In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.

PubMed Entry

GlyToucan Accession Number: G58117BV

Peak Intensity
470.1 121.0

Annotations:

C
552.1 210.0

Annotations:

^{0,4}A_{Man}Z B^{0,2}X_{Gal}
695.3 245.0
782.7 472.0

Annotations:

CY
815.8 638.0

Annotations:

BZ
818.1 110.0

Annotations:

B^{1,4}X_{GlcNAc} ^{0,3}A_{GlcNAc}Z B^{0,3}X_{Gal} ^{1,4}A_{GlcNAc}Y C^{1,4}X_{Man} Y^{1,5}X_{Gal} ^{1,5}X_{Gal}Y
821.5 137.0
830.3 167.0
851.3 130.0
893.3 236.0

Annotations:

YY YY YY
920.3 182.0

Annotations:

Z^{3,5}X_{Fuc} ^{1,5}X_{NeuAc}Z ^{2,5}A_{GlcNAc}Z ^{2,5}A_{Man}Z ^{1,4}X_{GlcNAc}Z ^{1,4}X_{GlcNAc}Z Z^{0,3}X_{Fuc} Z^{3,5}X_{Gal} Z^{0,3}X_{Fuc}
928.3 213.0

Annotations:

Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} C^{0,3}X_{Gal} ^{1,4}A_{GlcNAc}Y ^{0,2}X_{NeuAc}Y Z^{3,5}X_{Fuc} Z^{3,5}X_{Fuc}
937.3 394.0

Annotations:

^{0,2}A_{GlcNAc} C^{2,4}X_{NeuAc} Y^{3,5}X_{Fuc} Y^{3,5}X_{Fuc}
957.5 457.0

Annotations:

Z Y
957.8 166.0

Annotations:

Z Y
958.0 809.0

Annotations:

Y
958.4 334.0

Annotations:

C^{1,5}X_{Fuc}
959.0 445.0
980.3 434.0

Annotations:

C^{0,3}X_{Fuc} C^{3,5}X_{Gal} ^{1,5}X_{GlcNAc} Y^{1,5}X_{Fuc} ^{0,3}A_{GlcNAc}Y
1009.8 186.0

Annotations:

C^{0,3}X_{NeuAc} C^{1,5}X_{NeuAc} ^{1,5}A_{GlcNAc}Y Y^{3,5}X_{Fuc}
1010.3 113.0

Annotations:

Y^{3,5}X_{Fuc}
1017.8 385.0

Annotations:

C
1019.4 220.0

Annotations:

BZ BZ
1030.3 198.0

Annotations:

Z
1038.3 504.0

Annotations:

C
1038.8 1890.0

Annotations:

C Y
1039.4 2571.0

Annotations:

YZ ZY
1039.8 945.0

Annotations:

YZ ZY
1040.3 430.0
1040.9 424.0
1058.0 159.0

Annotations:

ZZ ZZ
1059.9 321.0

Annotations:

C^{1,5}X_{Fuc} ^{2,5}A_{GlcNAc}
1060.2 449.0

Annotations:

C^{1,5}X_{Fuc} ^{2,5}A_{GlcNAc}
1086.4 191.0

Annotations:

^{0,3}A_{GlcNAc}Y C^{1,4}X_{GlcNAc}
1089.4 202.0

Annotations:

C^{3,5}X_{Fuc} Y^{1,5}X_{Fuc} Y^{1,5}X_{Fuc}
1092.4 208.0
1094.5 588.0

Annotations:

^{1,5}X_{NeuAc}Z Z^{1,4}X_{Fuc} Z^{1,4}X_{Fuc} Z^{0,3}X_{Gal} Z^{1,4}X_{Gal}
1094.9 495.0

Annotations:

^{1,5}X_{NeuAc}Z Z^{1,4}X_{Fuc} Z^{1,4}X_{Fuc} Z^{0,3}X_{Gal} Z^{1,4}X_{Gal} B^{2,5}X_{GlcNAc}
1102.9 566.0

Annotations:

^{1,5}X_{NeuAc}Z ^{1,5}X_{NeuAc}Z ^{0,2}X_{NeuAc}Y Z^{0,3}X_{Fuc} Z^{0,3}X_{Fuc} Z^{3,5}X_{Gal}
1108.0 461.0

Annotations:

Z^{1,5}X_{Man} ^{1,5}X_{Gal}Z
1108.6 196.0

Annotations:

^{1,5}X_{Gal}Z Z^{1,5}X_{Man} ^{0,3}X_{NeuAc}Z
1110.4 486.0

Annotations:

Z^{1,3}X_{Gal} Z^{2,4}X_{Gal} ^{1,4}A_{Man} ^{0,2}X_{NeuAc}Y ^{0,2}X_{NeuAc}Y ^{2,5}X_{NeuAc}Y Z^{3,5}X_{Fuc} Z^{3,5}X_{Fuc} Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} Z^{0,4}X_{Gal}
1112.5 367.0
1113.6 295.0

