Cystic fibrosis and bacterial colonization define the sputum N-glycosylation phenotype

PubMed Entry

GlyToucan Accession Number: G17856XT

Peak Intensity
290.2 153.0

Annotations:

B
304.1 268.0

Annotations:

B^{0,4}X_{GlcNAc} B^{2,4}X_{GlcNAc} B^{0,4}X_{Gal} ^{2,4}A_{Man}Z B^{2,4}X_{GlcNAc}
364.2 110.0

Annotations:

B
392.1 217.0

Annotations:

^{3,5}A_{GlcNAc}Z B^{1,5}X_{Gal}
407.1 137.0

Annotations:

Z
410.2 173.0

Annotations:

^{0,2}A_{Gal} C^{1,5}X_{Gal}
424.1 191.0

Annotations:

^{1,5}A_{Gal} ^{0,2}A_{GlcNAc}Y ^{1,3}A_{Man}Y C^{1,3}X_{Man} ^{0,2}A_{Man}Y ^{0,4}A_{Man} ^{1,3}A_{Man}Y ^{2,4}A_{Man}Y C^{0,2}X_{Gal}
425.2 172.0

Annotations:

Y
452.3 182.0

Annotations:

B
470.2 576.0

Annotations:

C
480.2 122.0

Annotations:

B^{3,5}X_{NeuAc} ^{1,5}A_{Man}Z ^{1,5}X_{GlcNAc}Z Z^{1,5}X_{Man} ^{1,5}X_{Man}Z ^{1,5}X_{Man}Z Z^{1,5}X_{GlcNAc} Z^{1,5}X_{GlcNAc}
490.2 334.0

Annotations:

^{0,3}A_{GlcNAc}Y C^{1,4}X_{GlcNAc}
507.5 102.0
508.2 989.0

Annotations:

BZ
509.2 101.0

Annotations:

B^{3,5}X_{GlcNAc}
519.2 162.0
533.4 182.0
550.0 104.0
550.3 168.0
573.3 143.0
591.3 231.0

Annotations:

C^{0,3}X_{Gal} Y^{1,5}X_{Man} ^{1,5}X_{Man} ^{1,5}X_{Gal}Y ^{0,3}A_{GlcNAc}Y C^{1,4}X_{GlcNAc}
600.3 260.0
600.8 192.0
601.3 126.0
620.8 161.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{3,5}X_{Gal}Y ^{3,5}X_{GlcNAc}Y ^{3,5}X_{GlcNAc}Y Y^{3,5}X_{GlcNAc} Y^{3,5}X_{GlcNAc}
622.1 175.0
630.2 111.0

Annotations:

C^{2,5}X_{NeuAc}
641.9 109.0

Annotations:

^{0,2}A_{GlcNAc}Z B^{1,3}X_{Man} ^{0,2}A_{Man}Z B^{3,5}X_{NeuAc}
651.4 115.0
652.4 116.0
655.3 3422.0

Annotations:

B
656.3 1037.0

Annotations:

^{1,4}A_{GlcNAc}Y
657.4 244.0

Annotations:

CY
671.7 164.0

Annotations:

BY BY CZ CZ
672.3 150.0

Annotations:

Y^{1,5}X_{Man} Y^{1,5}X_{GlcNAc} ^{1,5}X_{Gal}Y ^{1,5}X_{Gal}Y Y^{1,5}X_{GlcNAc} ^{1,5}X_{GlcNAc} C^{1,5}X_{NeuAc} ^{0,3}A_{GlcNAc}Y
672.8 123.0

Annotations:

C
673.2 366.0

Annotations:

C
674.2 193.0
692.8 208.0

Annotations:

YZ ZY
693.3 144.0

Annotations:

YZ ZY
701.8 2645.0

Annotations:

YY
702.3 1944.0

Annotations:

YY
702.8 1100.0
703.3 527.0
708.8 112.0

Annotations:

