In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.

PubMed Entry

GlyToucan Accession Number: G74409IY

Peak Intensity
450.1 140.0

Annotations:

ZZ
470.0 170.0

Annotations:

C
528.2 109.0

Annotations:

C
620.8 162.0

Annotations:

YZ ZY
655.2 306.0

Annotations:

B
764.8 137.0

Annotations:

B^{3,5}X_{GlcNAc} ^{2,5}X_{NeuAc}Z ^{1,3}X_{Man}Z Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} Z^{0,4}X_{Gal} Z^{1,3}X_{Gal} Z^{2,4}X_{Gal} Z^{0,4}X_{GlcNAc} Z^{2,4}X_{GlcNAc}
774.3 167.0

Annotations:

YZ ZY
775.9 183.0
808.8 111.0

Annotations:

^{1,5}X_{Man}Z Z^{1,5}X_{Fuc} ^{1,5}X_{GlcNAc}Z Z^{1,5}X_{Gal}
816.4 591.0

Annotations:

BZ
817.0 137.0

Annotations:

B
817.3 220.0

Annotations:

B
835.3 918.0

Annotations:

C
836.3 562.0
842.3 201.0
855.3 209.0

Annotations:

CY
855.8 103.0

Annotations:

Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{2,4}X_{GlcNAc}Y Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{0,4}X_{GlcNAc} Y^{2,4}X_{GlcNAc} ^{1,3}X_{Man} ^{2,4}A_{GlcNAc}Y
856.2 136.0

Annotations:

YY
859.4 112.0

Annotations:

^{0,3}X_{GlcNAc}Z ^{0,3}X_{GlcNAc}Z ^{3,5}X_{GlcNAc}Z
875.9 237.0

Annotations:

Z
876.9 396.0

Annotations:

Y
879.0 182.0

Annotations:

C^{1,4}X_{NeuAc}
897.3 117.0

Annotations:

YZ ZY
906.9 190.0

Annotations:

^{2,4}X_{NeuAc}Y C^{3,5}X_{Fuc} ^{1,3}X_{GlcNAc}Y
927.9 111.0

Annotations:

Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{1,5}X_{Fuc} ^{1,3}X_{Man} ^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y ^{1,5}X_{Gal}Y ^{1,5}X_{Gal}Y Y^{1,5}X_{Fuc} C^{1,5}X_{NeuAc}
928.5 127.0

Annotations:

C^{1,5}X_{NeuAc} Y^{3,5}X_{Fuc}
928.9 144.0

Annotations:

Y^{3,5}X_{Fuc} ^{3,5}X_{Gal}Y
931.3 139.0
936.8 763.0

Annotations:

C
937.4 309.0
937.9 101.0
945.3 362.0
948.1 145.0

Annotations:

CZ BY ZZ
948.8 150.0

Annotations:

Z
957.4 1293.0

Annotations:

Y
957.9 2498.0

Annotations:

Y
958.4 1157.0
958.8 507.0
959.4 228.0
959.8 134.0
960.3 130.0
976.9 169.0

Annotations:

ZZ ZZ
978.8 307.0

Annotations:

B^{1,3}X_{GlcNAc} B^{2,4}X_{NeuAc} C^{1,5}X_{Fuc}
982.4 180.0
985.4 124.0

Annotations:

YZ ZY ZY YZ
986.8 117.0

Annotations:

Y
991.3 122.0
996.4 356.0
996.8 134.0
1005.3 342.0
1011.9 127.0
1012.1 116.0
1012.5 296.0

Annotations:

ZZ
1020.4 368.0

Annotations:

ZZ ZZ
1020.9 350.0

Annotations:

ZZ ZZ
1026.4 113.0
1027.5 137.0

Annotations:

^{0,3}X_{NeuAc}Z
1028.4 156.0

Annotations:

B
1029.4 268.0

Annotations:

YZ YZ ZY ZY
1030.0 180.0

Annotations:

YZ YZ ZY ZY
1032.7 112.0
1041.5 239.0

Annotations:

ZZ ZZ
1041.8 380.0

Annotations:

ZZ ZZ
1042.9 139.0

Annotations:

Z^{0,2}X_{Gal} ^{0,4}X_{NeuAc}Z
1050.5 125.0

Annotations:

YZ YZ ZY ZY
1050.9 454.0

Annotations:

Z^{0,2}X_{Fuc} Z^{0,2}X_{Fuc} Z^{2,5}X_{Gal}
1052.0 133.0

Annotations:

Y^{0,2}X_{Gal} ^{0,4}X_{NeuAc}Y ^{2,4}X_{NeuAc}Z
1066.9 107.0

Annotations:

YY
1069.0 110.0
1090.4 240.0
1090.8 115.0
1091.2 159.0
1102.9 111.0

Annotations:

Z
1103.5 494.0

Annotations:

^{0,3}X_{Fuc}Y Y^{0,3}X_{Fuc} ^{3,5}X_{Gal}Y Y^{3,5}X_{Gal} Y^{3,5}X_{Fuc} ^{3,5}X_{Fuc}Y ^{3,5}X_{GlcNAc}Y ^{3,5}X_{GlcNAc}Y ^{1,5}X_{NeuAc}
1105.0 187.0
1111.5 218.0

Annotations:

Y
1111.9 300.0

Annotations:

Y
1112.4 369.0

Annotations:

Y
1112.8 171.0
1118.6 128.0

Annotations:

^{0,4}X_{Fuc}Y Y^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Y ^{1,3}X_{NeuAc}Y
1124.5 175.0
1131.4 1059.0

Annotations:

Z Z
1132.0 921.0

Annotations:

Y
1132.5 1756.0

Annotations:

Y
1133.0 1330.0
1133.4 1277.0
1134.4 184.0
1140.5 392.0

Annotations:

Y Y
1141.0 462.0

Annotations:

^{2,5}A_{GlcNAc}Y ^{2,5}A_{Man}Y
1141.4 279.0

Annotations:

^{2,5}A_{GlcNAc}Y ^{2,5}A_{Man}Y
1142.4 103.0
1143.8 267.0
1152.3 115.0

Annotations:

^{1,4}X_{GlcNAc}Z Z^{1,4}X_{Man} ^{1,4}X_{Man}Z
1153.5 245.0

Annotations:

^{1,5}A_{Man}Z ^{0,2}X_{Gal} ^{0,2}X_{GlcNAc} ^{0,4}X_{NeuAc}
1162.9 232.0

Annotations:

^{1,3}X_{GlcNAc} ^{2,4}X_{NeuAc}
1163.9 101.0

Annotations:

BZ
1177.6 121.0
1182.9 153.0

Annotations:

BY CZ
1183.5 1198.0

Annotations:

^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{GlcNAc} ^{2,4}X_{GlcNAc}
1184.0 1133.0

Annotations:

^{3,5}X_{Fuc} ^{3,5}X_{Fuc}
1184.5 268.0

Annotations:

^{3,5}X_{Fuc} ^{3,5}X_{Fuc}
1185.0 131.0
1192.4 662.0
1193.0 719.0

Annotations:

^{0,3}X_{GlcNAc}Z
1193.4 382.0

Annotations:

^{0,3}X_{GlcNAc}Z
1193.5 534.0

Annotations:

^{0,3}X_{GlcNAc}Z
1194.0 151.0

Annotations:

^{1,5}A_{GlcNAc}Z
1194.5 151.0

Annotations:

^{1,5}A_{GlcNAc}Z
1204.0 697.0
1204.6 198.0
1205.5 286.0
1212.4 106.0

Annotations:

^{1,5}A_{GlcNAc}Y
1213.0 1393.0
1213.5 919.0
1213.8 116.0
1214.9 232.0
1224.3 130.0

Annotations:

ZZ
1445.6 168.0

Annotations:

YZ ZY YZ ZY YZ YZ ZY ZY
1487.6 100.0

Annotations:

B^{1,3}X_{Man} Z^{0,2}X_{Fuc} Z^{0,2}X_{Fuc} Z^{2,5}X_{Gal} Z^{2,5}X_{GlcNAc} ^{0,2}X_{Gal}Z
1547.4 193.0

Annotations:

BY CZ
1547.7 177.0

Annotations:

BY CZ
1565.9 260.0

Annotations:

CY
1568.2 144.0

Annotations:

YY
1571.6 168.0
1572.5 221.0

Annotations:

ZZ
1609.9 195.0

Annotations:

Y
1611.5 152.0
1611.7 160.0
1693.5 113.0

Annotations:

BY CZ
1695.6 112.0

Annotations:

YZ ZY
1696.7 259.0

Annotations:

Y^{3,5}X_{Fuc}
1738.8 160.0

Annotations:

^{2,5}A_{GlcNAc}Z ^{0,3}X_{GlcNAc}Y ^{0,3}X_{GlcNAc}Y ^{3,5}X_{GlcNAc}Y
1793.8 101.0
1856.8 114.0

Annotations:

Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{1,5}X_{Fuc} ^{1,3}X_{Man} ^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y ^{1,5}X_{Gal}Y ^{1,5}X_{Gal}Y Y^{1,5}X_{Fuc}
1857.7 207.0

Annotations:

C^{1,5}X_{NeuAc}
1863.7 108.0
1873.7 566.0

Annotations:

C
1873.9 264.0

Annotations:

C
1874.5 265.0
1874.8 392.0
1875.4 190.0
1875.7 176.0
1875.9 104.0
1876.8 342.0
1898.6 224.0

Annotations:

Z
1916.7 153.0

Annotations:

Y
1917.7 133.0
1918.8 111.0
1918.9 104.0
1975.9 145.0

Annotations:

C^{1,3}X_{GlcNAc} C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc}
2026.0 177.0
2058.6 171.0

Annotations:

B
2059.0 146.0

Annotations:

B
2059.8 339.0
2060.7 208.0

Annotations:

ZY YZ YZ ZY
2078.0 108.0
2078.7 110.0

Annotations:

YY YY
2079.8 111.0
2135.8 266.0

Annotations:

YY
2136.8 468.0

Annotations:

Y
2137.6 142.0
2137.9 179.0
2138.7 202.0
2177.8 139.0

Annotations:

^{0,2}X_{Fuc}Y Y^{0,2}X_{Fuc} ^{2,5}X_{Gal}Y Y^{2,5}X_{Gal} Y^{2,5}X_{Fuc} ^{2,5}X_{Fuc}Y ^{2,5}X_{GlcNAc}Y ^{2,5}X_{GlcNAc}Y

There are 2 similar spectra:

Id Structure Score

2564

1.00

2411

0.75
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