Recombinant mucin-type fusion proteins with Galα1,3Gal substitution as Clostridium difficile toxin A inhibitors

PubMed Entry

GlyToucan Accession Number: G08061QE

Peak Intensity
235.18 5.2

Annotations:

^{3,5}A_{GlcNAc}Y ^{3,5}A_{GlcNAc}Y
290.16 63.1

Annotations:

B
291.25 4.0

Annotations:

^{1,4}A_{GalNAc} ^{3,5}X_{Gal}Z B^{2,5}X_{Gal}
364.34 3.2

Annotations:

BY BY CZ CZ BY CZ BY CZ
425.09 4.9

Annotations:

YY
428.44 2.6
439.5 3.4
452.15 3.0

Annotations:

B
470.26 33.4

Annotations:

C
471.3 6.1
503.34 2.7
519.83 25.7

Annotations:

Y
520.63 3.2
526.38 24.0

Annotations:

B
527.34 3.0

Annotations:

Y^{2,4}X_{GlcNAc} ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{2,4}X_{GalNAc}Y
567.28 3.8

Annotations:

BY CZ
569.37 9.2

Annotations:

YZ ZY YZ ZY
587.1 4.1

Annotations:

YY YY
587.38 3.2

Annotations:

YY YY
600.89 5.6

Annotations:

Y^{3,5}X_{Gal} Y^{3,5}X_{Gal} Y^{3,5}X_{Gal} ^{3,5}X_{Gal}Y ^{3,5}X_{Gal}Y ^{3,5}X_{GalNAc}
609.66 3.8

Annotations:

^{0,4}A_{GalNAc}Z ^{1,5}A_{GalNAc}Z B^{0,2}X_{Gal}
610.4 6.9
610.69 3.8
612.6 3.0

Annotations:

Z
621.4 144.3

Annotations:

Y
621.85 86.0
622.24 29.3
623.72 3.4

Annotations:

^{3,5}A_{GalNAc}Z
637.25 10.8

Annotations:

Y
669.3 3.6

Annotations:

^{1,5}A_{GalNAc}Z B^{1,3}X_{Gal} B^{2,4}X_{Gal} ^{0,3}X_{NeuAc}Z
670.08 3.5

Annotations:

Y^{0,2}X_{GlcNAc}
675.3 3.9

Annotations:

Y
688.36 2.8

Annotations:

B
693.91 3.1
702.5 49.6

Annotations:

Y
702.94 12.9

Annotations:

^{1,5}X_{GlcNAc} ^{3,5}X_{NeuAc}Y
703.48 8.8

Annotations:

^{1,5}X_{GlcNAc} ^{3,5}X_{NeuAc}Y
730.4 3.1

Annotations:

^{2,4}X_{GalNAc}Y Y^{2,4}X_{GlcNAc}
736.31 4.3
738.67 3.9

Annotations:

^{0,3}X_{Gal} ^{1,4}X_{Gal} ^{0,3}X_{Gal} ^{0,3}X_{Gal} ^{0,3}X_{Gal}
743.99 3.7
748.31 4.1

Annotations:

^{2,4}A_{GlcNAc}
749.45 24.4

Annotations:

YY
753.41 7.2

Annotations:

^{0,4}X_{Gal} ^{0,4}X_{GlcNAc} ^{0,4}X_{Gal} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{Gal} ^{0,4}X_{GlcNAc}
753.97 7.6

Annotations:

ZZ
754.31 3.7

Annotations:

ZZ
790.44 3.5

Annotations:

YY
860.26 12.9

Annotations:

Z
860.64 8.6

Annotations:

Z
861.34 8.5
878.46 16.4

Annotations:

Y
879.63 2.7
892.24 8.5

Annotations:

^{2,4}X_{Gal}Y ^{2,4}X_{GalNAc}Y Y^{2,4}X_{GlcNAc} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{1,3}X_{Gal}Y
934.57 12.6

Annotations:

YZ ZY YZ ZY
935.18 2.6
935.69 4.1
951.28 3.6

Annotations:

^{0,4}A_{GalNAc}
951.54 4.2

Annotations:

^{0,4}A_{GalNAc}
952.5 40.3

Annotations:

YY YY
952.99 2.7
953.6 7.1
1003.88 2.7

Annotations:

^{0,2}X_{NeuAc}Z
1004.5 7.4

Annotations:

^{0,2}X_{NeuAc}Z
1005.73 3.2
1022.69 6.3

Annotations:

Z
1023.79 2.7
1040.58 89.3

Annotations:

Y
1041.48 23.7
1041.89 7.4
1042.5 7.4
1048.17 2.7

Annotations:

^{1,5}A_{GalNAc}Z
1072.5 3.0
1096.57 56.3

Annotations:

Z
1097.65 19.1
1098.69 6.6
1114.69 15.3

Annotations:

Y
1115.8 8.2
1183.66 4.7

Annotations:

^{0,4}X_{Gal}Y ^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc} ^{0,4}X_{Gal}Y ^{0,4}X_{GlcNAc}Y
1185.7 2.7
1201.61 5.2
1202.77 4.9

Annotations:

Y^{3,5}X_{Gal} Y^{3,5}X_{Gal} Y^{3,5}X_{Gal} ^{3,5}X_{Gal}Y
1207.55 8.8
1208.61 3.0
1216.48 4.5

Annotations:

Y^{0,4}X_{Gal} Y^{0,4}X_{GlcNAc} ^{0,4}X_{Gal}Y ^{1,3}X_{Gal} ^{2,4}X_{Gal} Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} Y^{0,4}X_{Gal} Y^{0,4}X_{GlcNAc}
1225.79 68.4

Annotations:

Z
1226.64 45.3
1227.38 3.9
1227.81 8.4
1243.67 136.0

Annotations:

Y
1244.65 68.6
1245.66 18.0
1246.47 2.7
1274.85 5.6
1276.66 143.4

Annotations:

Y
1277.31 12.5
1277.7 41.7
1278.7 12.3
1278.93 8.0
1387.85 9.6

Annotations:

Z
1388.86 4.0

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