In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.

PubMed Entry

GlyToucan Accession Number: G62989ND

Peak Intensity
467.0 135.0

Annotations:

^{0,2}X_{Man}Y Y^{0,2}X_{Fuc} ^{2,5}X_{GlcNAc}
468.1 135.0

Annotations:

^{2,5}A_{GlcNAc}Z C^{2,5}X_{NeuAc} C^{1,5}X_{Man} ^{0,2}A_{GlcNAc} C^{2,4}X_{NeuAc} ^{2,5}A_{GlcNAc}Y
536.1 250.0
538.1 187.0
553.3 104.0

Annotations:

Z
571.2 142.0

Annotations:

Y
572.3 260.0

Annotations:

^{0,2}A_{GlcNAc} C^{1,5}X_{GlcNAc} C^{2,4}X_{NeuAc}
628.1 110.0

Annotations:

BY CZ
655.1 203.0

Annotations:

B
726.2 130.0
729.3 103.0

Annotations:

BY CZ BY CZ
789.4 294.0

Annotations:

BY CZ
817.1 355.0

Annotations:

B
817.4 289.0

Annotations:

B
835.2 415.0

Annotations:

C
836.3 280.0
859.3 218.0

Annotations:

ZZ ZZ
893.2 268.0

Annotations:

Y
893.7 254.0

Annotations:

Y
911.5 244.0

Annotations:

^{1,4}X_{Man}Z Z^{0,3}X_{Fuc}
935.4 321.0

Annotations:

B
955.8 135.0

Annotations:

BY CZ
965.7 305.0

Annotations:

YY
966.4 480.0
996.5 553.0
1008.7 132.0

Annotations:

^{0,3}X_{GlcNAc}Y Y^{0,3}X_{GlcNAc} C^{3,5}X_{Gal} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{1,5}X_{Gal} ^{1,5}X_{Gal} ^{1,3}X_{Man}
1017.4 144.0
1020.5 306.0

Annotations:

B
1021.5 137.0

Annotations:

ZZ
1037.5 909.0

Annotations:

^{2,4}X_{GlcNAc}Y ^{0,2}X_{NeuAc}Y ^{2,5}X_{NeuAc}Y Z^{3,5}X_{Fuc}
1038.2 455.0

Annotations:

C
1039.2 395.0

Annotations:

Y
1039.9 414.0
1045.3 113.0

Annotations:

^{0,3}X_{NeuAc}Y Z^{0,4}X_{Fuc}
1051.1 217.0
1053.3 126.0

Annotations:

BY CZ BY CZ
1062.5 169.0

Annotations:

ZZ ZZ
1076.4 240.0
1077.4 103.0
1098.4 181.0

Annotations:

YY YY
1109.3 361.0

Annotations:

^{0,4}X_{Gal}Z ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Z ^{3,5}A_{GlcNAc}Z
1109.8 124.0

Annotations:

^{3,5}A_{GlcNAc}Z ^{0,4}X_{Gal}Z ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Z
1110.5 490.0

Annotations:

^{1,4}A_{Man} ^{2,4}X_{GlcNAc} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{0,2}X_{NeuAc}
1118.9 316.0

Annotations:

^{2,5}X_{NeuAc}
1119.2 494.0

Annotations:

^{2,5}X_{NeuAc}
1120.0 204.0
1127.5 134.0

Annotations:

^{3,5}A_{GlcNAc}Y
1131.6 226.0

Annotations:

Z
1131.9 319.0

Annotations:

Z
1132.5 539.0
1140.0 408.0

Annotations:

Y
1140.4 721.0

Annotations:

Y
1140.7 509.0

Annotations:

Y
1141.0 387.0
1151.4 161.0
1161.3 174.0

Annotations:

^{0,2}X_{Gal} ^{0,4}X_{NeuAc}
1161.5 170.0

Annotations:

^{0,2}X_{Gal} ^{0,4}X_{NeuAc}
1169.9 549.0

Annotations:

^{1,5}A_{Man}Z ^{0,2}X_{Fuc} ^{2,5}X_{Gal}
1170.5 574.0

Annotations:

C^{2,5}X_{GlcNAc} ^{1,4}X_{Gal}Y Y^{1,4}X_{Man} ^{0,3}X_{GlcNAc}Y Y^{0,3}X_{GlcNAc} ^{1,4}X_{Man}Y Y^{1,4}X_{Fuc} Y^{0,3}X_{Gal} Y^{1,4}X_{Gal} ^{2,4}X_{NeuAc}
1174.5 290.0
1184.0 308.0

Annotations:

C^{0,3}X_{GlcNAc} ^{1,4}A_{GlcNAc}Y ^{0,3}X_{Fuc} ^{3,5}X_{Gal} Z^{3,5}X_{Fuc}
1184.6 286.0

Annotations:

C^{0,3}X_{GlcNAc} ^{1,4}A_{GlcNAc}Y ^{0,3}X_{Fuc} ^{3,5}X_{Gal} Z^{3,5}X_{Fuc}
1189.9 436.0
1191.3 380.0

Annotations:

^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal}
1191.8 581.0

Annotations:

^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal}
1192.4 805.0

Annotations:

^{3,5}X_{Fuc}
1200.3 295.0

Annotations:

C
1200.6 448.0

Annotations:

C
1200.9 582.0

Annotations:

C
1201.0 627.0
1201.5 634.0
1205.5 391.0
1206.4 230.0
1210.0 394.0

Annotations:

^{1,5}A_{GlcNAc}Z
1212.0 614.0
1212.3 1212.0
1212.6 708.0
1212.9 776.0
1213.4 434.0
1215.0 511.0

Annotations:

BY CZ
1218.5 100.0
1220.5 547.0
1220.9 299.0
1221.5 659.0
1238.3 210.0

Annotations:

BZ
1242.3 323.0

Annotations:

Z
1258.3 281.0

Annotations:

YZ ZY
1345.5 394.0
1346.7 318.0

Annotations:

^{1,4}A_{GlcNAc}Y C^{1,4}X_{Gal} C^{0,3}X_{GlcNAc} Z^{3,5}X_{Fuc}
1380.6 153.0
1383.7 147.0
1422.5 114.0

Annotations:

Y
1423.6 899.0
1547.3 361.0

Annotations:

BY CZ
1607.6 439.0

Annotations:

Z
1625.6 381.0

Annotations:

Y
1626.6 434.0

Annotations:

^{0,2}A_{GlcNAc}Y
1627.5 118.0
1658.5 172.0
1672.6 214.0
1709.6 144.0

Annotations:

BY CZ BY CZ
1712.6 286.0
1729.7 300.0

Annotations:

Y^{3,5}X_{Fuc}
1788.8 201.0

Annotations:

C^{2,4}X_{NeuAc}
1848.7 104.0
1872.7 395.0

Annotations:

Y^{1,5}X_{Fuc} ^{1,5}X_{Gal}Y ^{1,3}X_{Man}Y Y^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Y
1889.5 117.0

Annotations:

C
1889.8 105.0

Annotations:

C
1912.7 278.0

Annotations:

BY CZ
1915.6 319.0
1916.9 437.0

Annotations:

Y
1978.7 349.0
1990.5 248.0

Annotations:

Y
1992.8 226.0
1996.8 156.0
2074.8 238.0

Annotations:

B
2075.8 114.0

Annotations:

^{2,4}X_{GlcNAc}Y
2081.0 550.0
2092.8 282.0

Annotations:

C
2113.8 338.0
2153.9 712.0
2155.9 138.0
2158.0 177.0

There are 1 similar spectra:

Id Structure Score

2568

1.00
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