In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.

PubMed Entry

GlyToucan Accession Number: G66257KQ

Peak Intensity
305.0 114.0

Annotations:

BZ
323.1 707.0

Annotations:

B B B
341.0 204.0

Annotations:

C C C
341.2 403.0

Annotations:

C C C
343.1 713.0
382.9 109.0

Annotations:

^{1,3}A_{Man}Y ^{1,3}A_{Man} ^{1,3}A_{Man} ^{2,4}A_{Man} ^{0,4}A_{Man} ^{0,2}A_{GlcNAc}Y ^{2,4}A_{Man}Y ^{0,2}A_{Man}
383.3 190.0

Annotations:

^{0,2}A_{GlcNAc}Y ^{0,2}A_{Man} ^{0,4}A_{Man} ^{1,3}A_{Man} ^{1,3}A_{Man} ^{2,4}A_{Man} ^{1,3}A_{Man}Y ^{2,4}A_{Man}Y
411.7 129.0
420.9 169.0
425.4 184.0

Annotations:

Y
426.1 141.0
449.2 146.0

Annotations:

^{0,3}A_{Man}
451.2 221.0
467.1 416.0

Annotations:

BZ BZ
485.1 796.0

Annotations:

B
486.0 269.0
488.0 224.0
515.2 730.0

Annotations:

^{2,4}A_{GlcNAc}Y
515.8 409.0
516.7 238.0
527.1 171.0

Annotations:

Z
548.4 183.0
564.1 111.0

Annotations:

^{1,5}A_{GlcNAc}Z
587.3 354.0

Annotations:

YY
587.8 129.0
596.2 1303.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y
596.6 1407.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y
597.2 315.0
611.1 210.0

Annotations:

^{0,3}A_{GlcNAc}Y ^{0,3}A_{GlcNAc}Y ^{0,3}A_{GlcNAc}Y
624.9 229.0
629.4 333.0

Annotations:

BZ BZ BZ
647.4 125.0

Annotations:

BY BY BY BY CZ CZ CZ CZ BY BY CZ CZ
647.8 182.0
648.2 188.0
664.9 161.0

Annotations:

CY CY CY
665.2 273.0

Annotations:

CY CY CY
666.2 109.0
667.8 246.0

Annotations:

BY BY BY CZ CZ CZ
668.3 691.0

Annotations:

^{2,4}A_{GlcNAc}Z ^{2,4}A_{GlcNAc}Z ^{2,4}A_{GlcNAc}Z
668.8 919.0
669.3 163.0
669.8 210.0
670.3 193.0
677.3 2266.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y
677.7 1954.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y
678.3 636.0
678.8 345.0
679.4 294.0
697.8 360.0

Annotations:

Y
698.3 550.0

Annotations:

Y
698.9 526.0

Annotations:

^{2,5}A_{GlcNAc}Y ^{2,5}A_{GlcNAc}Y ^{2,5}A_{GlcNAc}Y ^{2,5}A_{Man}
699.3 302.0

Annotations:

^{2,5}A_{GlcNAc}Y ^{2,5}A_{GlcNAc}Y ^{2,5}A_{GlcNAc}Y ^{2,5}A_{Man}
707.2 413.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{0,4}A_{Man}Y ^{0,4}A_{Man}Y ^{0,2}A_{GlcNAc}Y ^{0,2}A_{GlcNAc}Y ^{0,2}A_{GlcNAc}Y ^{0,2}A_{Man}
719.2 256.0

Annotations:

^{0,3}A_{GlcNAc}Z ^{0,3}A_{Man}Z ^{0,3}A_{Man}Z
720.2 271.0
728.8 432.0
729.1 213.0
729.3 223.0
729.7 284.0
737.0 139.0

Annotations:

C
738.1 353.0
741.3 194.0
748.7 240.0

Annotations:

BY BY BY CZ CZ CZ
749.0 179.0

Annotations:

BY BY BY CZ CZ CZ YY
749.3 1354.0

Annotations:

YY
749.9 372.0
750.3 887.0
750.8 356.0

Annotations:

^{2,5}A_{GlcNAc}Y ^{2,5}A_{Man}
755.2 275.0
757.3 342.0

Annotations:

CY CY CY
758.3 3635.0

Annotations:

^{2,4}A_{GlcNAc}
758.8 2224.0
759.3 1272.0
759.8 124.0

Annotations:

^{1,4}A_{GlcNAc}Z
760.3 314.0

Annotations:

^{1,4}A_{GlcNAc}Z
770.3 264.0

Annotations:

Z Z Z
779.3 2325.0

Annotations:

Y Y Y
779.8 942.0

Annotations:

^{2,5}A_{GlcNAc}
780.3 1157.0

Annotations:

^{2,5}A_{GlcNAc}
781.7 188.0

Annotations:

^{1,5}A_{Man}
787.8 162.0

Annotations:

^{0,2}A_{GlcNAc}
788.8 122.0
790.3 184.0
791.5 416.0
800.3 450.0
800.4 291.0
801.3 187.0
805.3 179.0
809.3 1791.0

Annotations:

B
809.9 269.0
810.4 747.0
811.0 137.0
811.3 264.0
812.0 336.0
812.5 227.0
813.8 236.0
821.4 339.0
827.3 1242.0

Annotations:

C
828.3 576.0
829.2 158.0
829.8 544.0

Annotations:

B
830.3 1156.0
830.8 1372.0
831.3 807.0
832.3 115.0

Annotations:

BZ
839.3 207.0
839.6 492.0
839.9 594.0
840.2 250.0
840.4 376.0
840.7 292.0
851.4 191.0

Annotations:

Z Z Z
852.0 287.0
858.3 468.0
859.4 199.0
859.8 307.0

Annotations:

Y Y Y
860.4 3276.0

Annotations:

Y Y Y
860.8 2136.0
861.4 1518.0
861.7 402.0
862.0 220.0
869.3 443.0

Annotations:

^{0,4}A_{Man}
871.3 183.0
871.5 131.0
880.8 344.0
881.4 345.0
881.9 684.0
882.3 546.0
882.8 285.0

Annotations:

^{3,5}A_{Man}
890.4 348.0
890.9 288.0
891.2 146.0
891.5 765.0
899.0 105.0

Annotations:

^{0,3}A_{Man}
899.5 171.0

Annotations:

^{0,3}A_{Man}
911.4 2480.0

Annotations:

YY
911.9 705.0
912.3 863.0
912.8 311.0
920.4 707.0
920.9 858.0
921.3 914.0
921.5 231.0
921.8 140.0
922.3 308.0
931.4 922.0
931.9 467.0
932.2 281.0
932.8 228.0
953.4 366.0

Annotations:

BZ
954.2 252.0
969.3 104.0
971.3 376.0

Annotations:

BY CZ
972.1 182.0
972.4 202.0
973.2 332.0
974.2 122.0
995.4 162.0
1015.6 153.0
1031.5 116.0

Annotations:

^{2,4}A_{GlcNAc}Y
1055.4 107.0

Annotations:

Z
1073.3 172.0

Annotations:

Y
1117.6 119.0
1134.8 197.0
1193.4 136.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y
1194.3 183.0
1194.6 119.0
1235.5 279.0

Annotations:

YY YY YY YY YY
1237.6 209.0

Annotations:

^{2,5}A_{GlcNAc}Y ^{2,5}A_{GlcNAc}Y ^{2,5}A_{GlcNAc}Y ^{2,5}A_{Man}Y ^{2,5}A_{Man}Y ^{2,5}A_{Man}Y
1272.4 272.0
1277.5 143.0

Annotations:

BZ BZ BZ
1336.5 339.0

Annotations:

BY BY BY CZ CZ CZ
1337.6 316.0

Annotations:

^{2,4}A_{GlcNAc}Z ^{2,4}A_{GlcNAc}Z ^{2,4}A_{GlcNAc}Z
1338.6 108.0
1355.2 103.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y
1355.4 100.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y
1355.6 156.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y
1357.4 155.0
1396.3 102.0
1397.5 408.0

Annotations:

Y
1397.8 153.0

Annotations:

Y
1398.7 197.0
1399.7 285.0

Annotations:

^{2,5}A_{GlcNAc}Y ^{2,5}A_{GlcNAc}Y ^{2,5}A_{GlcNAc}Y ^{2,5}A_{Man}
1499.6 408.0
1500.6 113.0
1517.7 459.0

Annotations:

^{2,4}A_{GlcNAc}
1541.6 356.0

Annotations:

Z Z Z
1542.6 176.0
1559.5 308.0

Annotations:

Y Y Y
1559.7 206.0

Annotations:

Y Y Y
1560.6 134.0
1561.4 158.0

Annotations:

^{2,5}A_{GlcNAc}
1562.7 161.0
1660.8 211.0

Annotations:

B
1661.8 122.0
1680.5 255.0
1684.3 104.0
1686.5 153.0
1722.8 132.0

There are 7 similar spectra:

Id Structure Score

429

0.89

590

0.89

2236

0.89

565

0.88

2330

0.80

2329

0.78

2328

0.70
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