Y^{1,3}X_{Man} ^{3,5}A_{GlcNAc}Y ^{3,5}A_{GlcNAc}Y ^{0,4}X_{Gal}Y ^{0,4}X_{Gal}Y Y^{1,3}X_{GlcNAc} Y^{1,3}X_{GlcNAc}
715.4 164.0

Annotations:

^{1,3}A_{Man} C^{0,4}X_{NeuAc} C^{1,5}X_{Man} ^{1,5}A_{GlcNAc}Y B^{1,4}X_{NeuAc}
716.3 139.0

Annotations:

B^{2,4}X_{NeuAc} ^{1,5}X_{GlcNAc}Y Y^{1,5}X_{Man} ^{3,5}X_{NeuAc}Y ^{0,3}A_{GlcNAc}Y ^{0,3}A_{GlcNAc}Y C^{1,4}X_{GlcNAc} C^{1,4}X_{GlcNAc}
731.3 166.0

Annotations:

^{0,2}A_{GlcNAc}Y ^{0,2}A_{GlcNAc}Y C^{1,3}X_{GlcNAc} C^{1,3}X_{GlcNAc} C^{2,4}X_{NeuAc}
743.3 127.0

Annotations:

B^{1,3}X_{Man} B^{0,4}X_{GlcNAc} B^{2,4}X_{GlcNAc} B^{0,4}X_{GlcNAc} B^{2,4}X_{GlcNAc} ^{0,2}X_{GlcNAc}Y ^{0,4}X_{NeuAc}Y
744.4 198.0

Annotations:

Z^{1,5}X_{GlcNAc} Z^{1,5}X_{GlcNAc} ^{2,5}A_{Man} ^{1,3}X_{GlcNAc}Z Z^{1,3}X_{Man} ^{2,4}X_{NeuAc}Z
753.4 265.0

Annotations:

^{1,3}X_{GlcNAc}Y Y^{1,3}X_{Man} ^{2,4}X_{NeuAc}Y Y^{1,5}X_{GlcNAc} Y^{1,5}X_{GlcNAc}
753.7 112.0

Annotations:

^{1,3}X_{GlcNAc}Y Y^{1,3}X_{Man} ^{2,4}X_{NeuAc}Y Y^{1,5}X_{GlcNAc} Y^{1,5}X_{GlcNAc}
754.0 112.0

Annotations:

ZZ
754.3 226.0

Annotations:

ZZ
771.6 114.0

Annotations:

^{2,4}A_{GlcNAc}Z ^{2,4}A_{Man}Z Z^{0,2}X_{GlcNAc} Z^{0,2}X_{GlcNAc}
773.3 737.0

Annotations:

B
773.7 277.0

Annotations:

B
774.3 401.0

Annotations:

YZ ZY
782.4 242.0

Annotations:

C
782.8 305.0

Annotations:

YY
783.2 153.0

Annotations:

YY
783.4 136.0

Annotations:

YY
783.7 116.0

Annotations:

YY
783.9 114.0
784.3 208.0
784.8 101.0

Annotations:

^{3,5}A_{GlcNAc}Z
789.3 144.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{2,4}A_{Man}Y ^{1,5}A_{Man} ^{0,3}X_{NeuAc}Y ^{0,3}X_{NeuAc}Y
789.9 120.0

Annotations:

YY
794.4 541.0

Annotations:

Z
794.7 204.0

Annotations:

Z
795.0 131.0

Annotations:

Z
803.3 12436.0

Annotations:

Y
803.8 8710.0

Annotations:

Y
804.3 4127.0
804.8 1003.0
805.4 202.0
817.3 3585.0

Annotations:

B
818.3 1601.0

Annotations:

^{0,3}A_{GlcNAc} C^{1,4}X_{GlcNAc} C^{1,4}X_{GlcNAc} ^{1,4}X_{NeuAc}Z ^{1,4}X_{NeuAc}Z ^{1,5}X_{Man}Y Y^{1,5}X_{Man}
819.2 694.0

