In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.

PubMed Entry

GlyToucan Accession Number: G87313QP

Peak Intensity
450.2 289.0

Annotations:

^{1,3}A_{Man}Z B^{1,3}X_{Gal} B^{0,4}X_{Gal} B^{0,2}X_{Gal}
470.0 175.0

Annotations:

C
527.8 245.0

Annotations:

CY CY CY CY YY
688.2 156.0

Annotations:

BY CZ
775.3 237.0

Annotations:

C^{0,4}X_{Fuc} C^{1,3}X_{NeuAc}
822.3 189.0

Annotations:

^{1,5}A_{Man}Y
835.8 421.0

Annotations:

^{1,3}X_{Man}Y Y^{1,3}X_{Man}
856.9 414.0
857.4 251.0
895.8 195.0

Annotations:

YY YY
905.0 183.0

Annotations:

B^{3,5}X_{Fuc} C^{1,5}X_{Gal} ^{1,5}A_{GlcNAc}Y Z^{0,2}X_{Fuc} ^{0,2}X_{Fuc}Z Z^{1,5}X_{Man} ^{1,5}X_{Man}Z Z^{1,5}X_{GlcNAc} Z^{2,5}X_{Gal}
905.4 340.0

Annotations:

C^{1,5}X_{Gal} ^{1,5}A_{GlcNAc}Y Z^{0,2}X_{Fuc} ^{0,2}X_{Fuc}Z Z^{1,5}X_{Man} ^{1,5}X_{Man}Z Z^{1,5}X_{GlcNAc} Z^{2,5}X_{Gal} ^{0,2}A_{GlcNAc}Z B^{0,4}X_{Gal} ^{0,2}A_{Man}Z B^{3,5}X_{Fuc}
910.7 201.0

Annotations:

BZ
920.4 414.0

Annotations:

^{1,4}A_{GlcNAc}Y Z^{0,3}X_{Fuc} Z^{3,5}X_{Gal} ^{0,3}X_{Fuc}Z
938.1 261.0
958.3 265.0

Annotations:

YY YY
975.5 104.0

Annotations:

^{1,5}A_{Man}Z
980.5 271.0

Annotations:

C^{1,5}X_{NeuAc} ^{0,3}A_{GlcNAc}Y
1009.0 432.0

Annotations:

CY CY
1022.3 160.0

Annotations:

YZ ZY ZY ZY YZ YZ
1029.8 501.0

Annotations:

B^{2,5}X_{Gal} B^{0,2}X_{Fuc} B^{0,2}X_{Fuc} ^{2,4}A_{GlcNAc}Z ^{2,4}A_{GlcNAc}Z Y^{2,4}X_{GlcNAc}
1030.8 289.0

Annotations:

YZ ZY YY YY YY
1032.4 162.0

Annotations:

C^{1,4}X_{NeuAc}
1039.0 153.0

Annotations:

CY CY YY YZ ZY
1073.0 136.0

Annotations:

Z^{1,5}X_{Gal} Z^{1,5}X_{Fuc} ^{1,5}X_{Fuc}Z ^{1,5}X_{Fuc}Z B^{1,5}X_{NeuAc} ^{2,5}X_{NeuAc}Z ^{1,3}X_{Man}Z Z^{0,4}X_{Fuc} ^{0,4}X_{Fuc}Z Z^{1,3}X_{Man} ^{0,4}X_{Fuc}Z Z^{1,3}X_{Man} ^{1,3}X_{NeuAc}Z ^{1,5}X_{Gal}Z Z^{1,5}X_{Gal}
1082.0 110.0

Annotations:

Y^{1,5}X_{Fuc} ^{1,3}X_{Man}Y Y^{0,4}X_{Fuc} ^{0,4}X_{Fuc}Y Y^{1,3}X_{Man} ^{0,4}X_{Fuc}Y Y^{1,3}X_{Man} ^{1,3}X_{NeuAc}Y ^{1,5}X_{Gal}Y Y^{1,5}X_{Gal} Y^{1,5}X_{Gal} ^{1,5}X_{Fuc}Y ^{1,5}X_{Fuc}Y C^{1,5}X_{NeuAc} ^{2,5}X_{NeuAc}Y
1082.2 305.0

Annotations:

^{0,4}X_{Fuc}Y Y^{1,5}X_{Fuc} ^{1,3}X_{Man}Y Y^{0,4}X_{Fuc} ^{0,4}X_{Fuc}Y Y^{1,3}X_{Man} Y^{1,3}X_{Man} ^{1,3}X_{NeuAc}Y ^{1,5}X_{Gal}Y Y^{1,5}X_{Gal} Y^{1,5}X_{Gal} ^{1,5}X_{Fuc}Y ^{1,5}X_{Fuc}Y C^{1,5}X_{NeuAc} ^{2,5}X_{NeuAc}Y
1085.8 177.0

