Recombinant mucin-type fusion proteins with Galα1,3Gal substitution as Clostridium difficile toxin A inhibitors

PubMed Entry

GlyToucan Accession Number: G58386YP

Peak Intensity
170.1 45.9

Annotations:

C
179.02 115.3

Annotations:

C
202.04 63.8

Annotations:

BY CZ
204.01 32.6

Annotations:

YZ ZY
220.19 46.3

Annotations:

CY
235.12 558.5

Annotations:

^{3,5}A_{GlcNAc}Y
247.13 590.9

Annotations:

^{2,5}A_{GlcNAc}Z B^{2,5}X_{NeuAc} Z^{3,5}X_{GlcNAc}
248.04 36.5

Annotations:

C^{1,5}X_{Gal} Y^{0,3}X_{GlcNAc} ^{1,4}X_{Gal}Y Y^{1,4}X_{Gal}
262.19 41.5

Annotations:

B
272.16 56.4
275.11 55.3

Annotations:

ZZ ZZ
290.14 4855.0

Annotations:

B
291.14 400.4

Annotations:

^{1,4}A_{GalNAc} ^{3,5}X_{Gal}Z
308.16 477.9

Annotations:

C
311.26 66.3
365.3 35.1

Annotations:

Z
383.18 66.7

Annotations:

^{2,4}A_{GlcNAc}
384.25 37.8

Annotations:

YY
389.36 98.9

Annotations:

ZZ
401.31 38.0

Annotations:

^{1,5}X_{NeuAc}Z Z^{0,3}X_{Gal} Z^{1,4}X_{Gal} Z^{0,3}X_{Gal} ^{0,3}X_{Gal}Z ^{3,5}X_{GlcNAc} ^{3,5}X_{Gal}Y
407.25 1189.6

Annotations:

YZ ZY
408.25 144.4

Annotations:

B^{1,3}X_{NeuAc} ^{2,5}X_{NeuAc}Z ^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc} ^{0,4}X_{Gal}Y
408.84 60.7

Annotations:

^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc} ^{0,4}X_{Gal}Y ^{0,2}X_{NeuAc}Y Z^{3,5}X_{Gal} Z^{3,5}X_{Gal} ^{3,5}X_{Gal}Z
417.76 36.4

Annotations:

Y^{3,5}X_{Gal} Y^{3,5}X_{Gal} ^{3,5}X_{Gal}Y
425.25 291.7

Annotations:

YY
438.79 3716.5

Annotations:

Y
439.3 1248.4
439.8 66.4

Annotations:

C^{2,5}X_{Gal}
452.29 41.1

Annotations:

B
470.27 4422.3

Annotations:

C
471.25 764.9
486.81 229.1

Annotations:

^{1,5}A_{GalNAc}Z
487.41 85.1
489.76 67.4

Annotations:

^{0,4}X_{Gal}Y ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{GlcNAc}Y ^{0,4}X_{Gal}Y ^{0,2}X_{NeuAc}
490.07 47.4

Annotations:

^{0,4}X_{Gal}Y ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{GlcNAc}Y ^{0,4}X_{Gal}Y ^{0,2}X_{NeuAc}
498.94 72.4
499.33 49.3
503.31 35.8
519.83 2953.0

Annotations:

Y
520.29 1347.8
520.91 53.6
526.29 175.5

Annotations:

B
527.29 64.4

Annotations:

Y^{2,4}X_{GlcNAc} ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{2,4}X_{GalNAc}Y
540.82 70.2

Annotations:

^{0,2}X_{Gal} ^{0,4}X_{NeuAc} ^{2,5}A_{GalNAc}
554.84 731.3

Annotations:

^{0,4}X_{NeuAc}Y
555.35 218.1

Annotations:

^{0,4}X_{NeuAc}Y ^{0,3}X_{Gal} ^{1,4}X_{Gal} ^{0,3}X_{Gal} ^{0,3}X_{Gal}
555.9 34.3

Annotations:

^{0,3}X_{Gal} ^{1,4}X_{Gal} ^{0,3}X_{Gal} ^{0,3}X_{Gal} ^{2,5}A_{GalNAc}Y ^{2,4}X_{NeuAc}Z
561.79 46.8
562.39 33.1
565.33 32.1
567.12 34.0

Annotations:

^{0,3}X_{Gal}Z
567.44 58.4

Annotations:

^{0,3}X_{Gal}Z
567.87 32.3
568.34 63.8
569.33 395.2

Annotations:

YZ ZY YZ ZY
570.87 377.7

Annotations:

^{1,3}X_{Gal} ^{0,4}X_{Gal} ^{0,4}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{Gal} ^{0,4}X_{GlcNAc}
571.38 178.6
657.38 602.7

Annotations:

Z
658.47 60.9
671.43 66.5

Annotations:

Z^{1,3}X_{Gal} Z^{2,4}X_{Gal} ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{0,4}X_{Gal} Z^{1,3}X_{Gal} Z^{2,4}X_{Gal} Z^{0,4}X_{Gal} Z^{0,4}X_{GlcNAc}
675.37 754.7

Annotations:

Y
676.4 139.6
683.34 160.2

Annotations:

^{1,5}A_{GalNAc}Z
689.34 155.7

Annotations:

^{2,4}X_{GalNAc} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} Y^{0,4}X_{Gal} Y^{0,4}X_{GlcNAc}
690.39 38.2
713.36 142.3

Annotations:

ZZ
731.42 2727.1

Annotations:

Z
732.42 659.5
733.44 48.6
749.41 700.0

Annotations:

Y
750.67 71.7
818.44 216.4

Annotations:

^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc} ^{0,4}X_{Gal}Y
819.46 126.2

Annotations:

^{0,2}X_{NeuAc}Y Z^{3,5}X_{Gal} Z^{3,5}X_{Gal} ^{3,5}X_{Gal}Z
834.48 84.8

Annotations:

^{1,3}X_{NeuAc}Y
836.45 83.4
837.62 31.5

Annotations:

Y^{3,5}X_{Gal} Y^{3,5}X_{Gal} ^{3,5}X_{Gal}Y
842.48 198.8
843.61 46.9
851.69 37.7

Annotations:

^{0,4}X_{Gal}Y ^{1,3}X_{Gal} ^{2,4}X_{Gal} Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} Y^{0,4}X_{Gal} Y^{0,4}X_{GlcNAc}
852.44 32.1
860.46 2992.6

Annotations:

Z
861.46 1011.0
862.59 35.4
878.49 12770.7

Annotations:

Y
879.46 4311.5
880.57 102.0
893.66 67.8

Annotations:

Z
894.64 42.5
911.48 3894.5

Annotations:

Y
912.51 1390.9
980.72 50.8

Annotations:

^{0,4}X_{Gal}Y ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{GlcNAc}Y ^{0,4}X_{Gal}Y
981.48 50.6

Annotations:

^{0,2}X_{NeuAc}
1004.52 230.7
1005.63 61.0
1022.52 1773.8

Annotations:

Z
1023.51 831.7
1040.53 2233.3

Annotations:

Y
1041.58 873.7
1080.65 32.4
1082.48 43.8

Annotations:

^{0,2}X_{Gal} ^{0,4}X_{NeuAc}

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