In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.

PubMed Entry

GlyToucan Accession Number: G78120NM

Peak Intensity
470.2 183.0

Annotations:

C
628.2 145.0

Annotations:

^{0,2}A_{GlcNAc}Z
675.3 105.0
919.3 147.0

Annotations:

^{0,2}X_{NeuAc}Z B^{3,5}X_{GlcNAc} B^{3,5}X_{GlcNAc} Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} B^{2,4}X_{NeuAc} Z^{0,2}X_{NeuAc}
966.0 166.0

Annotations:

YY YY
979.0 135.0

Annotations:

BY CZ
1004.3 108.0
1010.9 234.0
1038.5 138.0

Annotations:

C Y Y
1071.9 172.0

Annotations:

B^{0,2}X_{NeuAc} B^{0,2}X_{NeuAc} Z^{1,5}X_{Fuc} Z^{1,5}X_{Fuc}
1082.5 177.0

Annotations:

^{1,4}X_{NeuAc}Y Y^{1,4}X_{NeuAc}
1089.9 212.0

Annotations:

C
1103.3 417.0

Annotations:

Z^{1,5}X_{NeuAc} ^{1,5}X_{NeuAc}Z Y^{0,3}X_{Fuc} ^{3,5}X_{GlcNAc} Y^{0,3}X_{Fuc} ^{3,5}X_{GlcNAc}
1103.9 264.0

Annotations:

C^{3,5}X_{NeuAc} C^{3,5}X_{NeuAc}
1110.8 162.0

Annotations:

^{1,4}A_{Man} ^{1,4}A_{GlcNAc}Y ^{2,4}X_{GlcNAc} ^{2,4}X_{GlcNAc} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{2,4}A_{GlcNAc} ^{0,2}X_{NeuAc}Y Y^{0,2}X_{NeuAc}
1111.4 112.0

Annotations:

Y^{3,5}X_{Fuc} Y^{3,5}X_{Fuc} ^{1,4}X_{GlcNAc}Z Z^{1,4}X_{GlcNAc} ^{1,5}X_{NeuAc}Y Y^{1,5}X_{NeuAc}
1123.0 171.0

Annotations:

BZ
1140.4 262.0

Annotations:

Y Y
1147.4 305.0
1175.3 265.0

Annotations:

^{1,5}X_{NeuAc}Z ^{1,5}X_{NeuAc}Z Z^{0,3}X_{Fuc} Z^{0,3}X_{Fuc}
1182.5 135.0

Annotations:

B B
1183.5 259.0

Annotations:

^{2,4}A_{GlcNAc}Z ^{0,2}X_{NeuAc}Y Z^{3,5}X_{Fuc} ^{0,2}X_{NeuAc}Y Z^{3,5}X_{Fuc}
1183.9 156.0

Annotations:

^{0,2}X_{NeuAc}Y Z^{3,5}X_{Fuc} ^{0,2}X_{NeuAc}Y Z^{3,5}X_{Fuc}
1184.4 288.0

Annotations:

^{1,5}X_{NeuAc}Y ^{1,5}X_{NeuAc}Y Y^{0,3}X_{Fuc} Y^{0,3}X_{Fuc}
1184.9 138.0

Annotations:

^{1,5}X_{NeuAc}Y ^{1,5}X_{NeuAc}Y Y^{0,3}X_{Fuc} Y^{0,3}X_{Fuc}
1190.0 159.0

Annotations:

Z^{0,4}X_{Fuc} Z^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Z Z^{1,3}X_{NeuAc}
1192.9 174.0

Annotations:

Y^{3,5}X_{Fuc} Y^{3,5}X_{Fuc}
1195.4 160.0
1196.0 261.0
1200.5 130.0

Annotations:

C
1202.4 180.0
1204.9 205.0
1212.4 209.0

Annotations:

Z Z
1212.8 198.0

Annotations:

Z Z
1213.5 105.0

Annotations:

B^{1,4}X_{GlcNAc} ^{0,3}A_{GlcNAc}Z
1214.0 104.0
1219.5 245.0
1220.5 115.0
1221.5 548.0

Annotations:

Y Y
1222.0 447.0
1222.4 290.0
1222.8 230.0
1224.1 207.0

Annotations:

ZZ ZZ ZZ ZZ
1243.9 102.0

Annotations:

^{2,4}X_{NeuAc}Y ^{2,4}X_{NeuAc}Y ^{0,2}A_{GlcNAc}Z
1256.6 199.0

Annotations:

^{0,2}X_{NeuAc} ^{0,2}X_{NeuAc}
1256.8 116.0

Annotations:

^{0,2}X_{NeuAc} ^{0,2}X_{NeuAc}
1259.0 126.0
1266.0 217.0
1268.0 122.0

Annotations:

