C^{1,3}X_{Gal} C^{2,4}X_{Gal} ^{2,4}X_{NeuAc}Y Y^{2,4}X_{NeuAc}
847.87 8.2

Annotations:

^{1,5}X_{NeuAc}Z Z^{1,5}X_{NeuAc} ^{2,5}X_{GlcNAc}Y
850.32 6.4
852.39 56.5
853.3 12.4
856.6 85.8

Annotations:

BY BY CZ CZ
860.43 3.9

Annotations:

^{3,5}X_{GlcNAc}Z
861.45 8.0
870.44 8.0

Annotations:

^{3,5}X_{NeuAc}Z Z^{3,5}X_{NeuAc}
876.99 15.6

Annotations:

Z Z
878.42 10.9

Annotations:

B^{1,3}X_{NeuAc} B^{1,3}X_{NeuAc} ^{3,5}X_{GlcNAc}Y
885.8 32.9

Annotations:

Y Y
892.24 31.3

Annotations:

B^{1,5}X_{NeuAc} B^{1,5}X_{NeuAc} ^{2,4}X_{GlcNAc}Y
893.32 734.5

Annotations:

YZ ZY
894.38 101.5
910.21 28.7
911.4 883.5

Annotations:

YY
912.25 119.2
930.69 9.1
934.4 5.3

Annotations:

YZ ZY YZ ZY
935.44 25.8

Annotations:

^{1,3}X_{NeuAc}Z Z^{1,3}X_{NeuAc}
948.51 103.5
949.35 22.1
952.68 29.6

Annotations:

YY YY
957.91 146.0

Annotations:

Z Z
966.16 28.6
967.12 453.9

Annotations:

Y Y
967.67 59.1
970.53 10.8
973.88 10.9
981.39 24.0

Annotations:

BY BY CZ CZ
1001.92 14.7

Annotations:

B
1002.84 8.4

Annotations:

^{1,5}X_{NeuAc} ^{1,5}X_{NeuAc}
1022.53 14.9

Annotations:

^{3,5}X_{GlcNAc}Z
1023.48 41.9
1030.35 11.4
1040.34 27.9

Annotations:

^{3,5}X_{GlcNAc}Y
1041.3 13.3
1055.43 730.2
1056.54 81.0
1073.54 32.5
1078.42 6.1

Annotations:

ZZ ZZ ZZ ZZ
1093.48 9.4
1095.85 40.9
1096.53 195.4

Annotations:

YZ ZY YZ ZY YZ ZY YZ ZY
1097.49 30.4

Annotations:

^{1,5}A_{Man}Z ^{1,5}A_{Man}Z
1112.04 13.5
1113.47 15.0
1114.48 254.5

Annotations:

YY YY YY YY
1115.34 62.3

Annotations:

^{1,5}A_{Man}Y ^{1,5}A_{Man}Y
1165.34 5.7
1183.8 8.1
1184.49 195.2

Annotations:

CZ CZ BY BY
1185.45 87.3
1202.56 98.3

Annotations:

CY CY
1203.37 26.6
1217.6 20.6
1218.29 4.0
1240.41 12.9

Annotations:

ZZ ZZ
1243.42 20.8

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^{3,5}X_{GlcNAc}Y
1257.92 27.4

Annotations:

^{2,4}X_{GlcNAc}Y
1258.5 667.8

Annotations:

YZ ZY YZ ZY
1259.52 171.8
1274.8 8.1

Annotations:

C^{1,4}X_{Man} C^{0,3}X_{GlcNAc} C^{1,4}X_{Man}
1275.55 72.9
1276.5 1998.8

Annotations:

YY YY
1277.49 711.4
1278.33 3.7
1313.71 4.4
1329.32 12.7
1345.7 43.7

Annotations:

Y^{1,5}X_{Gal} ^{1,5}X_{Gal}Y
1346.55 879.2

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BY BY CZ CZ BY BY CZ CZ
1347.55 267.1
1364.41 55.5

Annotations:

CY CY CY CY
1366.62 7.0
1369.46 36.0
1385.46 8.2
1387.57 454.0

Annotations:

Z Z
1388.52 59.6

Annotations:

B^{0,2}X_{Gal} B^{0,2}X_{Gal}
1402.96 15.6
1404.34 121.0

Annotations:

B^{2,5}X_{Gal} B^{2,5}X_{Gal}
1405.02 38.7

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Y Y
1405.53 1766.6

Annotations:

Y Y
1406.59 761.9

Annotations:

C^{0,2}X_{Gal} C^{0,2}X_{Gal}
1407.62 9.7
1420.62 65.0
1421.78 43.5
1438.58 52.0
1439.84 15.6
1461.72 6.0

Annotations:

YZ ZY YZ ZY
1462.73 21.7

Annotations:

^{1,5}A_{Man}Z ^{1,5}A_{Man}Z
1474.51 19.6
1475.58 5.2

Annotations:

B^{3,5}X_{GlcNAc}
1479.58 147.3

Annotations:

YY YY
1480.74 13.7

Annotations:

^{1,5}A_{Man}Y ^{1,5}A_{Man}Y
1508.64 38.7

Annotations:

CZ CZ BY BY
1509.63 6.1
1528.06 11.4
1531.71 12.8

Annotations:

BZ BZ
1532.71 6.4
1548.76 10.3
1549.61 1771.0

Annotations:

Z Z
1550.61 561.1
1564.9 24.9
1565.87 103.3

Annotations:

^{2,5}X_{NeuAc}Y Y^{2,5}X_{NeuAc}
1566.59 255.7
1567.54 7782.9

Annotations:

Y Y
1568.58 2834.2
1569.23 108.4
1570.05 16.9
1623.64 26.3

Annotations:

YZ ZY
1637.55 68.7

Annotations:

^{1,4}X_{NeuAc}Z Z^{1,4}X_{NeuAc}
1641.76 165.9

Annotations:

YY
1642.57 12.3

Annotations:

C^{3,5}X_{NeuAc} C^{3,5}X_{NeuAc}
1696.75 23.5

Annotations:

^{3,5}X_{GlcNAc}
1711.7 104.0

Annotations:

BY BY CZ CZ
1728.47 44.1
1729.69 53.1

Annotations:

CY CY
1730.52 4.5
1752.78 53.8

Annotations:

Z Z
1753.81 18.0
1768.92 19.8
1770.79 139.7

Annotations:

Y Y
1771.81 53.6

Annotations:

^{1,5}A_{Man}
1799.68 36.1

Annotations:

B
1800.63 11.4
1840.63 54.5
1841.75 25.9
1856.97 16.0
1858.68 172.2
1859.8 80.7
1914.61 10.2

Annotations:

Z Z
1915.83 29.0
1932.72 277.9

Annotations:

Y Y
1933.75 157.9

There are 3 similar spectra:

Id Structure Score

2703

0.98

2754

0.90

2733

0.86
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