Recombinant mucin-type fusion proteins with Galα1,3Gal substitution as Clostridium difficile toxin A inhibitors

PubMed Entry

GlyToucan Accession Number: G10831FE

Peak Intensity
270.23 4.8

Annotations:

^{0,3}A_{GlcNAc} ^{1,4}X_{NeuAc}Z
272.26 9.5

Annotations:

^{2,5}X_{Gal}Z Z^{2,5}X_{Gal}
288.09 41.8

Annotations:

^{1,4}X_{Gal}Y C^{3,5}X_{NeuAc} Y^{1,4}X_{Gal}
288.35 21.9

Annotations:

^{1,4}X_{Gal}Y Y^{1,4}X_{Gal} C^{3,5}X_{NeuAc}
289.13 5.0
290.16 4978.0

Annotations:

B
291.13 289.2

Annotations:

^{1,4}A_{GalNAc} C^{0,3}X_{Gal} ^{1,4}A_{GlcNAc} ^{3,5}X_{Gal}Z
370.1 21.9

Annotations:

^{0,4}X_{NeuAc}Z Z^{0,4}X_{NeuAc} ^{2,5}A_{GalNAc}Z ^{2,5}A_{GalNAc}Z
371.2 5.8
442.37 11.6
449.22 6.7

Annotations:

^{0,2}X_{NeuAc}Y Y^{0,2}X_{NeuAc} Z^{0,2}X_{GlcNAc} ^{0,2}X_{Gal}Z Z^{0,2}X_{Gal}
452.31 4.3

Annotations:

B B
468.34 7.0

Annotations:

C^{2,5}X_{NeuAc} ^{0,2}A_{GalNAc}Y ^{0,2}A_{GalNAc}Y ^{1,3}X_{GalNAc}Z
470.29 4.3

Annotations:

C C
474.33 4.9

Annotations:

^{0,3}X_{Gal}Y ^{1,4}X_{Gal} Y^{0,3}X_{Gal} ^{0,3}X_{Gal}Y ^{1,4}X_{Gal} ^{0,3}X_{Gal}Y
476.33 5.5
478.8 11.8

Annotations:

Y Y
479.19 7.6

Annotations:

^{1,4}X_{Gal}Z Z^{1,4}X_{Gal} Z^{0,3}X_{GlcNAc}
505.86 4.6

Annotations:

^{0,3}X_{Gal}Z Z^{0,3}X_{Gal} ^{0,3}X_{Gal}Z ^{0,3}X_{Gal}Z
529.84 9.0

Annotations:

^{2,4}X_{Gal} Y^{0,4}X_{Gal} ^{0,4}X_{Gal}Y ^{0,4}X_{Gal}Y ^{1,3}X_{Gal} ^{2,4}X_{Gal} B^{2,5}X_{NeuAc} ^{0,4}X_{Gal}Y ^{1,3}X_{Gal}
537.31 8.4

Annotations:

^{0,4}X_{NeuAc}Z ^{1,3}X_{NeuAc}Y Y^{1,3}X_{NeuAc}
537.69 5.7

Annotations:

^{0,4}X_{NeuAc}Z ^{1,3}X_{NeuAc}Y Y^{1,3}X_{NeuAc} ^{2,5}A_{GalNAc}Z
538.32 14.7

Annotations:

^{2,5}A_{GalNAc}Z
544.05 4.4

Annotations:

B^{0,3}X_{NeuAc}
548.38 9.6

Annotations:

C^{2,5}X_{NeuAc} ^{1,3}X_{GalNAc}Z
549.65 12.0
549.85 12.9
550.23 24.5

Annotations:

Z Z
550.84 37.1

Annotations:

Z Z
558.82 351.4

Annotations:

^{1,4}X_{Gal}Z Z^{1,4}X_{Gal}
559.82 10535.3

Annotations:

Y Y
560.32 1828.4

Annotations:

B^{3,5}X_{NeuAc} ^{1,4}X_{NeuAc}Y
560.81 89.4
561.22 11.0
564.84 4.6

Annotations:

B^{0,3}X_{Gal}
572.88 5.7
575.15 12.3
581.21 36.0

Annotations:

B^{3,5}X_{Gal}
581.45 28.7

Annotations:

B^{3,5}X_{Gal}
624.38 5.8
625.4 4.6
626.07 6.5
647.26 5.3

Annotations:

^{1,4}X_{NeuAc} ^{1,4}X_{NeuAc}
649.39 14.2

Annotations:

YZ ZY YZ ZY
650.6 6.0
653.41 5.3

Annotations:

^{0,2}A_{GalNAc}
658.31 7.5
660.22 21.5

Annotations:

^{0,3}X_{Gal} ^{0,3}X_{Gal}
664.5 8.7
665.41 78.7
665.84 27.9
666.95 5.0

Annotations:

YY YY
667.33 18.1

Annotations:

YY YY
668.14 7.8

Annotations:

^{3,5}X_{Gal} ^{3,5}X_{Gal}
674.34 24.4
674.74 11.5

Annotations:

B^{0,4}X_{Gal} ^{0,4}X_{Gal} ^{0,4}X_{Gal}
675.39 27.1

Annotations:

Y
809.38 14.6

Annotations:

^{3,5}A_{GalNAc}
810.13 12.5
810.42 10.7
811.38 13.2

Annotations:

YZ ZY
812.26 4.6

Annotations:

^{1,5}A_{GalNAc}Z ^{1,5}A_{GalNAc}Z
827.39 114.8

Annotations:

^{1,4}X_{GlcNAc} ^{1,4}X_{GalNAc}
828.35 38.3
829.41 4499.0

Annotations:

YY
830.4 819.1

Annotations:

^{1,5}A_{GalNAc}Y ^{1,5}A_{GalNAc}Y
831.36 58.6

Annotations:

^{0,3}X_{NeuAc}Z Z^{0,3}X_{NeuAc}
832.63 4.4
864.65 5.1
896.13 4.3

Annotations:

^{1,3}X_{NeuAc}Z Z^{1,3}X_{NeuAc}
896.4 7.5

Annotations:

^{1,3}X_{NeuAc}Z Z^{1,3}X_{NeuAc}
914.45 6.6

Annotations:

^{1,3}X_{NeuAc}Y Y^{1,3}X_{NeuAc}
967.27 4.4
1040.66 66.8

Annotations:

Y Y
1041.36 16.9
1041.59 9.0
1042.48 10.4

Annotations:

^{0,4}X_{Gal}Z Z^{0,4}X_{Gal} ^{0,4}X_{Gal}Z ^{0,4}X_{Gal}Z
1058.59 4.5

Annotations:

^{1,3}X_{NeuAc}Z Z^{1,3}X_{NeuAc}
1060.41 6.4

Annotations:

^{0,4}X_{Gal}Y ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{Gal}Y ^{1,3}X_{Gal} ^{2,4}X_{Gal} Y^{0,4}X_{Gal} ^{0,4}X_{Gal}Y
1074.35 5.8
1074.67 7.4
1075.47 4.9
1076.71 143.7

Annotations:

^{1,3}X_{NeuAc}Y Y^{1,3}X_{NeuAc}
1077.56 78.1
1078.56 5.2
1100.42 39.0
1101.52 21.6
1102.48 93.2

Annotations:

Z Z
1102.99 7.0
1103.77 6.5
1116.57 6.2
1116.9 5.2
1118.41 572.1
1120.42 13747.9

Annotations:

Y Y
1121.47 2717.2
1122.6 54.4
1122.92 7.0
1123.73 5.0
1142.84 4.5
1303.85 5.8

There are 2 similar spectra:

Id Structure Score

2650

0.94

125

0.80
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