Annotations:

C^{2,5}X_{GlcNAc}
1123.9 263.0

Annotations:

^{2,5}A_{Man}Z
1132.0 185.0
1140.2 103.0

Annotations:

Z
1148.4 125.0

Annotations:

YY
1149.4 224.0

Annotations:

Y
1172.4 109.0
1174.0 286.0

Annotations:

Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} ^{1,3}X_{Fuc}Z ^{2,4}X_{Fuc}Z
1175.0 324.0

Annotations:

^{0,3}X_{Fuc}Z Z^{0,3}X_{Fuc} ^{3,5}X_{Gal}Z Z^{3,5}X_{Gal} Z^{3,5}X_{Fuc} ^{3,5}X_{Fuc}Z
1185.6 240.0
1192.1 254.0

Annotations:

^{2,5}X_{NeuAc} ^{3,5}X_{Fuc}Y Y^{3,5}X_{Fuc}
1204.5 352.0

Annotations:

Z
1204.9 166.0

Annotations:

Z
1205.5 859.0
1212.5 1309.0

Annotations:

Z Z
1212.9 1519.0

Annotations:

Z Z
1213.4 1440.0

Annotations:

Y
1214.0 1431.0
1214.4 439.0
1215.0 543.0
1215.3 149.0
1219.6 324.0
1221.3 144.0

Annotations:

Y Y
1222.3 201.0
1234.6 101.0

Annotations:

^{0,2}X_{Gal} ^{0,4}X_{NeuAc}
1247.0 220.0
1259.0 282.0

Annotations:

^{2,4}A_{GlcNAc}Y
1264.5 2069.0

Annotations:

^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{1,3}X_{Fuc} ^{2,4}X_{Fuc}
1264.9 901.0

Annotations:

^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{1,3}X_{Fuc} ^{2,4}X_{Fuc}
1265.4 1017.0

Annotations:

^{3,5}X_{Fuc} ^{3,5}X_{Fuc}
1266.9 192.0
1273.3 166.0

Annotations:

^{3,5}A_{GlcNAc}Y
1273.5 484.0

Annotations:

^{3,5}A_{GlcNAc}Y
1274.1 708.0
1274.6 541.0
1275.1 612.0
1277.1 267.0
1277.5 347.0
1278.4 146.0
1284.9 570.0

Annotations:

Z^{0,2}X_{Fuc} Z^{0,2}X_{Fuc} Z^{2,5}X_{Gal}
1285.5 230.0

Annotations:

^{2,5}A_{GlcNAc}Z ^{2,5}A_{Man}Z
1287.1 313.0
1288.3 228.0

Annotations:

^{1,5}X_{GlcNAc}Y Y^{1,5}X_{Man} ^{1,5}X_{Man}Y Y^{1,5}X_{Fuc} ^{1,5}X_{Gal}Y ^{1,5}X_{Man}Y Y^{1,5}X_{Fuc}
1293.5 250.0
1294.0 1179.0
1294.4 1145.0
1295.0 464.0
1346.5 1115.0

Annotations:

C^{3,5}X_{GlcNAc} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{1,3}X_{Man}Y Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc}
1347.6 222.0
1551.6 159.0

Annotations:

^{3,5}X_{Gal}Y ^{3,5}X_{GlcNAc}Y ^{3,5}X_{GlcNAc}Y ^{3,5}X_{GlcNAc}Y
1586.5 102.0
1611.0 123.0

Annotations:

^{2,5}A_{GlcNAc}Y C^{1,5}X_{GlcNAc} C^{1,5}X_{Gal}
1710.8 137.0
1712.7 194.0
1716.0 138.0
1716.7 303.0
1812.6 388.0

Annotations:

^{2,5}A_{GlcNAc}Z Y^{0,2}X_{Fuc} B^{2,5}X_{NeuAc}
1834.7 403.0
1851.4 277.0
1934.6 472.0

Annotations:

C^{2,4}X_{NeuAc}
1935.7 139.0
2000.8 240.0

Annotations:

Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} ^{1,5}X_{Gal}Z ^{1,5}X_{Gal}Z Z^{1,5}X_{Fuc} Z^{1,5}X_{Fuc}
2035.8 442.0

Annotations:

C
2036.8 187.0
2037.0 129.0
2037.1 109.0
2037.8 263.0
2039.6 121.0
2042.0 234.0
2062.9 145.0

Annotations:

^{0,3}X_{Gal}Y ^{0,3}X_{Gal}Y ^{3,5}X_{Gal}Y Y^{0,3}X_{Fuc} Y^{0,3}X_{Fuc} Y^{3,5}X_{Gal} ^{3,5}X_{GlcNAc}
2063.9 287.0

Annotations:

C^{3,5}X_{NeuAc}
2064.8 287.0
2078.0 166.0

Annotations:

^{2,4}A_{GlcNAc}
2079.7 230.0
2198.9 261.0

There are 1 similar spectra:

Id Structure Score

2576

1.00
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