Recombinant mucin-type fusion proteins with Galα1,3Gal substitution as Clostridium difficile toxin A inhibitors

PubMed Entry

GlyToucan Accession Number: G52120NK

Peak Intensity
389.3 112.2

Annotations:

ZZ
406.19 22.0

Annotations:

^{0,4}A_{GalNAc}Z
407.11 56.7

Annotations:

YZ ZY
407.39 43.1

Annotations:

YZ ZY
416.24 21.2
424.29 55.0

Annotations:

^{1,5}A_{Gal} ^{0,4}A_{GalNAc}Y
470.1 19.0

Annotations:

C C
470.41 23.3

Annotations:

C C
473.69 18.1
509.18 46.6

Annotations:

Z^{1,3}X_{Gal} Z^{2,4}X_{GlcNAc} ^{1,3}X_{Gal}Z ^{2,4}X_{Gal}Z Z^{2,4}X_{Gal} ^{2,4}X_{GalNAc}Z
527.28 184.9

Annotations:

Y^{2,4}X_{GlcNAc} ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{2,4}X_{GalNAc}Y
537.43 50.4

Annotations:

^{0,4}X_{NeuAc}Z
569.34 2536.2

Annotations:

YZ ZY YZ ZY
570.38 70.8
570.67 28.3
581.28 56.7

Annotations:

B^{3,5}X_{Gal}
587.36 1450.1

Annotations:

YY YY
588.46 61.8
627.33 28.4

Annotations:

^{1,5}A_{GalNAc}Y ^{1,5}A_{GlcNAc} Z^{2,5}X_{Gal} ^{2,5}X_{Gal}Z
653.03 19.7
653.31 33.8
675.36 131.5

Annotations:

Y
675.69 53.5

Annotations:

Y
676.4 115.2
689.42 163.4

Annotations:

Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y
707.42 32.6
727.63 19.2
731.43 133.4

Annotations:

YZ ZY
745.54 126.8

Annotations:

^{0,3}A_{GalNAc} ^{1,4}X_{NeuAc}Z Z^{1,4}X_{NeuAc}
747.35 23.9

Annotations:

^{1,4}X_{GlcNAc} ^{1,4}X_{GalNAc}
749.44 10192.6

Annotations:

YY
750.6 273.7
783.46 22.8
791.45 96.6
800.48 31.4

Annotations:

^{0,4}X_{GlcNAc}Z ^{0,4}X_{Gal}Z Z^{0,4}X_{Gal} Z^{0,4}X_{GlcNAc}
819.54 99.0

Annotations:

^{0,2}X_{NeuAc}Y Y^{0,2}X_{NeuAc}
834.27 21.1

Annotations:

^{1,3}X_{NeuAc}Y Y^{1,3}X_{NeuAc}
834.6 21.9

Annotations:

Y^{1,3}X_{NeuAc} ^{1,3}X_{NeuAc}Y
842.52 252.6
858.41 90.8
858.82 22.3
859.35 44.3
859.78 23.4
860.38 89.8

Annotations:

Z Z
878.56 183.6

Annotations:

Y Y
879.44 120.4
879.75 30.9
890.41 88.3
891.46 24.0
902.58 47.7

Annotations:

^{0,4}X_{NeuAc}Z Z^{0,4}X_{NeuAc}
932.57 235.8

Annotations:

^{0,3}X_{Gal}Z Z^{0,3}X_{Gal} ^{0,3}X_{Gal}Z ^{0,3}X_{Gal}Z
933.48 42.8
944.45 25.7
956.42 25.4
962.5 2487.5

Annotations:

^{0,4}X_{Gal}Z ^{0,4}X_{GlcNAc}Z Z^{0,4}X_{Gal} Z^{0,4}X_{GlcNAc} ^{0,4}X_{Gal}Z ^{0,4}X_{Gal}Z
963.53 102.0
978.43 21.9

Annotations:

^{1,3}X_{NeuAc}Z Z^{1,3}X_{NeuAc}
978.81 18.3

Annotations:

^{1,3}X_{NeuAc}Z Z^{1,3}X_{NeuAc}
979.44 19.3
980.53 1031.8

Annotations:

Y^{0,4}X_{Gal} Y^{0,4}X_{GlcNAc} ^{0,4}X_{Gal}Y ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{Gal}Y ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{0,4}X_{GlcNAc}Y ^{0,4}X_{Gal}Y
981.22 48.5
981.53 80.7
996.56 564.0

Annotations:

^{1,3}X_{NeuAc}Y Y^{1,3}X_{NeuAc}
1004.15 39.0
1004.57 62.6
1020.42 273.7
1020.74 47.8
1021.57 428.4
1022.5 5642.5

Annotations:

Z Z
1023.47 264.1
1038.54 2936.1
1040.54 193163.7

Annotations:

Y Y
1041.55 10339.3
1042.68 416.5
1074.62 26.5
1082.46 40.1
1092.7 24.3
1110.44 46.9

Annotations:

^{0,2}X_{NeuAc} ^{0,2}X_{NeuAc}
1110.82 20.6

Annotations:

^{0,2}X_{NeuAc} ^{0,2}X_{NeuAc}
1175.77 40.0
1193.36 33.6
1193.64 29.3
1205.8 44.0
1209.52 20.1
1209.94 22.7
1235.75 21.7
1253.81 46.1
1269.63 251.4
1270.47 18.7
1270.94 51.2
1271.85 384.8

Annotations:

^{0,4}X_{Gal} ^{0,4}X_{GlcNAc} ^{0,4}X_{Gal}
1272.77 20.7
1285.6 43.2
1286.75 37.3
1287.65 4119.7

Annotations:

^{1,3}X_{NeuAc} ^{1,3}X_{NeuAc}
1288.56 130.3
1288.86 49.4
1289.08 22.9
1293.23 19.9
1295.62 391.9

There are 2 similar spectra:

Id Structure Score

502

0.93

82

0.93
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