Efficient Chemoenzymatic Synthesis of an N-glycan Isomer Library

PubMed Entry

Peak Intensity
163.1 38.2

Annotations:

B
168.05 43.2
182.9 0.6
184.14 0.3

Annotations:

Y
185.12 6.3
186.07 2077.2

Annotations:

BZ ZZ
187.14 204.5
188.12 1.2
195.99 0.4
199.03 0.5
200.09 0.3
200.8 0.1
202.03 22.2
202.78 85.2
204.01 52364.3

Annotations:

B
205.06 3244.8

Annotations:

^{1,3}A_{Man}Z ^{2,4}A_{Man}Z
205.92 38.2

Annotations:

^{2,5}A_{Man}Z
206.45 5.6

Annotations:

^{2,5}A_{Man}Z
207.16 0.3
208.09 24.0
209.04 0.8
210.42 0.6
213.94 0.1

Annotations:

^{2,4}A_{Man} ^{1,3}A_{Man} ^{0,2}A_{Man}Z
217.1 1.6
218.01 0.8
219.0 22.0
220.19 0.3
221.19 11.0

Annotations:

^{1,5}A_{Man}Z
222.12 1560.0

Annotations:

C
223.05 34.0

Annotations:

^{0,2}A_{Man}Y ^{0,4}A_{Man} ^{1,3}A_{Man}Y ^{2,4}A_{Man}Y
223.98 1.2
227.25 0.8
228.01 47.0
229.05 9.8

Annotations:

^{1,4}A_{Man}
230.1 0.9

Annotations:

^{1,5}A_{Man}Y
232.1 0.3
233.31 0.1
234.83 0.4

Annotations:

BZ
235.97 0.1
237.04 0.4

Annotations:

^{3,5}A_{Man}
238.19 1.0
239.09 0.1
240.08 1.6
241.12 1.1
242.97 0.1
244.0 1.8

Annotations:

BY CZ
244.92 0.5
245.99 13.1
247.19 0.5
250.01 0.5
252.09 0.2
253.46 0.1

Annotations:

CY
254.21 0.3
255.11 0.5

Annotations:

BZ BZ
255.63 82.1

Annotations:

BZ BZ
257.95 0.2
259.16 0.2
260.07 0.4
261.11 0.5
262.14 0.6
263.16 1.2
263.89 0.1

Annotations:

^{1,3}A_{Man}
265.17 0.2
267.06 8.8
267.99 0.2
269.06 1.2
270.1 66.6
272.34 62.3
275.12 0.1
276.11 0.4
278.15 0.4
279.1 0.1
280.26 0.1
283.54 0.5
284.12 1.6
285.13 0.5
286.08 1.0

Annotations:

Y
287.07 1.3
288.21 12.1
290.04 4.0
291.14 79.9
292.13 0.2
294.09 1.9

Annotations:

^{1,4}A_{Man}
294.83 0.1
296.1 25.3
296.95 3.8
299.98 0.9
300.99 0.3
302.1 0.3
305.14 0.2
306.02 3.6
307.26 4.5

Annotations:

BZ
308.23 2.1
309.03 44.0
309.73 0.4
310.9 0.3
312.27 0.3
312.98 5.4
314.04 2.2
314.61 819.9
315.2 5.4
315.99 1.5
317.75 1.6
318.99 29.8
320.2 1.6
321.0 0.5
321.94 24.4
324.1 0.9
324.82 61.6

Annotations:

BY CZ
326.11 28.3
327.12 21.7
328.05 1.2
329.01 1.9
330.17 66.1
331.27 6.0

Annotations:

^{1,5}A_{Man}
332.17 10.8
333.1 0.3
334.16 0.5
336.95 0.6

Annotations:

BZ
338.22 1.1

Annotations:

^{1,5}A_{Man}
338.98 0.8
340.18 0.5
341.05 0.1
341.9 1.6
342.61 28.5
343.2 54.4

Annotations:

CY
344.52 1.1
345.95 0.1

Annotations:

B
347.09 7.0
348.1 146.6
348.73 13.7

Annotations:

ZZ
349.27 135.2

Annotations:

ZZ
350.14 9012.9

Annotations:

Z
351.11 1211.9
351.66 45.4
353.17 0.6
354.0 1.0
355.82 1.0
357.01 0.6

Annotations:

BZ ZZ
358.27 0.6

Annotations:

YZ ZY
359.04 3.3
359.97 1.8
360.87 0.1
363.1 2.0
363.93 56.8
364.53 1.1
365.22 25.1
366.15 9833.2

Annotations:

B
367.25 1231.0

Annotations:

YY
368.16 1198.0

Annotations:

Y
369.14 161.4
370.05 1.3
371.03 0.4
373.4 0.7
374.08 0.2
375.15 5.8

Annotations:

CY YY
376.02 0.4
377.15 2.6
378.07 0.7
380.1 0.1
382.12 0.2
383.16 0.6
384.15 168.7

Annotations:

C
384.89 1.2
385.92 0.3
386.76 123.3
387.72 388.8
388.31 0.4
389.11 0.1

Annotations:

ZZ
390.21 0.6
392.26 2.1
393.52 2.4
394.85 9.9
395.76 2434.2
396.75 146.8
398.16 0.9
399.07 1.2
400.15 0.8
401.03 0.7
402.14 1.7
402.98 9.5
404.18 7.1
405.29 5.8
406.04 2.2
407.19 379.4

Annotations:

YZ ZY
408.27 65.9
409.18 2.4
410.17 0.5
411.07 0.9

Annotations:

^{2,5}A_{Man}Z
411.92 0.7
413.16 1.7
414.21 3.1
415.04 0.6
417.27 0.9
421.31 5.8
422.15 0.5
422.75 30.5
423.78 0.3
424.44 55.9
425.23 1654.9

Annotations:

YY
426.27 256.4

Annotations:

^{1,3}A_{Man} ^{2,4}A_{Man}
427.0 233.0

Annotations:

^{0,2}A_{Man}Z
428.0 28.8
429.02 5.6

Annotations:

^{2,5}A_{Man}Y
430.32 5.8

Annotations:

ZZ
431.45 1.9
432.12 0.6
434.08 1.8
435.18 4.2
436.22 2.9
437.2 0.7
438.2 35.7

Annotations:

ZZ
438.97 0.9

Annotations:

Z
439.57 166.9

Annotations:

Z
440.15 2.9
441.22 1.9

Annotations:

^{1,5}A_{Man}Z
442.11 2.3
442.98 1.1
443.84 0.8
445.23 0.9

Annotations:

^{0,2}A_{Man}Y
446.13 0.8
447.32 772.5

Annotations:

B
448.15 26.7

Annotations:

Y
449.07 0.6
450.24 10.7
451.13 7.0
452.13 4.8
453.03 0.2
454.26 0.6
455.2 0.7
456.33 272.2

Annotations:

C
456.91 14.3
457.95 0.9
458.51 3.5

Annotations:

ZZ
459.58 6.6

Annotations:

^{1,5}A_{Man}Y
460.27 0.6
461.27 1.2
462.16 0.6
463.17 0.6
464.32 0.5
465.03 0.3
466.12 13.7
467.11 5.3
467.85 2499.0

Annotations:

YZ ZY
468.8 671.4

Annotations:

BZ
469.45 33.1

Annotations:

BZ
470.44 56.9
471.38 4.6
471.99 1.1
472.95 1.5
474.22 1.7
474.87 0.4
475.47 40.4
476.78 7536.8

Annotations:

YY
477.56 719.8
478.58 2.4
479.24 7.1
479.81 58.3
480.32 0.6
481.03 0.6
481.87 1.3
482.79 30.3
483.38 15.9
484.19 1.1
485.09 1.8
485.82 7.8
486.4 3.1
486.97 105.0

Annotations:

BY CZ
487.93 62.4
488.64 0.9
489.16 0.6
490.25 3.7
492.11 4.0
492.9 1.0
494.28 18.7
494.99 6.8
495.96 0.7
496.7 3.1
497.31 0.3
498.26 8.9
499.04 2.1
500.11 6.8
501.18 3.0
501.95 2.6
502.48 1.6
502.99 0.3
503.71 1.1
504.77 43.0

Annotations:

CY
505.61 7.7

Annotations:

CY
507.35 1.9
508.4 1.0
509.17 18.9
510.22 135.8

Annotations:

BZ BZ
511.17 28.5
512.17 867.9
513.27 259.6
513.96 1.4
514.97 4.5
516.19 3.1
517.23 2.0
518.42 23.0
519.51 1.5
520.23 827.6

Annotations:

Z
520.74 4.2
521.3 1.3
521.95 1.6
522.95 0.2
524.27 1.3
525.58 4.3
526.38 65.9
527.23 131.5
528.19 15331.4

Annotations:

BY CZ BY CZ
529.18 2210.0

Annotations:

Y
530.23 239.8
531.16 1.3
532.04 12.1
533.08 12.6
534.21 22.5
535.28 64.4
536.35 2.0
536.94 0.8
537.61 47.0
538.24 21.6
539.08 19.9
539.77 47.5
540.99 518.6

Annotations:

Z
542.18 2.8
543.24 0.6
544.35 0.3
545.07 0.3
546.14 81.3

Annotations:

CY CY
547.76 46.9
548.89 3717.2

Annotations:

Z
549.8 1730.0

Annotations:

Y
550.44 18.8
551.24 35.4
552.01 1.1
553.36 72.3

Annotations:

Z
554.09 4.4
554.91 0.3
556.18 1.0
556.82 321.5
557.78 7131.9

Annotations:

Y
558.3 383.7
559.61 38.3
560.21 2.0
561.15 0.5
561.74 2.4
562.73 10.5
563.6 7.2
566.09 1.3
566.68 13.5
567.4 0.8
568.3 97.4
569.28 693.5
570.23 229.6
571.29 419.0

Annotations:

Y
572.23 91.5
573.28 1.5
573.99 1.7
574.89 1.4
575.6 0.9
576.3 1.1
576.87 5.8
578.28 2.6
579.37 1.6
580.11 10.1
581.29 0.7
582.05 0.4
582.98 2.4
583.98 10.8
585.04 10.9
586.1 138.9
587.22 4384.0
588.19 647.0
588.88 58.9
589.74 3.4
590.43 2.1
591.39 1.8
592.43 2.4
594.03 4.0
595.16 6.4
596.22 8.7
597.31 2.0
598.17 2.7
599.32 3.7
599.88 0.5
601.03 14.3
602.3 4.0
603.44 21.1
604.56 5.9
605.3 2.1
605.84 0.7
606.5 4.6
607.34 5.3
608.14 5.1
608.73 1.6
610.33 31.8
611.31 26.3
612.28 38.3
613.1 118.9
614.13 15.2
615.17 12.3
616.61 1.9
618.41 1.1
620.01 2.3
621.02 92.9
621.82 220.1
622.46 75.7
623.35 3.2
628.47 42.8
629.47 3.7
630.24 22.4
632.05 1.4

Annotations:

^{2,5}A_{Man}
632.74 0.7
637.09 1.1
638.19 49.9
639.31 71.4
648.85 0.3
650.76 63.1
651.42 25.3
652.01 0.5
652.66 0.4
654.16 1.2
656.39 37.4
662.35 13.7

Annotations:

^{1,5}A_{Man}
670.66 0.5
672.4 135.1

Annotations:

BZ
673.03 6.5
673.55 0.6
674.26 4963.7
675.3 833.5
676.24 3.3
679.01 2.5
679.62 2.8
680.28 1.0
687.94 69.3
689.02 414.2
689.63 0.6
690.24 24420.4

Annotations:

B
691.28 5193.5
692.27 268.8
692.91 84.9
694.41 0.2
695.53 0.6
696.37 4.7
707.55 4.7
708.31 231.4

Annotations:

C
709.33 126.4
710.34 9.7
711.32 3.9
712.31 0.1
713.24 57.2

Annotations:

BZ ZZ
714.38 26.7
715.38 142.3

Annotations:

ZY YZ
716.23 57.1
716.88 1.6
729.28 1.6
729.92 72.3
730.45 1.8
731.28 4697.3

Annotations:

BY CZ YZ ZY
732.34 1198.5
733.31 2845.6

Annotations:

YY
734.3 393.8
734.85 0.6
735.43 0.2
737.9 0.1
746.63 46.9
747.56 222.6
748.57 667.2
749.28 19982.4

Annotations:

CY YY
750.28 4326.8
751.09 184.9
752.11 5.9
760.33 0.5
763.22 1.8
769.09 0.7
771.34 0.4
772.4 26.6
773.38 20.5
774.29 58.0
775.24 50.7
775.81 0.3
777.22 0.1
781.34 0.4
782.24 1.0
787.22 0.5
788.22 1.0
789.48 5.6
790.32 948.5
791.28 62.3
791.87 0.6
794.9 1.8
797.35 0.4
800.43 0.5
803.2 0.2
810.41 0.2
815.48 1.4
816.15 3.5
817.6 10.1
818.27 93.6
822.21 0.5
825.69 15.8
831.05 0.1
833.74 1.2
834.54 157.3
835.56 173.3
836.3 12869.8
837.32 3623.1
838.2 291.3
838.73 0.6
839.81 28.8
841.46 0.1
842.27 0.6
844.21 0.3
849.45 0.9
851.67 1.8
852.49 3.6
853.52 0.9
854.32 234.2
855.41 5.4
856.22 3.0
857.32 25.7
859.17 1.4

Annotations:

ZZ
863.43 0.3
871.34 1.4
872.85 10.4
873.73 15.9
874.5 1.1
875.31 17.7

Annotations:

ZZ
875.82 0.3
876.39 220.3
877.35 5590.4

Annotations:

Z
878.34 1638.5
879.37 120.4
889.26 0.3
890.51 0.2
891.44 45.9
892.23 168.3
893.34 11945.2

Annotations:

B
894.43 3584.8
895.3 32744.9

Annotations:

Y
896.32 6794.4
897.23 294.6
898.43 42.2
906.44 0.1
908.08 0.4
908.97 31.9
909.93 258.4
910.64 731.5
911.31 38278.6

Annotations:

C
912.34 8615.8
913.25 449.0
915.22 0.6
916.19 0.2

Annotations:

ZZ
917.38 1.5
920.13 0.5
931.31 4.1
933.27 5.8
934.42 179.5

Annotations:

YZ ZY
935.36 1.1
936.2 23.6
937.49 89.0
938.01 0.2
940.61 1.5
950.44 0.4
951.02 59.4
952.43 302.6

Annotations:

YY
953.38 107.9
954.41 2.1
954.99 0.1
956.25 33.2
958.2 0.5
963.47 0.3
964.4 0.6
990.37 0.3
991.27 0.4
997.31 0.2
998.18 1.3
999.34 0.1
1000.34 0.1
1003.47 33.1
1004.21 1.1
1005.4 2.3
1006.47 0.5
1015.53 0.2
1017.43 0.2
1019.45 0.4
1020.7 0.1
1021.37 7.2
1022.41 39.9
1029.45 0.2
1030.18 1.0
1031.28 2.4
1032.26 1.1
1033.36 0.3
1036.38 0.7
1037.56 6.8
1038.43 555.2
1039.36 13878.2

Annotations:

Z
1040.39 4127.6
1041.39 255.7
1045.24 0.5
1054.1 48.3
1054.77 50.0
1055.35 1207.4
1056.42 5527.7
1057.34 120241.6

Annotations:

Y
1058.35 42910.9
1059.38 2492.7
1059.99 170.8
1060.56 8.0
1061.36 0.3
1062.15 17.7
1066.55 1.7
1071.4 0.9
1072.46 49.6
1074.38 11.3
1075.43 14.0
1077.31 1.5
1078.49 0.5
1080.35 0.5

Annotations:

Z
1081.4 0.2
1082.41 0.3
1087.23 2.2
1091.88 0.6
1093.4 3.0
1095.83 1.0
1096.46 154.6

Annotations:

Z
1097.37 96.3
1098.47 2.1

Annotations:

Y
1099.44 17.9
1108.23 0.2
1113.48 32.3
1114.43 496.3

Annotations:

Y
1115.49 308.2
1116.42 41.4
1125.36 0.7
1126.64 0.7
1127.31 0.9
1129.27 0.5
1136.53 2.0
1151.14 0.2
1156.31 0.4
1178.54 0.2
1181.49 0.9
1222.42 0.1
1224.22 0.6
1237.5 0.2
1238.59 0.9
1239.57 0.3
1240.42 0.5
1241.38 0.7

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