Annotations:

Y^{1,5}X_{GlcNAc}
1090.9 329.0

Annotations:

B^{0,2}X_{NeuAc}
1091.3 416.0

Annotations:

B^{0,2}X_{NeuAc}
1092.2 242.0
1093.0 249.0

Annotations:

BZ
1093.5 373.0

Annotations:

ZZ ZZ ZZ
1111.5 450.0

Annotations:

YY YY YY
1111.9 3053.0

Annotations:

YY YY YY
1112.4 1972.0

Annotations:

YY YY YY
1113.0 1358.0
1113.4 822.0
1113.8 219.0
1114.0 183.0

Annotations:

YY
1114.3 128.0

Annotations:

YY
1129.9 211.0

Annotations:

Y^{1,4}X_{GlcNAc}
1133.0 225.0

Annotations:

C^{1,5}X_{Fuc} C^{1,5}X_{Fuc} Y^{0,2}X_{Fuc} ^{0,2}X_{Fuc}Y ^{0,2}X_{Fuc}Y ^{2,5}A_{GlcNAc}
1133.5 377.0

Annotations:

^{2,5}A_{GlcNAc}
1134.3 327.0

Annotations:

C^{1,4}X_{NeuAc} ^{2,4}X_{NeuAc}Y
1141.9 273.0

Annotations:

^{2,5}A_{Man}Y C^{0,4}X_{Gal}
1156.4 126.0

Annotations:

Y^{3,5}X_{Fuc} ^{3,5}X_{Fuc}Y ^{3,5}X_{Fuc}Y Y^{0,2}X_{Fuc} Y^{2,5}X_{GlcNAc} Y^{2,5}X_{Gal}
1165.5 248.0

Annotations:

BZ
1166.9 379.0

Annotations:

CZ CZ BY BY
1167.5 146.0

Annotations:

^{3,5}X_{GlcNAc}Z Z^{3,5}X_{GlcNAc} ^{1,4}X_{Fuc}Z Z^{0,3}X_{Gal} Z^{1,4}X_{Gal} ^{1,4}X_{Fuc}Z Z^{3,5}X_{GlcNAc} ^{1,5}X_{NeuAc}Z Z^{1,4}X_{Fuc}
1174.5 180.0

Annotations:

^{2,4}X_{GlcNAc}Z Z^{2,4}X_{GlcNAc} Z^{2,4}X_{GlcNAc} ^{0,2}X_{NeuAc}Z Z^{0,2}X_{NeuAc} Z^{0,2}X_{NeuAc} ^{2,5}X_{NeuAc}Z
1174.8 165.0

Annotations:

^{2,4}X_{GlcNAc}Z Z^{2,4}X_{GlcNAc} Z^{2,4}X_{GlcNAc} ^{0,2}X_{NeuAc}Z Z^{0,2}X_{NeuAc} Z^{0,2}X_{NeuAc} ^{2,5}X_{NeuAc}Z
1177.0 142.0

Annotations:

^{1,5}X_{NeuAc}Y Y^{1,4}X_{Fuc} Y^{0,3}X_{Gal} Y^{1,4}X_{Gal} ^{1,4}X_{Fuc}Y ^{1,4}X_{Fuc}Y ^{0,3}X_{Gal}
1180.6 483.0
1180.9 117.0
1181.5 250.0

Annotations:

BZ
1182.5 126.0

Annotations:

B
1182.9 388.0

Annotations:

B
1183.9 169.0

Annotations:

BY CZ
1184.1 234.0

Annotations:

CY CY
1184.5 244.0

Annotations:

Y
1186.4 543.0

Annotations:

Y^{3,5}X_{GlcNAc} ^{1,4}X_{Man}Y Y^{0,3}X_{Fuc} Y^{3,5}X_{Gal}
1196.5 676.0
1202.4 117.0

Annotations:

Y^{3,5}X_{Fuc}
1205.5 623.0
1207.0 165.0

Annotations:

^{3,5}X_{NeuAc}Y Y^{3,5}X_{NeuAc} Y^{3,5}X_{NeuAc}
1255.5 197.0

Annotations:

B^{1,5}X_{NeuAc} ^{3,5}A_{GlcNAc}Z ^{1,4}A_{Man}Z ^{0,4}X_{Gal}Z ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{0,4}X_{Fuc} ^{0,4}X_{Fuc}Z ^{1,3}X_{Fuc}Z ^{2,4}X_{Fuc}Z Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} Z^{0,4}X_{Gal} Z^{1,3}X_{Gal} Z^{2,4}X_{Gal} ^{0,4}X_{Fuc}Z ^{1,3}X_{Fuc}Z Z^{1,3}X_{Fuc} ^{2,4}X_{Fuc}Z Z^{2,4}X_{Fuc} Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} Z^{0,4}X_{Gal} Z^{1,3}X_{Gal} Z^{2,4}X_{Gal} ^{1,3}X_{Fuc}Z ^{2,4}X_{Fuc}Z ^{1,3}X_{NeuAc}Z
1262.5 173.0
1264.5 157.0

