In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.

PubMed Entry

GlyToucan Accession Number: G69159WK

Peak Intensity
368.0 281.0

Annotations:

Y
424.1 349.0

Annotations:

C^{0,2}X_{Gal} ^{1,5}A_{Gal} C^{1,3}X_{Man} ^{1,3}A_{Man}Y C^{2,4}X_{GlcNAc} ^{0,2}A_{Man}Y ^{0,4}A_{Man} ^{1,3}A_{Man}Y ^{2,4}A_{Man}Y
452.1 294.0

Annotations:

B
459.1 209.0

Annotations:

B^{1,5}X_{GlcNAc} B^{1,5}X_{Gal}
526.3 261.0

Annotations:

BY BY CZ CZ BY CZ
553.2 197.0

Annotations:

Z
571.2 477.0

Annotations:

Y
604.3 107.0

Annotations:

^{0,3}X_{GlcNAc}Z B^{1,5}X_{Man} ^{1,5}A_{GlcNAc}Z
654.4 265.0
655.3 551.0

Annotations:

B
692.7 395.0

Annotations:

ZZ
695.2 344.0

Annotations:

C^{1,5}X_{GlcNAc} C^{3,5}X_{NeuAc}
701.8 2155.0

Annotations:

YZ ZY YY
702.2 615.0

Annotations:

YZ ZY YY
702.6 731.0

Annotations:

YY
754.3 551.0
774.3 262.0

Annotations:

YZ ZY
786.8 672.0

Annotations:

^{0,4}X_{NeuAc}Z B^{2,5}X_{GlcNAc} ^{1,4}X_{Man}Z Z^{1,4}X_{Man}
810.3 281.0

Annotations:

^{1,4}X_{GlcNAc}Z Z^{0,3}X_{Fuc}
815.8 203.0

Annotations:

^{0,2}X_{GlcNAc}Z ^{0,4}X_{NeuAc}Z
817.4 1259.0

Annotations:

B
818.2 310.0

Annotations:

Z^{3,5}X_{Fuc} ^{1,4}X_{NeuAc}Z
835.3 2268.0

Annotations:

C
836.4 262.0
837.2 382.0
837.5 156.0
838.2 179.0
845.9 780.0

Annotations:

^{0,4}X_{GlcNAc}Z ^{2,4}X_{GlcNAc}Z
846.9 1141.0

Annotations:

Z
854.8 710.0

Annotations:

^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y ^{2,5}X_{NeuAc}
855.3 222.0

Annotations:

^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y ^{2,5}X_{NeuAc}
855.8 455.0
856.9 603.0
866.8 219.0
875.8 2253.0

Annotations:

Z
876.3 399.0

Annotations:

Z
876.6 219.0
876.8 860.0

Annotations:

^{2,4}A_{Man} ^{1,3}A_{Man}
878.0 256.0
884.9 598.0

Annotations:

Y
885.2 300.0

Annotations:

Y
886.3 286.0
918.4 199.0
927.8 241.0

Annotations:

^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{GlcNAc} ^{2,4}X_{GlcNAc}
928.0 210.0

Annotations:

^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{GlcNAc} ^{2,4}X_{GlcNAc}
928.3 762.0

Annotations:

^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{0,4}X_{GlcNAc} ^{2,4}X_{GlcNAc}
931.4 316.0
933.3 126.0

Annotations:

^{2,4}A_{GlcNAc}Z B^{0,2}X_{Gal}
935.8 530.0

Annotations:

^{0,4}X_{Fuc} ^{1,3}X_{NeuAc}
937.4 741.0

Annotations:

C^{1,5}X_{GlcNAc} C^{1,5}X_{Gal}
940.4 513.0
941.5 205.0
980.3 177.0

Annotations:

^{1,5}X_{Man}Y Y^{1,5}X_{Fuc}
1006.3 438.0

Annotations:

^{1,4}X_{Man}Z Z^{0,3}X_{Fuc} ^{3,5}X_{GlcNAc}Z Z^{3,5}X_{GlcNAc}
1020.5 164.0

Annotations:

B^{3,5}X_{GlcNAc} Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} ^{2,4}X_{GlcNAc}Z Z^{0,4}X_{GlcNAc} Z^{2,4}X_{GlcNAc}
1345.3 370.0

Annotations:

^{1,5}X_{Gal}Y Y^{1,5}X_{Fuc}
1345.6 608.0

Annotations:

^{1,5}X_{Gal}Y Y^{1,5}X_{Fuc}
1346.6 372.0

Annotations:

C^{1,5}X_{NeuAc} ^{2,5}X_{NeuAc}Y
1363.5 724.0
1364.3 205.0
1366.6 273.0
1404.8 253.0

Annotations:

YZ ZY
1425.5 138.0
1447.7 131.0

Annotations:

Y^{0,2}X_{Fuc}
1464.3 823.0

Annotations:

C^{1,3}X_{GlcNAc} C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc}
1525.4 348.0
1530.8 256.0
1547.6 208.0

Annotations:

B
1548.4 698.0
1550.6 243.0
1551.5 147.0

Annotations:

Y
1565.7 271.0

Annotations:

C
1566.6 327.0
1625.6 167.0

Annotations:

Y

There are 3 similar spectra:

Id Structure Score

423

0.64

2244

0.57

2336

0.56
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