Recombinant mucin-type fusion proteins with Galα1,3Gal substitution as Clostridium difficile toxin A inhibitors

PubMed Entry

GlyToucan Accession Number: G99730GF

Peak Intensity
290.16 2.4

Annotations:

B
377.22 4.1
378.32 2.4

Annotations:

B^{3,5}X_{Gal} ^{0,2}A_{GalNAc}Z B^{1,5}X_{GlcNAc} B^{1,5}X_{Gal} B^{0,4}X_{Gal} B^{0,4}X_{GlcNAc} ^{0,2}X_{GlcNAc} ^{0,4}X_{NeuAc}Y
427.07 2.4
517.23 3.2

Annotations:

Y^{0,2}X_{GlcNAc} Z^{1,3}X_{Gal} Z^{2,4}X_{Gal} ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z ^{1,3}X_{GalNAc}Z
519.4 2.6

Annotations:

Y
582.0 2.2

Annotations:

B^{0,2}X_{NeuAc} ^{3,5}A_{GlcNAc}Z ^{3,5}A_{GlcNAc}Z ^{1,5}X_{Gal}Z Z^{1,5}X_{Gal} ^{0,4}X_{GlcNAc}Z ^{0,4}X_{Gal}Z ^{0,4}X_{GlcNAc}Z ^{0,4}X_{Gal}Z
637.43 3.3
657.36 5.3

Annotations:

Z
665.54 2.1

Annotations:

^{3,5}X_{Gal}Y ^{3,5}X_{Gal}Y ^{3,5}X_{Gal}Y
711.19 2.5

Annotations:

BZ BZ BZ
723.86 3.9
735.02 2.7

Annotations:

Z^{0,4}X_{NeuAc} ^{0,4}X_{NeuAc}Z ^{2,5}A_{GalNAc}Z ^{2,5}A_{GalNAc}Z
744.1 2.1

Annotations:

^{0,2}X_{GlcNAc} ^{0,4}X_{NeuAc}Y Y^{0,4}X_{NeuAc} ^{2,5}A_{GalNAc}Y ^{2,5}A_{GalNAc}Y Z^{1,3}X_{GlcNAc} Z^{1,3}X_{GlcNAc} ^{1,3}X_{GlcNAc}Z ^{1,3}X_{GlcNAc}Z ^{1,3}X_{GlcNAc}Z ^{2,4}X_{NeuAc}Z Z^{2,4}X_{NeuAc} Z^{1,3}X_{GlcNAc}
794.69 3.0

Annotations:

Z Z
795.27 4.5

Annotations:

Z Z
796.4 2.4
804.05 3.3

Annotations:

Y Y
804.51 2.6

Annotations:

^{3,5}X_{GlcNAc} ^{3,5}X_{Gal}Y
816.38 2.3

Annotations:

^{2,5}A_{GalNAc}Z ^{2,5}A_{GalNAc}Z ^{1,3}X_{NeuAc}Z
833.65 3.1

Annotations:

C^{2,5}X_{NeuAc} ^{0,2}A_{GalNAc}Y ^{0,2}A_{GalNAc}Y ^{2,5}A_{Gal}Y ^{2,5}A_{GlcNAc}Y ^{1,3}X_{GalNAc}Z
847.98 5.6

Annotations:

^{3,5}X_{Gal}Y ^{3,5}X_{Gal}Y ^{3,5}X_{Gal}Y Y^{3,5}X_{Gal} Y^{3,5}X_{Gal} Y^{3,5}X_{Gal} ^{3,5}X_{Gal}Y ^{3,5}X_{Gal}Y Y^{2,5}X_{GlcNAc} ^{2,5}X_{Gal}Y Y^{2,5}X_{Gal}
857.17 2.1
861.29 3.1

Annotations:

^{1,5}A_{GalNAc}Y ^{1,5}A_{GalNAc}Y
862.58 2.5

Annotations:

Y^{0,3}X_{GlcNAc} ^{1,4}X_{Gal}Y Y^{1,4}X_{Gal} ^{1,3}X_{NeuAc}Y Y^{1,3}X_{NeuAc}
876.6 4.2

Annotations:

C^{3,5}X_{GlcNAc}
881.97 3.3
883.28 4.4
884.11 11.3
884.5 9.6

Annotations:

Y Y
884.91 6.9

Annotations:

Y Y
885.17 3.5

Annotations:

Y Y
885.49 2.9
886.03 5.6

Annotations:

^{1,5}A_{GlcNAc}Z
886.58 2.2

Annotations:

^{1,5}A_{GlcNAc}Z
907.48 2.5

Annotations:

^{0,3}A_{GlcNAc} ^{1,4}X_{NeuAc}Z
920.45 2.6

Annotations:

^{0,2}X_{Gal} ^{0,4}X_{NeuAc}Y ^{1,5}X_{NeuAc} ^{1,5}X_{NeuAc}
940.55 3.6
940.87 2.8
949.47 2.4
950.06 5.5

Annotations:

CY
950.58 3.1

Annotations:

CY
951.0 5.5

Annotations:

^{2,4}A_{GlcNAc}Y
967.78 2.3
976.45 2.1

Annotations:

B^{1,3}X_{NeuAc} Z^{0,2}X_{Gal} ^{0,2}X_{Gal}Z
977.63 2.8

Annotations:

B^{2,5}X_{NeuAc} ^{2,5}A_{GlcNAc}Z
985.9 2.5
987.75 2.2
991.56 3.2

Annotations:

B^{0,3}X_{NeuAc}
992.03 4.3

Annotations:

^{0,4}A_{GalNAc}Y C^{0,2}X_{Gal} ^{1,5}A_{GlcNAc} ^{1,5}A_{GalNAc}Y Z^{2,5}X_{Gal} ^{2,5}X_{Gal}Z
993.73 3.9

Annotations:

^{0,2}A_{GlcNAc}Z ^{3,5}X_{Gal} ^{3,5}X_{Gal} ^{3,5}X_{Gal} ^{3,5}X_{Gal}
1155.4 5.1

Annotations:

YY
1200.67 7.1

Annotations:

C
1240.59 2.5
1254.61 5.7
1274.8 2.3
1301.55 2.1

Annotations:

^{2,5}X_{Gal}
1318.43 2.1
1321.12 2.6
1377.31 2.2
1390.15 2.2
1398.87 5.3
1399.32 2.9

Annotations:

^{0,3}X_{NeuAc}Z Z^{0,3}X_{NeuAc}
1399.77 7.0

Annotations:

^{0,3}X_{NeuAc}Z Z^{0,3}X_{NeuAc}
1406.01 2.1

Annotations:

Y
1409.7 2.2
1418.59 10.9
1419.98 2.4

Annotations:

^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y Y^{1,3}X_{Gal} Y^{2,4}X_{Gal}
1478.77 18.9
1479.46 11.1

Annotations:

YY
1479.88 15.6

Annotations:

YY
1480.46 4.6
1480.95 9.4
1481.85 2.4
1575.7 2.9
1588.73 2.9
1608.79 5.6

Annotations:

Y Y
1609.7 3.2
1610.02 3.6
1662.91 2.4

Annotations:

Z^{0,3}X_{Gal} ^{0,3}X_{Gal}Z ^{0,3}X_{Gal}Z Z^{0,3}X_{Gal} Z^{0,3}X_{Gal} ^{0,3}X_{Gal}Z ^{0,3}X_{Gal}Z ^{0,3}X_{Gal}Z
1666.53 3.7

Annotations:

^{2,5}X_{Gal} ^{2,5}X_{Gal}
1692.62 2.2

Annotations:

Z^{0,4}X_{Gal} Z^{0,4}X_{GlcNAc} Z^{0,4}X_{Gal} Z^{0,4}X_{GlcNAc} ^{0,4}X_{Gal}Z ^{0,4}X_{Gal}Z ^{0,4}X_{GlcNAc}Z ^{0,4}X_{Gal}Z ^{0,4}X_{GlcNAc}Z ^{0,4}X_{Gal}Z ^{0,4}X_{GlcNAc}Z Z^{0,4}X_{Gal} Z^{0,4}X_{GlcNAc} ^{0,4}X_{Gal}Z
1710.91 2.3

Annotations:

^{0,4}X_{Gal}Y ^{0,4}X_{GlcNAc}Y ^{0,4}X_{Gal}Y Y^{0,4}X_{Gal} Y^{0,4}X_{GlcNAc} Y^{0,4}X_{Gal} Y^{0,4}X_{GlcNAc} ^{0,4}X_{Gal}Y ^{0,4}X_{Gal}Y ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{GlcNAc}Y ^{0,4}X_{Gal}Y ^{0,4}X_{GlcNAc}Y Y^{0,4}X_{Gal} Y^{0,4}X_{GlcNAc}
1726.81 2.6

Annotations:

^{1,3}X_{NeuAc}Y Y^{1,3}X_{NeuAc}
1752.85 3.2

Annotations:

Z Z
1753.18 5.4
1754.54 5.7
1754.81 5.2
1767.01 3.1
1767.83 4.3
1768.77 2.1
1770.0 3.0
1770.96 123.9

Annotations:

Y Y
1771.83 42.4
1772.18 20.1
1773.21 12.1
1773.93 11.5
1774.18 5.6
1840.89 2.4

Annotations:

^{0,2}X_{NeuAc} ^{0,2}X_{NeuAc}
1859.97 2.2

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