In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.

PubMed Entry

GlyToucan Accession Number: G97205EG

Peak Intensity
434.1 279.0

Annotations:

B^{0,2}X_{NeuAc} B^{0,2}X_{NeuAc}
466.1 120.0

Annotations:

B^{1,3}X_{Gal} B^{0,4}X_{Gal} B^{2,4}X_{Gal}
653.1 417.0
702.2 396.0

Annotations:

Y Y
710.3 125.0
748.1 152.0
774.8 298.0

Annotations:

^{1,5}X_{NeuAc}Y Y^{1,5}X_{NeuAc} Y^{0,3}X_{Gal} ^{1,4}X_{Gal}Y
815.1 417.0
856.4 219.0

Annotations:

^{1,5}X_{NeuAc}Y Y^{1,5}X_{NeuAc} C^{2,4}X_{NeuAc} C^{2,4}X_{NeuAc}
884.8 149.0

Annotations:

Y Y
907.8 180.0

Annotations:

C
918.8 227.0
962.1 164.0

Annotations:

Z^{1,5}X_{Gal} ^{1,5}X_{Man}Z
963.8 100.0

Annotations:

^{1,4}A_{GlcNAc}
965.9 298.0

Annotations:

Y Y
974.3 257.0
979.3 273.0

Annotations:

BY BY CZ CZ
980.5 200.0

Annotations:

Y^{1,5}X_{Gal} ^{1,5}X_{Man}Y
1001.3 121.0

Annotations:

^{0,2}X_{NeuAc} ^{0,2}X_{NeuAc}
1008.9 323.0

Annotations:

C
1014.1 239.0
1023.8 182.0

Annotations:

^{3,5}X_{NeuAc} ^{3,5}X_{NeuAc}
1052.4 188.0
1058.4 226.0
1061.1 284.0

Annotations:

^{2,4}X_{NeuAc} ^{2,4}X_{NeuAc}
1069.5 183.0

Annotations:

^{0,3}A_{GlcNAc}Y ^{0,3}A_{GlcNAc}Y C^{1,4}X_{Man} C^{1,4}X_{Man}
1072.4 204.0
1072.8 138.0
1081.9 387.0
1089.5 195.0

Annotations:

^{1,3}X_{NeuAc} ^{1,3}X_{NeuAc}
1093.4 114.0
1094.0 700.0
1096.1 234.0

Annotations:

YZ ZY ZY YZ ZY YZ
1101.9 190.0
1102.5 1105.0
1102.9 3526.0
1103.4 1080.0
1216.5 128.0

Annotations:

^{1,3}X_{Man}Y Y^{1,3}X_{Man} Y^{0,4}X_{Gal} ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y
1234.6 189.0
1276.3 102.0

Annotations:

YY YY
1343.5 137.0

Annotations:

^{1,3}X_{NeuAc}Z Z^{1,3}X_{NeuAc}
1362.5 104.0

Annotations:

CY CY CY CY
1405.7 244.0

Annotations:

Y Y
1406.7 286.0
1461.7 392.0

Annotations:

YZ ZY ZY YZ
1479.6 144.0

Annotations:

YY YY
1562.6 201.0

Annotations:

^{3,5}A_{GlcNAc}Z ^{3,5}A_{GlcNAc}Z
1567.6 155.0

Annotations:

Y Y
1581.7 511.0

Annotations:

Y^{0,4}X_{Gal} ^{1,3}X_{Gal}Y ^{2,4}X_{Gal}Y
1599.8 112.0
1641.4 260.0

Annotations:

YY
1641.7 311.0

Annotations:

YY
1641.9 492.0

Annotations:

YY
1642.3 270.0
1643.6 459.0
1643.9 148.0
1644.7 314.0
1713.7 203.0

Annotations:

^{1,5}X_{NeuAc}Y Y^{1,5}X_{NeuAc}
1741.6 350.0

Annotations:

^{0,3}X_{NeuAc}Y Y^{0,3}X_{NeuAc}
1751.6 119.0
1753.0 280.0

Annotations:

Z Z
1753.6 183.0

Annotations:

B^{1,3}X_{NeuAc} B^{1,3}X_{NeuAc}
1770.7 741.0

Annotations:

Y Y
1771.7 215.0

Annotations:

C^{1,3}X_{NeuAc} C^{1,3}X_{NeuAc}
1772.7 499.0
1773.8 402.0
1854.6 418.0
1858.7 170.0

Annotations:

^{3,5}X_{Gal}
1914.7 453.0

Annotations:

Z Z
1915.7 378.0
1916.7 607.0
1917.7 109.0

Annotations:

C^{2,4}X_{NeuAc} C^{2,4}X_{NeuAc} ^{0,2}A_{GlcNAc}
1930.8 311.0
1931.8 124.0
1932.8 4582.0

Annotations:

Y Y
1933.8 4377.0
1934.7 2590.0
1935.7 1016.0
2070.0 177.0
2079.8 343.0
2081.0 127.0

There are 10 similar spectra:

Id Structure Score

2258

0.84

593

0.84

2553

0.83

569

0.83

2386

0.81

2387

0.81

2390

0.72

378

0.69

2392

0.62

616

0.55
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