Annotations:

^{0,3}A_{GlcNAc}Y C^{1,4}X_{Man} ^{1,4}A_{Man}Y ^{1,4}X_{GlcNAc}Y Y^{1,4}X_{GlcNAc}
824.4 134.0

Annotations:

B^{1,3}X_{GlcNAc} B^{1,3}X_{GlcNAc} B^{2,4}X_{NeuAc} ^{0,2}X_{GlcNAc}Y Y^{0,2}X_{GlcNAc} ^{0,4}X_{NeuAc}Y ^{0,4}X_{NeuAc}Y
824.9 215.0

Annotations:

^{0,2}X_{GlcNAc}Y Y^{0,2}X_{GlcNAc} ^{0,4}X_{NeuAc}Y ^{0,4}X_{NeuAc}Y ^{2,5}A_{GlcNAc} ^{1,3}X_{GlcNAc}Z Z^{1,3}X_{GlcNAc} ^{2,4}X_{NeuAc}Z ^{2,4}X_{NeuAc}Z
825.4 128.0

Annotations:

^{2,5}A_{GlcNAc} ^{1,3}X_{GlcNAc}Z Z^{1,3}X_{GlcNAc} ^{2,4}X_{NeuAc}Z ^{2,4}X_{NeuAc}Z
833.9 370.0

Annotations:

^{1,3}X_{GlcNAc}Y Y^{1,3}X_{GlcNAc} ^{2,4}X_{NeuAc}Y ^{2,4}X_{NeuAc}Y
834.4 265.0

Annotations:

^{1,3}X_{GlcNAc}Y Y^{1,3}X_{GlcNAc} ^{2,4}X_{NeuAc}Y ^{2,4}X_{NeuAc}Y
835.3 8000.0

Annotations:

C
836.4 2792.0
837.4 1308.0

Annotations:

B^{3,5}X_{GlcNAc} B^{3,5}X_{GlcNAc}
838.3 317.0

Annotations:

^{1,4}A_{GlcNAc} C^{0,3}X_{GlcNAc} C^{0,3}X_{GlcNAc} ^{3,5}X_{GlcNAc}Z Z^{3,5}X_{GlcNAc}
844.8 105.0

Annotations:

^{1,4}X_{Man}Z Z^{1,4}X_{Man} B^{0,4}X_{GlcNAc} B^{2,4}X_{GlcNAc} B^{0,4}X_{GlcNAc} B^{2,4}X_{GlcNAc}
845.7 120.0

Annotations:

^{1,5}A_{Man}Z ^{0,4}X_{GlcNAc}Z ^{2,4}X_{GlcNAc}Z Z^{0,4}X_{GlcNAc} Z^{2,4}X_{GlcNAc}
846.3 136.0

Annotations:

^{0,4}X_{GlcNAc}Z ^{2,4}X_{GlcNAc}Z Z^{0,4}X_{GlcNAc} Z^{2,4}X_{GlcNAc} C^{3,5}X_{GlcNAc} C^{3,5}X_{GlcNAc}
854.4 373.0

Annotations:

^{1,3}X_{Man} ^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y Y^{0,4}X_{GlcNAc} Y^{2,4}X_{GlcNAc}
854.8 652.0

Annotations:

^{1,3}X_{Man} ^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y Y^{0,4}X_{GlcNAc} Y^{2,4}X_{GlcNAc}
855.3 654.0

Annotations:

^{1,3}X_{Man} ^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y Y^{0,4}X_{GlcNAc} Y^{2,4}X_{GlcNAc}
855.8 277.0
856.8 112.0
863.8 253.0

Annotations:

^{1,5}A_{Man}Y
864.3 444.0
864.8 142.0
865.3 186.0
865.6 140.0
866.2 149.0
874.9 793.0

Annotations:

B
875.3 787.0

Annotations:

B
875.8 759.0

Annotations:

Z Z
876.3 246.0

Annotations:

Z Z
876.8 295.0

Annotations:

^{1,5}X_{NeuAc} ^{1,3}A_{Man}
877.4 345.0

Annotations:

^{1,3}A_{Man}
878.1 120.0
884.3 608.0

Annotations:

C
884.9 3886.0

Annotations:

Y Y
885.4 2156.0
885.9 742.0

Annotations:

^{1,5}A_{GlcNAc}Z
886.4 462.0

Annotations:

^{1,5}A_{GlcNAc}Z
886.8 124.0

Annotations:

^{1,5}A_{GlcNAc}Z
891.6 106.0

Annotations:

BY CZ
898.9 119.0

Annotations:

^{1,5}X_{GlcNAc} ^{1,5}X_{GlcNAc} ^{3,5}X_{NeuAc}
914.3 134.0

Annotations:

BZ
915.4 125.0
923.4 194.0
926.0 123.0

Annotations:

^{0,2}X_{GlcNAc} ^{0,2}X_{GlcNAc} ^{0,4}X_{NeuAc}
926.4 1499.0

Annotations:

^{0,2}X_{GlcNAc} ^{0,2}X_{GlcNAc} ^{0,4}X_{NeuAc}
926.9 653.0
927.4 153.0
927.8 142.0
932.6 148.0

Annotations:

BY CZ
933.4 175.0

Annotations:

^{2,4}A_{GlcNAc}Z
934.5 100.0

Annotations:

YZ ZY YZ YZ ZY ZY
935.3 592.0
935.8 398.0

Annotations:

^{1,3}X_{GlcNAc} ^{1,3}X_{GlcNAc} ^{2,4}X_{NeuAc}
936.3 342.0

Annotations:

^{1,3}X_{GlcNAc} ^{1,3}X_{GlcNAc} ^{2,4}X_{NeuAc}
936.6 163.0
936.9 203.0

Annotations:

C^{1,5}X_{GlcNAc}
937.4 143.0

Annotations:

C^{1,5}X_{GlcNAc}
943.3 660.0
943.4 653.0
944.4 299.0
950.3 135.0

Annotations:

CY
951.1 150.0

Annotations:

^{2,4}A_{GlcNAc}Y
951.5 152.0

Annotations:

^{2,4}A_{GlcNAc}Y
952.2 128.0

Annotations:

YY YY YY
952.5 102.0

Annotations:

YY YY YY
956.0 198.0

Annotations:

^{0,4}X_{GlcNAc} ^{2,4}X_{GlcNAc} ^{0,4}X_{GlcNAc} ^{2,4}X_{GlcNAc}
956.4 2032.0

Annotations:

^{0,4}X_{GlcNAc} ^{2,4}X_{GlcNAc} ^{0,4}X_{GlcNAc} ^{2,4}X_{GlcNAc}
956.9 1662.0
957.4 1001.0
957.8 142.0
958.1 134.0
958.6 157.0
961.4 2586.0
962.4 1097.0

Annotations:

^{1,5}X_{GlcNAc}Z Z^{1,5}X_{Man} ^{1,5}X_{Man}Z ^{1,5}X_{Man}Z Z^{1,5}X_{GlcNAc} Z^{1,5}X_{GlcNAc}
963.4 544.0

Annotations:

^{0,3}A_{GlcNAc}Z B^{1,4}X_{GlcNAc}
965.3 548.0

Annotations:

^{3,5}A_{GlcNAc}Y
965.9 312.0
966.4 419.0
966.9 154.0
967.9 145.0
968.3 104.0
968.8 163.0
976.9 249.0

Annotations:

^{2,5}A_{GlcNAc}Z
977.4 184.0

Annotations:

^{2,5}A_{GlcNAc}Z
977.9 168.0

Annotations:

C^{1,5}X_{Man}
978.3 142.0

Annotations:

C^{1,5}X_{Man}
979.4 231.0
980.6 126.0

Annotations:

^{1,5}X_{GlcNAc}Y Y^{1,5}X_{Man} ^{1,5}X_{Man}Y ^{1,5}X_{Man}Y Y^{1,5}X_{GlcNAc} Y^{1,5}X_{GlcNAc}
1003.3 115.0
1077.4 167.0

Annotations:

Z^{2,4}X_{GlcNAc} Z^{0,4}X_{GlcNAc} ^{2,4}X_{GlcNAc}Z Z^{0,4}X_{GlcNAc} Z^{2,4}X_{GlcNAc}
1095.4 122.0

Annotations:

^{2,4}X_{GlcNAc}Y Y^{0,4}X_{GlcNAc} Y^{2,4}X_{GlcNAc} Y^{0,4}X_{GlcNAc} Y^{2,4}X_{GlcNAc}
1113.5 227.0
1114.5 189.0

Annotations:

YY YY
1136.5 169.0

Annotations:

^{2,4}A_{GlcNAc}Z B^{0,2}X_{Gal}
1137.5 262.0

Annotations:

Z
1139.3 128.0
1141.5 104.0
1154.6 161.0

Annotations:

^{2,4}A_{GlcNAc}Y C^{0,2}X_{Gal}
1155.5 311.0

Annotations:

Y
1157.5 158.0
1184.4 191.0

Annotations:

^{0,3}A_{GlcNAc}Y C^{1,4}X_{GlcNAc} C^{0,3}X_{Gal}
1202.3 124.0
1224.5 759.0

Annotations:

^{2,4}A_{GlcNAc}Z
1225.4 315.0

Annotations:

^{1,4}A_{GlcNAc}Y C^{0,3}X_{GlcNAc} ^{3,5}X_{Gal}Z ^{3,5}X_{GlcNAc}Z ^{3,5}X_{GlcNAc}Z Z^{3,5}X_{GlcNAc} Z^{3,5}X_{GlcNAc}
1257.5 116.0

Annotations:

^{1,3}X_{Man} ^{0,4}X_{Gal}Y Y^{1,3}X_{Man} ^{2,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y Y^{0,4}X_{GlcNAc} Y^{2,4}X_{GlcNAc} Y^{0,4}X_{GlcNAc} Y^{2,4}X_{GlcNAc}
1299.5 114.0

Annotations:

Z
1303.5 159.0
1316.5 199.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{1,5}A_{Man}Y
1317.5 463.0

Annotations:

Y
1318.7 154.0
1321.6 101.0
1324.5 144.0
1326.5 300.0

Annotations:

BZ BZ
1327.3 160.0

Annotations:

Z^{1,5}X_{Man} ^{1,5}X_{Gal}Z ^{1,5}X_{Gal}Z Z^{1,5}X_{GlcNAc} Z^{1,5}X_{GlcNAc}
1327.5 188.0

Annotations:

Z^{1,5}X_{Man} ^{1,5}X_{Gal}Z ^{1,5}X_{Gal}Z Z^{1,5}X_{GlcNAc} Z^{1,5}X_{GlcNAc}
1343.5 112.0

Annotations:

C^{1,5}X_{Gal}
1344.5 635.0

Annotations:

BY BY CZ CZ
1345.5 590.0

Annotations:

Y^{1,5}X_{Man} Y^{1,5}X_{GlcNAc} ^{1,5}X_{Gal}Y ^{1,5}X_{Gal}Y Y^{1,5}X_{GlcNAc} ^{1,5}X_{GlcNAc}
1362.3 202.0

Annotations:

CY CY
1362.6 286.0

Annotations:

CY CY
1363.3 262.0
1363.7 315.0
1367.5 112.0

Annotations:

BZ
1368.4 140.0
1368.7 119.0
1369.3 102.0

Annotations:

ZZ
1369.5 145.0

Annotations:

ZZ
1370.6 285.0
1386.5 811.0

Annotations:

^{2,4}A_{GlcNAc}Z ^{2,4}A_{GlcNAc}Z
1387.6 457.0

Annotations:

YZ ZY
1388.6 220.0
1404.2 157.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y
1404.5 331.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y
1405.6 218.0

Annotations:

YY
1489.6 123.0

Annotations:

^{2,5}A_{Man} ^{1,3}X_{GlcNAc}Z Z^{1,3}X_{Man} ^{2,4}X_{NeuAc}Z Z^{1,5}X_{GlcNAc} Z^{1,5}X_{GlcNAc}
1502.5 115.0

Annotations:

Z
1503.7 107.0

Annotations:

B^{1,3}X_{NeuAc}
1505.7 113.0

Annotations:

C^{1,3}X_{Man} C^{0,4}X_{GlcNAc} C^{2,4}X_{GlcNAc} C^{0,4}X_{GlcNAc} C^{2,4}X_{GlcNAc} ^{0,2}A_{Man}
1507.3 169.0

Annotations:

^{1,3}X_{GlcNAc}Y Y^{1,3}X_{Man} ^{2,4}X_{NeuAc}Y Y^{1,5}X_{GlcNAc} Y^{1,5}X_{GlcNAc}
1523.6 220.0
1529.6 138.0

Annotations:

BZ BZ
1530.5 216.0

Annotations:

^{0,4}X_{GlcNAc}Z ^{2,4}X_{GlcNAc}Z
1531.7 100.0

Annotations:

ZZ
1547.7 796.0

Annotations:

B
1548.5 686.0

Annotations:

^{0,4}X_{GlcNAc}Y ^{2,4}X_{GlcNAc}Y ^{1,5}X_{Gal}
1549.7 356.0

Annotations:

YZ ZY
1550.6 246.0
1565.6 4292.0

Annotations:

C
1566.6 2553.0
1567.5 974.0

Annotations:

YY
1567.7 919.0

Annotations:

YY
1568.6 388.0
1590.6 361.0

Annotations:

Z
1591.7 160.0
1591.8 168.0
1592.4 148.0

Annotations:

Y^{0,3}X_{GlcNAc} Y^{0,3}X_{GlcNAc} ^{0,3}X_{Gal}
1592.8 221.0

Annotations:

Y^{0,3}X_{GlcNAc} Y^{0,3}X_{GlcNAc} ^{0,3}X_{Gal}
1607.6 196.0

Annotations:

^{2,4}A_{GlcNAc}
1608.5 223.0

Annotations:

Y
1609.6 126.0
1609.8 114.0
1632.5 135.0

Annotations:

^{0,2}X_{GlcNAc}Z ^{0,4}X_{NeuAc}Z ^{0,4}X_{NeuAc}Z Z^{0,2}X_{GlcNAc}
1649.5 137.0

Annotations:

B^{1,3}X_{GlcNAc} B^{1,3}X_{GlcNAc} B^{2,4}X_{NeuAc}
1667.7 172.0

Annotations:

C^{1,3}X_{GlcNAc} C^{1,3}X_{GlcNAc} C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc}
1668.7 229.0
1682.6 251.0

Annotations:

Y
1683.7 252.0
1684.8 103.0
1694.8 106.0

Annotations:

C^{3,5}X_{GlcNAc} C^{3,5}X_{GlcNAc}
1708.6 133.0

Annotations:

C^{0,4}X_{GlcNAc} C^{2,4}X_{GlcNAc} C^{0,4}X_{GlcNAc} C^{2,4}X_{GlcNAc} ^{1,3}X_{NeuAc}Z ^{1,3}X_{NeuAc}Z
1709.7 162.0
1711.6 145.0
1714.4 110.0
1750.7 1078.0

Annotations:

B
1751.7 1114.0
1752.7 801.0

Annotations:

Z Z
1753.6 249.0
1768.8 242.0

Annotations:

C
1769.7 192.0
1772.6 146.0

There are 1 similar spectra:

Id Structure Score

2210

0.72
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