^{2,5}A_{Man}Z
1276.4 257.0
1277.0 269.0
1278.6 145.0
1285.4 132.0

Annotations:

Z
1286.0 211.0

Annotations:

^{2,5}A_{Man}Y
1286.5 267.0

Annotations:

^{2,5}A_{Man}Y
1287.0 300.0
1294.4 161.0

Annotations:

Y
1295.0 177.0
1298.1 180.0

Annotations:

^{1,5}A_{GlcNAc}Z ^{1,5}A_{Man}Z
1305.0 240.0
1307.0 221.0

Annotations:

^{0,4}X_{NeuAc} ^{0,4}X_{NeuAc}
1307.9 111.0

Annotations:

^{1,5}X_{Fuc}
1316.2 194.0

Annotations:

^{1,5}A_{GlcNAc}Y ^{1,5}A_{Man}Y ^{2,4}X_{NeuAc} ^{2,4}X_{NeuAc}
1319.0 144.0
1328.5 283.0

Annotations:

Z^{2,5}X_{NeuAc}
1328.9 120.0

Annotations:

Z^{2,5}X_{NeuAc}
1329.5 462.0

Annotations:

^{0,3}X_{Fuc}
1330.0 157.0

Annotations:

^{0,3}X_{Fuc} Y^{0,2}X_{NeuAc}
1331.3 228.0
1337.1 605.0

Annotations:

^{1,3}X_{Fuc} ^{2,4}X_{Fuc}
1337.5 837.0

Annotations:

^{3,5}X_{Fuc}
1338.1 464.0

Annotations:

^{3,5}X_{Fuc}
1338.5 353.0
1339.0 243.0
1346.6 251.0

Annotations:

Y^{2,5}X_{NeuAc}
1346.9 305.0

Annotations:

Y^{2,5}X_{NeuAc}
1347.5 258.0
1350.0 201.0
1350.4 129.0
1356.9 449.0
1357.5 536.0
1358.0 2267.0

Annotations:

Z^{3,5}X_{NeuAc}
1358.5 1873.0

Annotations:

Z^{3,5}X_{NeuAc}
1359.1 1188.0

Annotations:

^{2,5}X_{GlcNAc}Y Y^{2,5}X_{GlcNAc} ^{2,5}X_{GlcNAc}Y
1359.5 374.0

Annotations:

^{2,5}X_{GlcNAc}Y Y^{2,5}X_{GlcNAc} ^{2,5}X_{GlcNAc}Y
1360.0 315.0

Annotations:

^{2,5}X_{GlcNAc}Y Y^{2,5}X_{GlcNAc} ^{2,5}X_{GlcNAc}Y Y^{0,3}X_{NeuAc}
1360.4 240.0

Annotations:

Y^{0,3}X_{NeuAc}
1365.5 275.0
1365.9 1309.0
1366.5 1036.0
1367.1 4061.0
1367.5 2031.0
1431.4 155.0

Annotations:

Y^{0,4}X_{NeuAc}
1473.3 138.0

Annotations:

B^{3,5}X_{GlcNAc} Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} Z^{1,5}X_{Man} ^{1,5}X_{Gal}Z
1473.6 140.0

Annotations:

B^{3,5}X_{GlcNAc} Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} Z^{1,5}X_{Man} ^{1,5}X_{Gal}Z
1474.6 137.0

Annotations:

Z^{0,2}X_{NeuAc}
1696.7 133.0

Annotations:

^{3,5}X_{GlcNAc}Y
1727.8 117.0

Annotations:

CY CY CY CY
1773.8 164.0
1783.6 137.0

Annotations:

^{3,5}A_{GlcNAc}Y ^{3,5}A_{GlcNAc}Y ^{1,4}X_{NeuAc}Z Z^{1,4}X_{NeuAc}
1790.7 139.0
1839.8 138.0

Annotations:

^{0,2}X_{NeuAc}Z Z^{0,2}X_{NeuAc}
1854.6 175.0

Annotations:

^{1,3}X_{Man}Z Z^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Z ^{1,3}X_{Gal}Z Z^{0,4}X_{Fuc} Z^{1,3}X_{NeuAc}
1874.7 163.0
1875.6 150.0
1906.2 143.0
1992.8 197.0
2009.0 116.0
2062.6 138.0

Annotations:

^{1,5}X_{NeuAc}Y Y^{1,5}X_{NeuAc}
2078.8 102.0

Annotations:

Y Y
2079.9 109.0

Annotations:

C^{2,4}X_{NeuAc} C^{2,4}X_{NeuAc}
2081.8 141.0
2092.7 127.0

Annotations:

CY CY
2153.8 108.0

There are 3 similar spectra:

Id Structure Score

2578

1.00

2425

0.55

2424

0.55
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