Recombinant mucin-type fusion proteins with Galα1,3Gal substitution as Clostridium difficile toxin A inhibitors

PubMed Entry

GlyToucan Accession Number: G31601FB

Peak Intensity
168.05 1.9
171.98 1.4
172.15 0.8
173.98 1.9
179.15 4.2

Annotations:

C
181.94 2.3
182.21 1.3
186.06 40.5

Annotations:

ZZ
187.86 0.8
190.29 1.1
192.13 7.1
200.21 2.4
202.13 131.4

Annotations:

B
203.08 3.6
204.13 220.4

Annotations:

YZ ZY
205.13 5.5
210.18 0.7
215.91 0.7
220.03 75.0

Annotations:

C
221.11 1.4

Annotations:

^{2,4}A_{GalNAc}
222.23 1.7

Annotations:

YY
227.07 2.7
227.34 1.2
233.95 6.8
234.25 0.9
240.23 0.8
243.28 1.5
245.15 1.4
246.05 3.5
246.31 3.3
252.48 1.3
257.15 3.3
262.16 43.6

Annotations:

^{0,4}A_{GalNAc} ^{1,3}A_{GalNAc}
263.12 1.6

Annotations:

^{0,2}A_{GalNAc}Z
264.16 7.6
264.41 4.0
276.19 28.4

Annotations:

^{3,5}A_{GalNAc}
282.21 1.6
288.14 3.4

Annotations:

^{2,5}A_{GalNAc}Z
291.82 0.8

Annotations:

^{0,3}A_{GalNAc} ^{1,4}A_{GalNAc}
292.93 0.7
293.3 1.4
293.98 0.8
299.17 6.4
299.42 3.8
300.07 0.8
305.2 1.4
311.34 2.6
312.18 35.4
313.05 1.0
317.23 1.5
324.14 3.2
324.44 1.6
329.15 8.4
329.99 0.9
335.49 0.8
336.45 0.8

Annotations:

^{1,5}A_{GalNAc}Y
347.28 108.5
348.2 5.4
359.37 16.0

Annotations:

^{1,5}A_{GalNAc}Z
360.36 0.9
365.26 87.9
366.25 65.8

Annotations:

Z
367.33 2.0
371.15 16.4
379.03 1.7
379.3 2.4
384.27 20.5

Annotations:

Y
386.23 2.4
389.25 65.9
390.02 3.9
406.19 0.8
407.27 6842.6

Annotations:

Z
408.26 286.8
409.31 1.0
425.28 216.8

Annotations:

Y
426.18 9.6
426.44 6.7
427.26 2.4
427.49 0.9
445.16 1.1
446.9 2.3
467.12 1.7
467.37 1.5
482.92 1.1
485.34 1.5
502.24 0.8
526.23 1.5
527.31 192.3
528.32 11.5
542.35 0.8
542.99 1.1
545.44 18.5
546.57 3.0
550.79 0.8
551.04 0.7
555.18 1.3
555.74 1.1
559.92 0.9
560.68 1.0

There are 13 similar spectra:

Id Structure Score

3034

1.00

327

1.00

3649

1.00

177

1.00

450

0.99

94

0.99

178

0.95

2673

0.90

3650

0.85

3037

0.73

246

0.70

3035

0.67

558

0.51
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