Cystic fibrosis and bacterial colonization define the sputum N-glycosylation phenotype

PubMed Entry

GlyToucan Accession Number: G62446JD

Peak Intensity
246.0 3253.0
262.1 5757.0

Annotations:

BY CZ BY CZ
290.0 542.0

Annotations:

B
303.4 1786.0
304.1 2262.0

Annotations:

B^{0,4}X_{Gal} B^{2,4}X_{GlcNAc} B^{0,4}X_{GlcNAc} B^{2,4}X_{GlcNAc}
308.0 597.0

Annotations:

C
382.8 1919.0
424.0 4443.0

Annotations:

C^{0,2}X_{Gal} ^{2,5}X_{GlcNAc}Y Y^{2,5}X_{GlcNAc} ^{1,5}A_{Gal} C^{1,3}X_{Man} ^{1,3}A_{Man}Y C^{2,4}X_{GlcNAc} ^{0,2}A_{Man}Y ^{0,4}A_{Man} ^{1,3}A_{Man}Y ^{2,4}A_{Man}Y
449.2 1345.0
470.1 1528.0

Annotations:

C
490.3 2134.0

Annotations:

C^{1,4}X_{GlcNAc} ^{0,3}A_{GlcNAc}Y C^{0,3}X_{Gal}
494.2 872.0

Annotations:

B^{2,5}X_{GlcNAc}
509.3 1223.0

Annotations:

B^{3,5}X_{GlcNAc}
519.3 5913.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{3,5}X_{Gal}Y ^{3,5}X_{GlcNAc}Y Y^{3,5}X_{GlcNAc}
527.3 1893.0
552.0 473.0
570.3 1332.0

Annotations:

BY CZ
597.8 7447.0

Annotations:

B^{0,4}X_{Gal} ^{0,3}X_{NeuAc}Z B^{1,5}X_{NeuAc} ^{0,3}A_{GlcNAc}Z ^{3,5}A_{GlcNAc}Z B^{1,4}X_{Man} ^{1,4}A_{Man}Z Y^{0,2}X_{GlcNAc} ^{0,2}X_{GlcNAc}
600.2 8529.0

Annotations:

CY
600.7 10292.0

Annotations:

^{3,5}A_{GlcNAc}Y ^{3,5}X_{Gal}Y
601.2 10339.0

Annotations:

^{3,5}X_{Gal}Y
601.8 2217.0
602.1 427.0
639.1 3602.0

Annotations:

^{1,4}A_{GlcNAc}Z
651.3 12434.0

Annotations:

Y^{1,5}X_{GlcNAc} ^{2,4}X_{NeuAc}Y
655.3 13802.0

Annotations:

B
656.1 1673.0
656.3 3794.0
657.3 1456.0

Annotations:

^{1,4}A_{GlcNAc}Y ^{1,5}A_{GlcNAc}Y ^{1,5}A_{Man}
673.3 654.0

Annotations:

C
682.0 708.0
682.9 3503.0

Annotations:

^{1,5}A_{GlcNAc}Z
692.8 416.0

Annotations:

Z
697.0 2196.0

Annotations:

B^{0,4}X_{NeuAc}
701.8 48693.0

Annotations:

Y
702.2 28765.0

Annotations:

Y
702.7 15341.0

Annotations:

Y
703.1 4471.0
703.3 3561.0
708.6 880.0

Annotations:

^{3,5}A_{GlcNAc}
723.2 2964.0

Annotations:

B^{1,3}X_{GlcNAc} B^{2,4}X_{NeuAc} ^{0,4}X_{NeuAc}Y
732.3 762.0

Annotations:

^{2,4}X_{NeuAc}Y
733.5 3916.0
733.8 7723.0

Annotations:

C^{1,5}X_{GlcNAc} C^{2,4}X_{NeuAc}
743.3 2413.0

Annotations:

B^{0,4}X_{GlcNAc} B^{2,4}X_{GlcNAc}
748.4 1168.0

Annotations:

^{2,4}A_{GlcNAc}Y
750.4 352.0
753.3 2222.0

Annotations:

^{1,3}X_{Man}
754.3 3924.0
762.7 769.0

Annotations:

^{3,5}A_{GlcNAc}Y
765.4 1999.0
773.2 3107.0

Annotations:

B
773.5 3974.0

Annotations:

B
775.5 1017.0

Annotations:

C^{1,5}X_{Man} ^{1,5}X_{NeuAc}
781.8 2311.0

Annotations:

C
783.4 8478.0

Annotations:

Y
783.8 11112.0
784.2 2522.0
803.9 1553.0
804.2 773.0
804.8 2572.0

Annotations:

C^{2,5}X_{GlcNAc}
816.6 3863.0
817.1 8819.0

Annotations:

B
817.4 20920.0

Annotations:

B
818.3 8995.0
824.2 2506.0
824.8 15415.0

Annotations:

^{0,2}X_{GlcNAc} ^{0,4}X_{NeuAc}
825.3 541.0
833.8 6634.0

Annotations:

Z^{1,3}X_{Man} ^{1,3}X_{Man}Z Z^{1,3}X_{GlcNAc} ^{2,5}A_{Man}Y ^{1,3}X_{GlcNAc} ^{2,4}X_{NeuAc}
834.3 4464.0

Annotations:

^{1,3}X_{GlcNAc} ^{2,4}X_{NeuAc}
834.5 2720.0

Annotations:

^{1,3}X_{GlcNAc} ^{2,4}X_{NeuAc}
834.9 5003.0

Annotations:

C
835.3 61287.0

Annotations:

C
836.0 2388.0
836.3 15681.0
837.3 8916.0
837.6 2410.0
838.5 1504.0
839.4 1802.0

Annotations:

^{0,3}X_{GlcNAc}
845.8 2347.0

Annotations:

^{1,5}A_{Man}Z ^{1,5}A_{GlcNAc}Z
854.4 476.0

Annotations:

^{0,4}X_{GlcNAc} ^{2,4}X_{GlcNAc}
855.0 8351.0

Annotations:

^{0,4}X_{GlcNAc} ^{2,4}X_{GlcNAc}
855.4 5086.0
855.7 1856.0
856.3 1840.0
863.6 1511.0

Annotations:

^{1,5}A_{GlcNAc}Y ^{1,5}A_{Man}Y
864.3 414.0
864.8 6670.0
877.5 2010.0

Annotations:

^{1,3}A_{Man} ^{2,4}A_{Man}
878.5 1873.0

Annotations:

^{3,5}X_{GlcNAc}Y Y^{3,5}X_{GlcNAc}
907.3 3779.0

Annotations:

^{1,4}A_{Man}
908.2 682.0
934.5 1044.0

Annotations:

Z
944.0 1673.0
1003.4 9846.0
1004.1 2167.0

Annotations:

B^{0,3}X_{GlcNAc} ^{1,4}A_{GlcNAc}Z
1004.4 2024.0

Annotations:

B^{0,3}X_{GlcNAc} ^{1,4}A_{GlcNAc}Z
1026.2 1837.0
1039.5 4279.0

Annotations:

^{2,4}A_{GlcNAc}Y
1098.2 1823.0
1114.4 1627.0

Annotations:

Y
1114.6 2812.0

Annotations:

Y
1184.5 2451.0

Annotations:

^{1,4}A_{GlcNAc}Y C^{0,3}X_{Gal} ^{0,2}X_{NeuAc}Y ^{3,5}X_{Gal}Z
1203.6 3751.0
1222.3 1293.0
1225.3 372.0

Annotations:

Z^{3,5}X_{GlcNAc}
1257.5 740.0

Annotations:

Y^{0,4}X_{GlcNAc} Y^{2,4}X_{GlcNAc} ^{2,4}X_{GlcNAc}
1317.7 374.0

Annotations:

Y
1320.3 2127.0
1321.5 1572.0
1327.3 902.0
1345.5 3851.0

Annotations:

^{1,5}X_{Gal}
1346.6 6052.0

Annotations:

C^{1,5}X_{NeuAc} ^{0,2}X_{NeuAc}Y
1359.6 965.0

Annotations:

Y^{0,2}X_{GlcNAc} ^{0,2}X_{Gal}
1362.5 12705.0

Annotations:

C
1363.0 5577.0
1363.4 11397.0
1364.3 431.0
1364.6 5780.0
1365.6 2005.0
1404.5 3654.0

Annotations:

^{2,4}A_{GlcNAc}
1405.5 589.0

Annotations:

Y
1423.4 756.0
1425.7 839.0
1446.7 1898.0

Annotations:

B^{1,3}X_{GlcNAc} B^{2,4}X_{NeuAc}
1464.8 1983.0

Annotations:

C^{1,3}X_{GlcNAc} C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc}
1465.6 3218.0
1468.6 2369.0
1479.7 1955.0

Annotations:

Y
1489.7 888.0
1507.5 5027.0

Annotations:

^{1,3}X_{Man}
1521.6 921.0

Annotations:

C^{1,3}X_{NeuAc}
1547.6 7290.0

Annotations:

B
1548.5 2435.0
1549.4 5055.0

Annotations:

Z
1550.6 2984.0
1565.4 1950.0

Annotations:

C
1565.6 2155.0

Annotations:

C
1566.7 6109.0
1567.7 2306.0

Annotations:

Y
1568.6 1327.0

There are 2 similar spectra:

Id Structure Score

2511

0.55

424

0.55
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