Recombinant mucin-type fusion proteins with Galα1,3Gal substitution as Clostridium difficile toxin A inhibitors

PubMed Entry

GlyToucan Accession Number: G30524IG

Peak Intensity
222.24 9.4

Annotations:

Y
223.1 1.9
235.11 2.0

Annotations:

^{3,5}A_{GlcNAc}Y
236.08 2.1
236.39 2.9
247.13 3.1

Annotations:

^{2,5}A_{GlcNAc}Z
265.03 1.9

Annotations:

^{2,5}A_{Gal} ^{2,5}A_{GlcNAc}Y
272.36 1.7
275.2 2.0
276.11 3.9

Annotations:

^{3,5}A_{GalNAc}Y
298.18 3.5
304.7 1.5
305.29 1.7
323.35 3.5

Annotations:

B
335.19 1.7
339.85 2.5
340.86 1.5

Annotations:

C
347.19 5.2
348.09 3.6
348.41 2.0
364.13 6.1

Annotations:

BY CZ
365.27 76.4
366.28 11.9
382.8 1.9

Annotations:

^{2,4}A_{GlcNAc}
383.21 39.8

Annotations:

^{2,4}A_{GlcNAc}
383.56 1.9

Annotations:

^{2,4}A_{GlcNAc}
384.34 6.1
387.45 1.5
389.45 7.6
395.09 1.5
397.28 4.0

Annotations:

^{3,5}A_{GlcNAc}
403.09 2.1
407.37 78.7

Annotations:

Z
408.13 16.8
408.62 2.7
425.28 213.7

Annotations:

Y
426.12 22.0
426.51 16.7
428.42 2.0
429.2 1.9
444.29 1.9
461.19 6.5
461.48 6.2
462.29 3.9
466.22 2.4

Annotations:

^{0,2}A_{GalNAc}Z
473.21 2.4
479.53 5.0
485.11 3.5
485.49 1.8
503.47 1.9
509.25 1.6
515.22 1.6
521.11 13.9

Annotations:

^{1,5}A_{GalNAc}Z
521.39 16.8

Annotations:

^{1,5}A_{GalNAc}Z
522.4 3.2
522.69 2.5
526.24 63.5

Annotations:

B
527.35 28.4
527.93 2.1
531.13 1.8
533.69 4.2
545.28 15.4
546.2 2.8
569.38 28.2

Annotations:

Z
569.65 8.2

Annotations:

Z
570.47 9.3
573.35 1.7
574.62 1.5
586.12 4.5

Annotations:

^{0,4}A_{GalNAc}
586.48 8.6

Annotations:

^{0,4}A_{GalNAc}
587.08 19.2

Annotations:

Y
587.59 11.2

Annotations:

Y
587.85 2.3
588.3 18.0
589.32 6.1
591.43 4.8
592.27 3.1
600.42 11.5

Annotations:

^{3,5}A_{GalNAc}
629.36 41.9
630.33 6.9

Annotations:

^{2,5}A_{GalNAc}
631.29 1.8
635.99 2.8
641.56 2.0
645.8 2.0

Annotations:

^{0,2}A_{GalNAc}
647.47 46.2
648.22 7.0
648.46 11.0
655.26 3.6
659.31 1.7
665.52 5.7
671.46 10.0
671.95 3.1
672.54 2.8
681.58 1.7
689.39 763.2
690.4 196.8
707.42 357.2
708.47 90.4
712.5 1.9
720.06 1.9

There are 3 similar spectra:

Id Structure Score

2477

0.69

2494

0.69

2226

0.57
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