In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.

PubMed Entry

GlyToucan Accession Number: G79446WY

Peak Intensity
263.1 259.0

Annotations:

^{0,2}A_{GlcNAc}Z
290.0 130.0

Annotations:

B
382.1 333.0

Annotations:

C
424.2 367.0

Annotations:

^{1,5}A_{Gal} ^{1,3}A_{Man} ^{1,3}A_{Man}Y ^{0,4}A_{Man}Y ^{1,3}A_{Man}Y ^{2,4}A_{Man}Y C^{0,2}X_{Gal} C^{0,2}X_{Gal} BY CZ
434.1 192.0

Annotations:

CY B^{0,2}X_{NeuAc}
463.3 291.0
506.0 146.0
540.3 136.0

Annotations:

B^{1,4}X_{NeuAc} B^{1,5}X_{GlcNAc} B^{1,5}X_{Gal} ^{0,2}A_{GlcNAc}Z B^{1,3}X_{Man} ^{0,2}A_{Man}Z
616.3 207.0

Annotations:

C^{1,5}X_{NeuAc} CY ^{0,3}A_{Man} ^{1,4}A_{Man}Y
628.2 123.0

Annotations:

BY CZ ^{2,4}A_{GlcNAc}Z Y^{2,4}X_{GlcNAc} ^{2,4}X_{GlcNAc}Y
653.2 168.0
655.2 380.0

Annotations:

B
656.1 142.0
658.3 250.0

Annotations:

^{0,2}A_{GlcNAc}Z YY
670.2 228.0

Annotations:

BZ Z^{0,2}X_{Gal} Z^{0,2}X_{GlcNAc} ^{0,2}X_{Gal}Z
687.9 226.0

Annotations:

C^{0,4}X_{Gal} ^{0,3}X_{NeuAc}Y BY CZ
703.2 101.0
710.8 109.0

Annotations:

C^{2,4}X_{NeuAc}
734.3 128.0

Annotations:

C^{1,5}X_{Man} C^{2,4}X_{NeuAc}
752.8 483.0

Annotations:

B
753.2 411.0

Annotations:

B
761.7 182.0

Annotations:

C
774.3 315.0

Annotations:

Z
782.8 1967.0

Annotations:

Y
783.2 2122.0

Annotations:

Y
783.8 957.0
784.3 490.0
784.7 447.0
785.3 242.0
789.1 329.0

Annotations:

^{1,5}A_{Man} ^{0,3}X_{NeuAc}Y
791.3 160.0

Annotations:

C^{1,3}X_{NeuAc}
803.8 197.0

Annotations:

B^{2,4}X_{NeuAc} ^{1,5}A_{Man}Z
805.3 122.0

Annotations:

C^{1,4}X_{NeuAc}
817.3 745.0

Annotations:

B
818.3 770.0

Annotations:

^{1,4}A_{GlcNAc} C^{0,3}X_{Gal} C^{1,4}X_{Gal} ^{1,4}X_{NeuAc}Z
819.4 316.0

Annotations:

^{1,4}A_{GlcNAc}Y ^{1,4}X_{GlcNAc}
820.5 152.0

Annotations:

Y
825.3 227.0

Annotations:

^{2,4}X_{NeuAc}Z
835.3 1744.0

Annotations:

C
836.1 759.0
836.5 500.0
837.3 306.0
846.3 221.0
846.8 105.0
854.9 336.0

Annotations:

^{2,4}X_{GlcNAc} ^{0,2}X_{NeuAc}
855.3 508.0

Annotations:

^{2,4}X_{GlcNAc} ^{0,2}X_{NeuAc}
855.8 167.0

Annotations:

^{1,5}X_{NeuAc}
856.0 208.0

Annotations:

^{1,5}X_{NeuAc}
856.3 186.0

Annotations:

^{1,5}X_{NeuAc}
858.6 154.0
866.3 201.0
875.8 703.0

Annotations:

Z
876.5 334.0
877.2 180.0

Annotations:

^{1,3}A_{Man} ^{2,4}A_{Man}
884.8 331.0

Annotations:

Y
885.7 167.0
885.9 397.0
886.3 122.0
896.1 276.0

Annotations:

C^{1,5}X_{GlcNAc}
905.3 220.0
906.0 159.0

Annotations:

^{0,2}X_{Gal} ^{0,4}X_{NeuAc} ^{3,5}A_{GlcNAc}Z
914.8 481.0
915.3 739.0

Annotations:

^{2,4}X_{NeuAc}
915.9 284.0

Annotations:

ZZ ZZ
927.3 144.0
935.5 289.0

Annotations:

^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal}
935.8 1754.0

Annotations:

^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal}
936.3 1268.0

Annotations:

^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{2,5}A_{GlcNAc}Z
936.7 475.0

Annotations:

^{2,5}A_{GlcNAc}Z
936.9 607.0

Annotations:

C^{1,5}X_{Man}
944.8 637.0
945.5 531.0
945.8 102.0
955.8 440.0
956.5 219.0
957.3 174.0
1114.4 493.0

Annotations:

Y
1161.4 158.0
1201.5 109.0

Annotations:

^{2,4}A_{GlcNAc}Y
1203.4 181.0
1260.5 117.0
1276.5 143.0

Annotations:

Y
1276.6 170.0

Annotations:

Y
1277.5 260.0
1281.5 287.0

Annotations:

ZZ
1362.5 236.0

Annotations:

CY C^{3,5}X_{Gal} CY ^{2,5}X_{NeuAc}Y
1368.5 121.0
1386.5 249.0

Annotations:

^{2,4}A_{GlcNAc}Z B^{0,2}X_{Gal} B^{0,4}X_{NeuAc}
1404.5 140.0

Annotations:

^{2,4}A_{GlcNAc}Y C^{0,2}X_{Gal} C^{0,4}X_{NeuAc}
1405.4 123.0

Annotations:

Y
1406.5 137.0
1422.5 406.0
1423.3 108.0

Annotations:

C^{2,4}X_{NeuAc}
1425.5 171.0
1463.6 254.0
1480.5 255.0

Annotations:

C^{1,3}X_{NeuAc}
1481.7 119.0
1482.6 130.0
1524.6 210.0

Annotations:

C
1525.6 299.0
1526.7 257.0
1547.4 101.0

Annotations:

BY CZ ^{2,5}X_{NeuAc}Z
1567.6 107.0

Annotations:

Y
1572.4 156.0
1641.6 377.0

Annotations:

Y
1642.6 235.0
1709.5 421.0

Annotations:

B
1710.5 464.0

Annotations:

^{2,4}X_{GlcNAc}

There are 6 similar spectra:

Id Structure Score

2208

0.85

592

0.81

2338

0.76

2339

0.73

2527

0.70

432

0.68
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