Annotations:

^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y ^{1,3}X_{Fuc}Y ^{2,4}X_{Fuc}Y Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{1,3}X_{Fuc}Y ^{2,4}X_{Fuc}Y Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{2,5}X_{NeuAc} Y^{0,4}X_{Fuc} ^{0,4}X_{Fuc}Y ^{0,4}X_{Fuc}Y Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{1,3}X_{Fuc}Y ^{2,4}X_{Fuc}Y ^{1,3}X_{NeuAc}Y ^{0,4}X_{Gal}Y
1265.7 106.0

Annotations:

^{3,5}X_{Fuc}Y Y^{3,5}X_{Fuc} ^{3,5}X_{Fuc}Y Y^{3,5}X_{Fuc} ^{3,5}X_{Fuc}Y Y^{3,5}X_{Fuc}
1272.0 179.0

Annotations:

C^{3,5}X_{Fuc} C^{3,5}X_{Fuc} ^{0,3}X_{NeuAc} Y^{0,4}X_{Fuc} Y^{0,4}X_{Fuc} Y^{0,4}X_{Fuc} ^{0,4}X_{Fuc}Y Y^{1,3}X_{NeuAc} Y^{1,3}X_{NeuAc} ^{0,4}X_{Fuc}Y ^{0,4}X_{Fuc}Y ^{1,3}X_{NeuAc}Y ^{1,5}X_{Gal}Y Y^{1,5}X_{Man}
1277.7 241.0

Annotations:

Z
1285.4 757.0

Annotations:

Z Z Z
1286.0 1163.0

Annotations:

Y
1286.5 997.0

Annotations:

Y
1287.0 1758.0

Annotations:

C^{2,5}X_{NeuAc}
1287.5 870.0

Annotations:

C^{2,5}X_{NeuAc}
1288.5 245.0

Annotations:

Y^{1,5}X_{Gal} ^{1,5}X_{Man}
1294.6 222.0

Annotations:

Y Y Y
1294.9 307.0

Annotations:

Y Y Y
1295.3 213.0
1295.5 338.0
1296.0 289.0
1296.3 217.0
1302.7 515.0

Annotations:

Y^{0,2}X_{Gal}
1307.5 128.0

Annotations:

^{0,2}X_{Gal} ^{0,4}X_{NeuAc}
1324.7 131.0
1334.5 133.0

Annotations:

Y^{2,5}X_{Fuc}
1337.6 349.0

Annotations:

^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{1,3}X_{Fuc} ^{2,4}X_{Fuc}
1337.9 784.0

Annotations:

^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{1,3}X_{Fuc} ^{2,4}X_{Fuc}
1338.3 307.0

Annotations:

^{3,5}X_{Fuc} ^{3,5}X_{Fuc} ^{3,5}X_{Fuc}
1338.6 149.0

Annotations:

^{3,5}X_{Fuc} ^{3,5}X_{Fuc} ^{3,5}X_{Fuc}
1346.2 188.0

Annotations:

CY CY
1346.6 1258.0

Annotations:

CY CY
1347.0 133.0

Annotations:

^{1,3}X_{Gal}Y Y^{1,3}X_{Man}
1347.5 364.0
1348.5 404.0

Annotations:

Y^{0,3}X_{Fuc} Y^{3,5}X_{Gal}
1348.8 129.0

Annotations:

Y^{0,3}X_{Fuc} Y^{3,5}X_{Gal}
1357.5 476.0
1358.0 393.0
1359.8 221.0

Annotations:

B^{1,4}X_{NeuAc}
1363.7 173.0
1364.6 133.0

Annotations:

Y^{3,5}X_{Fuc}
1366.4 112.0
1366.7 252.0
1367.1 737.0
1367.6 105.0
1368.3 134.0
1552.7 109.0
1654.6 123.0

Annotations:

CY
1713.7 215.0

Annotations:

Y^{3,5}X_{Fuc} ^{3,5}X_{Fuc}Y
1759.0 193.0
1888.0 170.0
2023.8 132.0
2046.8 123.0

Annotations:

Y^{3,5}X_{GlcNAc}
2064.9 458.0
2163.8 254.0

Annotations:

B
2181.7 146.0

Annotations:

C
2183.0 777.0
2184.1 149.0

There are 1 similar spectra:

Id Structure Score

2579

1.00
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