In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.

PubMed Entry

GlyToucan Accession Number: G69752OZ

Peak Intensity
290.0 365.0

Annotations:

B
290.2 213.0

Annotations:

B
364.1 327.0

Annotations:

B
382.0 106.0

Annotations:

C
403.2 135.0

Annotations:

^{0,2}A_{GlcNAc}Y C^{1,3}X_{Man} ^{0,2}A_{Man}Y
407.2 128.0

Annotations:

Z
424.1 236.0

Annotations:

^{2,5}X_{GlcNAc}Y Y^{2,5}X_{GlcNAc} ^{1,5}A_{Gal} ^{1,3}A_{Man} ^{1,3}A_{Man}Y ^{0,4}A_{Man}Y ^{1,3}A_{Man}Y ^{2,4}A_{Man}Y C^{0,2}X_{Gal} C^{0,2}X_{Gal}
425.1 149.0

Annotations:

Y
525.1 415.0

Annotations:

^{0,3}A_{GlcNAc}Z B^{1,4}X_{Man}
527.3 112.0
536.2 269.0
544.0 381.0

Annotations:

C
616.3 111.0

Annotations:

C^{1,5}X_{NeuAc} CY ^{0,3}A_{Man} ^{1,4}A_{Man}Y
652.9 199.0
655.2 327.0

Annotations:

B
688.3 245.0

Annotations:

BY CZ
702.3 190.0

Annotations:

Y
753.3 171.0

Annotations:

Y^{1,5}X_{Gal} ^{1,5}X_{Gal} ^{1,3}X_{Man} C^{1,5}X_{NeuAc}
758.2 246.0
762.3 435.0

Annotations:

^{3,5}A_{GlcNAc}Y
762.8 246.0
774.1 229.0

Annotations:

Z
782.8 2290.0

Annotations:

Y
783.2 1188.0

Annotations:

Y
783.7 560.0

Annotations:

Y
784.4 337.0
803.8 259.0

Annotations:

B^{2,4}X_{NeuAc} ^{1,5}A_{Man}Z
813.9 126.0

Annotations:

^{0,2}X_{GlcNAc}Z Z^{0,2}X_{GlcNAc}
818.4 124.0

Annotations:

^{1,4}A_{GlcNAc} C^{0,3}X_{Gal} C^{1,4}X_{Gal} ^{1,4}X_{NeuAc}Z
819.4 155.0

Annotations:

^{1,4}A_{GlcNAc}Y ^{1,4}X_{GlcNAc}
835.0 298.0

Annotations:

C
835.3 1509.0

Annotations:

C
835.5 840.0

Annotations:

C
836.1 108.0
836.4 787.0
855.0 123.0

Annotations:

^{2,4}X_{GlcNAc} ^{0,2}X_{NeuAc}
855.3 191.0

Annotations:

^{2,4}X_{GlcNAc} ^{0,2}X_{NeuAc}
869.3 101.0
875.8 403.0

Annotations:

Z
876.4 165.0
876.9 392.0

Annotations:

^{1,3}A_{Man} ^{2,4}A_{Man}
884.9 381.0

Annotations:

Y
885.4 445.0
885.8 193.0
886.3 265.0
888.8 253.0
910.3 257.0

Annotations:

^{2,4}A_{GlcNAc}Y
911.5 113.0

Annotations:

YY
914.4 381.0
927.0 626.0
927.4 106.0
934.2 168.0

Annotations:

YZ ZY YZ ZY
935.8 1087.0

Annotations:

^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal}
936.4 961.0

Annotations:

^{2,5}A_{GlcNAc}Z
944.7 235.0
944.9 448.0
945.3 207.0
945.8 282.0
947.4 311.0
955.8 180.0
956.4 194.0
956.9 424.0
957.8 165.0
979.2 211.0

Annotations:

BY B^{3,5}X_{GlcNAc} CZ
1020.5 172.0
1095.1 102.0

Annotations:

^{2,4}A_{GlcNAc}Z B^{0,2}X_{Gal} ^{1,5}A_{Man}Z
1096.4 232.0

Annotations:

Z
1201.6 239.0

Annotations:

^{2,4}A_{GlcNAc}Y
1244.3 213.0
1276.5 704.0

Annotations:

Y
1277.5 105.0
1312.7 102.0
1329.8 226.0
1331.4 141.0

Annotations:

B^{3,5}X_{NeuAc}
1406.3 316.0
1418.5 137.0

Annotations:

BY CZ ^{3,5}A_{GlcNAc}Y
1420.4 135.0

Annotations:

C^{2,5}X_{Gal}
1462.6 135.0

Annotations:

B^{1,3}X_{NeuAc}
1479.5 128.0

Annotations:

Y
1479.8 217.0

Annotations:

Y
1483.6 179.0
1506.4 343.0

Annotations:

B
1507.3 227.0

Annotations:

Y^{1,5}X_{Gal} ^{1,5}X_{Gal} ^{1,3}X_{Man}
1524.6 304.0

Annotations:

C
1525.5 849.0
1569.6 313.0
1589.6 106.0

Annotations:

B^{0,2}X_{Gal} B^{0,4}X_{NeuAc}
1626.6 126.0

Annotations:

C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc}
1626.8 171.0

Annotations:

C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc}
1634.7 146.0
1641.7 708.0

Annotations:

Y
1642.5 255.0
1642.8 565.0
1643.3 198.0
1643.8 446.0
1645.8 221.0
1668.5 101.0
1709.6 219.0

Annotations:

B
1710.6 295.0

Annotations:

^{2,4}X_{GlcNAc}
1710.8 111.0

Annotations:

^{2,4}X_{GlcNAc}
1711.6 157.0

Annotations:

^{0,2}X_{NeuAc}
1712.5 343.0
1727.7 309.0

Annotations:

C
1727.9 342.0

Annotations:

C
1728.8 141.0
1729.4 114.0
1752.6 145.0

Annotations:

Z
1752.8 113.0

Annotations:

Z
1753.7 132.0

There are 6 similar spectra:

Id Structure Score

2208

0.75

2339

0.71

2338

0.70

2526

0.70

592

0.66

432

0.66
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