In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.

PubMed Entry

GlyToucan Accession Number: G46208AF

Peak Intensity
350.1 154.0

Annotations:

Z
389.3 139.0

Annotations:

ZZ
508.2 117.0

Annotations:

BZ
553.3 393.0

Annotations:

Z
600.6 147.0
644.8 208.0
655.3 357.0

Annotations:

B
656.2 188.0

Annotations:

^{3,5}A_{GlcNAc}Z ^{1,4}A_{GlcNAc}Y
671.7 234.0

Annotations:

CZ CZ BY BY
702.2 178.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y B^{1,4}X_{NeuAc} Y^{3,5}X_{Fuc}
758.8 336.0

Annotations:

^{1,5}A_{GlcNAc}Y ^{1,5}A_{GlcNAc}Y ^{1,5}A_{Man}
793.3 142.0

Annotations:

Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} Z^{0,4}X_{GlcNAc} Z^{2,4}X_{GlcNAc} Z^{0,4}X_{GlcNAc} Z^{2,4}X_{GlcNAc}
803.3 509.0

Annotations:

YZ YZ ZY ZY YY
803.9 320.0

Annotations:

YY
804.3 153.0
835.3 796.0

Annotations:

C
836.4 185.0
845.8 284.0

Annotations:

^{1,5}A_{Man}Z ^{1,3}X_{Man}Z Z^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Z Z^{1,5}X_{Fuc} ^{2,5}X_{NeuAc}Z ^{2,5}X_{NeuAc}Z
854.8 304.0

Annotations:

^{2,5}X_{NeuAc}Y ^{2,5}X_{NeuAc}Y Z^{1,3}X_{GlcNAc} Z^{1,3}X_{GlcNAc} ^{1,3}X_{Man}Y Y^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}Y Y^{1,5}X_{Fuc}
875.7 136.0

Annotations:

YZ ZY YZ ZY
876.3 387.0

Annotations:

YZ ZY YZ ZY
878.2 258.0
886.1 170.0

Annotations:

^{1,5}A_{GlcNAc}Z
889.9 215.0

Annotations:

^{1,5}X_{GlcNAc}Z Z^{1,5}X_{Fuc} ^{1,5}X_{GlcNAc}Z Z^{1,5}X_{Fuc} ^{3,5}X_{NeuAc}Z
896.5 107.0

Annotations:

Z^{0,2}X_{Fuc} Z^{0,2}X_{Fuc} ^{2,5}X_{GlcNAc}Z Z^{2,5}X_{GlcNAc}
937.3 243.0

Annotations:

C^{1,5}X_{GlcNAc}
944.5 283.0
947.4 218.0

Annotations:

^{3,5}A_{GlcNAc}Z ^{0,4}X_{GlcNAc}Z ^{2,4}X_{GlcNAc}Z ^{0,4}X_{GlcNAc}Z ^{2,4}X_{GlcNAc}Z
947.9 450.0
957.8 469.0

Annotations:

Y Y
958.5 153.0
959.3 194.0
961.3 363.0
962.3 250.0
977.3 639.0

Annotations:

Z
977.8 1219.0

Annotations:

Z
978.4 463.0

Annotations:

C^{1,5}X_{Man}
985.9 210.0

Annotations:

Y
993.5 329.0

Annotations:

^{0,2}A_{GlcNAc}Z ^{1,4}X_{GlcNAc} ^{1,4}X_{GlcNAc}
999.0 237.0

Annotations:

^{0,2}X_{GlcNAc} ^{0,2}X_{GlcNAc} ^{0,4}X_{NeuAc}
1001.3 176.0
1004.3 162.0

Annotations:

B^{1,4}X_{Man} ^{1,4}A_{GlcNAc}Z B^{0,3}X_{GlcNAc}
1005.1 123.0
1016.2 293.0
1020.3 283.0

Annotations:

B^{3,5}X_{GlcNAc} ^{1,3}X_{Man}Z Z^{1,3}X_{Man}
1029.7 151.0

Annotations:

^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{GlcNAc} ^{2,4}X_{GlcNAc} ^{0,4}X_{GlcNAc} ^{2,4}X_{GlcNAc}
1030.0 599.0

Annotations:

^{3,5}X_{Fuc}
1030.5 532.0

Annotations:

^{3,5}X_{Fuc}
1038.4 121.0

Annotations:

C^{3,5}X_{GlcNAc} ^{1,3}X_{Man}Y Y^{1,3}X_{Man}
1038.9 233.0
1265.5 155.0

Annotations:

ZZ
1303.7 192.0
1326.5 204.0

Annotations:

BZ BZ
1363.5 119.0
1364.4 109.0
1388.5 241.0
1464.7 176.0

Annotations:

C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc}Y ^{0,2}A_{GlcNAc}Y C^{1,3}X_{GlcNAc} C^{1,3}X_{GlcNAc}
1467.5 280.0
1516.6 115.0
1518.9 216.0
1530.6 135.0

Annotations:

^{1,5}X_{Gal}Z Z^{1,5}X_{Fuc}
1547.6 160.0

Annotations:

B
1548.5 192.0

Annotations:

^{1,5}X_{Gal}Y Y^{1,5}X_{Fuc}
1549.5 141.0

Annotations:

C^{1,5}X_{NeuAc} ^{2,5}X_{NeuAc}Y
1565.5 461.0

Annotations:

C
1565.7 352.0

Annotations:

C
1566.5 203.0
1568.6 333.0
1650.6 134.0

Annotations:

Y^{0,2}X_{Fuc} ^{2,5}X_{GlcNAc}Y
1666.8 232.0

Annotations:

Y
1668.8 198.0
1718.6 286.0
1750.7 279.0

Annotations:

B
1751.7 335.0
1752.5 123.0

Annotations:

YZ ZY YZ ZY
1756.7 229.0
1768.7 175.0

Annotations:

C
1769.8 117.0
1828.8 235.0

Annotations:

Y
1830.9 177.0
1860.8 202.0
2003.6 347.0

There are 4 similar spectra:

Id Structure Score

2250

0.64

377

0.61

2373

0.51

2375

0.50
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