In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.

PubMed Entry

GlyToucan Accession Number: G25827MU

Peak Intensity
419.2 104.0
545.0 132.0
571.3 101.0

Annotations:

Y
572.2 295.0

Annotations:

C^{1,5}X_{GlcNAc} C^{1,5}X_{Fuc} C^{2,4}X_{NeuAc}
573.5 431.0
612.3 129.0

Annotations:

B^{0,4}X_{Gal} B^{1,3}X_{Gal} B^{2,4}X_{Gal} B^{1,3}X_{Fuc} B^{2,4}X_{Fuc}
648.2 185.0
675.3 299.0
816.3 399.0

Annotations:

^{2,5}A_{GlcNAc}Z B^{1,5}X_{Gal} ^{0,2}X_{GlcNAc}Z Z^{0,2}X_{Gal} Z^{0,2}X_{GlcNAc} C^{1,5}X_{Man}
855.3 116.0

Annotations:

C^{3,5}X_{GlcNAc} Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{2,4}X_{GlcNAc}Y Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} Y^{0,4}X_{GlcNAc} Y^{2,4}X_{GlcNAc} ^{1,3}X_{Man}
857.2 241.0
874.1 273.0

Annotations:

BZ BZ
904.5 138.0

Annotations:

YZ ZY YZ YZ ZY ZY
907.0 350.0
926.9 482.0

Annotations:

BY CZ
937.3 384.0

Annotations:

C^{2,4}X_{NeuAc}
977.4 618.0

Annotations:

Z
1023.2 208.0

Annotations:

^{0,3}X_{GlcNAc}Y Y^{1,4}X_{Fuc} Y^{1,4}X_{Fuc} Y^{0,3}X_{Gal} Y^{1,4}X_{Gal} Y^{0,3}X_{GlcNAc} ^{1,4}X_{Gal}
1029.5 438.0

Annotations:

Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{1,3}X_{Man} ^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y C^{1,5}X_{NeuAc} Z^{3,5}X_{Fuc} Z^{3,5}X_{Fuc}
1029.8 252.0

Annotations:

^{0,4}X_{GlcNAc}Y Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{1,3}X_{Man} ^{2,4}X_{GlcNAc}Y C^{1,5}X_{NeuAc} Z^{3,5}X_{Fuc} Z^{3,5}X_{Fuc}
1030.7 749.0

Annotations:

Y^{3,5}X_{Fuc} ^{3,5}X_{GlcNAc}Y Y^{0,3}X_{Fuc} Y^{0,3}X_{Fuc} Y^{3,5}X_{Gal} Y^{3,5}X_{GlcNAc}
1038.3 297.0

Annotations:

C C
1038.6 130.0

Annotations:

C
1039.3 233.0

Annotations:

Y^{3,5}X_{Fuc} Y^{3,5}X_{Fuc}
1051.4 250.0

Annotations:

^{0,3}X_{GlcNAc}Y ^{0,3}X_{GlcNAc}Y ^{3,5}X_{GlcNAc}Y C^{3,5}X_{NeuAc} C^{1,5}X_{GlcNAc}
1058.8 332.0

Annotations:

Z
1059.5 1274.0

Annotations:

Y
1059.9 550.0
1060.3 1455.0
1111.0 236.0

Annotations:

^{2,5}X_{NeuAc}Y ^{3,5}A_{GlcNAc}Y
1113.9 498.0
1122.7 339.0

Annotations:

ZZ ZZ
1122.9 404.0

Annotations:

ZZ ZZ
1127.8 351.0

Annotations:

^{0,3}A_{GlcNAc}Y C^{1,4}X_{Man}
1128.0 112.0
1128.5 243.0
1130.2 315.0

Annotations:

B
1134.8 465.0
1142.9 347.0

Annotations:

ZZ ZZ
1145.9 334.0

Annotations:

Z^{1,5}X_{Fuc} ^{3,5}X_{NeuAc}Z ^{3,5}X_{NeuAc}Z ^{1,5}X_{GlcNAc}Z ^{1,5}X_{GlcNAc}Z Z^{1,5}X_{Fuc}
1192.5 306.0
1210.0 122.0
1213.5 160.0

Annotations:

Y
1213.9 712.0

Annotations:

Y
1215.0 829.0
1233.6 296.0

Annotations:

Y
1234.6 1638.0
1235.0 347.0
1242.0 183.0

Annotations:

Y Y
1242.5 852.0

Annotations:

YZ ZY
1243.0 150.0
1243.5 314.0
1244.7 272.0
1284.8 218.0

Annotations:

^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{GlcNAc} ^{2,4}X_{GlcNAc}
1285.1 564.0

Annotations:

^{1,3}X_{Fuc} ^{2,5}A_{GlcNAc}Z ^{2,4}X_{Fuc} ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{GlcNAc} ^{2,4}X_{GlcNAc}
1285.5 573.0

Annotations:

^{2,5}A_{GlcNAc}Z ^{3,5}X_{Fuc} ^{3,5}X_{Fuc}
1285.9 462.0

Annotations:

^{2,5}A_{GlcNAc}Z ^{3,5}X_{Fuc} ^{3,5}X_{Fuc}
1287.3 390.0
1294.0 215.0
1294.5 100.0
1294.8 285.0
1295.4 268.0
1305.6 1125.0
1306.5 1038.0
1315.1 205.0
1369.6 676.0
1570.7 430.0

Annotations:

BZ
1606.3 345.0

Annotations:

CY
1645.9 107.0
1726.7 118.0
1729.7 156.0
1771.9 464.0

Annotations:

Y
1898.7 397.0

Annotations:

YZ ZY
1916.5 163.0

Annotations:

YY
1940.7 123.0

Annotations:

B^{1,5}X_{Fuc}
2077.0 132.0

Annotations:

C
2079.1 470.0

Annotations:

Y^{3,5}X_{Fuc} Y^{3,5}X_{Fuc}
2079.8 115.0
2101.8 103.0

Annotations:

Z
2119.0 327.0

Annotations:

Z
2119.8 154.0

Annotations:

Y
2122.5 311.0

There are 1 similar spectra:

Id Structure Score

2598

1.00
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