In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.

PubMed Entry

GlyToucan Accession Number: G92186GL

Peak Intensity
303.3 306.0
330.0 136.0

Annotations:

C^{3,5}X_{NeuAc} BZ
364.1 121.0

Annotations:

BY BY CZ CZ ^{3,5}A_{Gal} BY CZ
408.0 135.0

Annotations:

B
511.4 221.0

Annotations:

B^{1,5}X_{GlcNAc} ^{0,3}X_{Gal}Y Y^{1,4}X_{Man} ^{0,3}X_{GlcNAc}Y
570.3 152.0

Annotations:

BY CZ ^{1,3}A_{Man} ^{0,4}A_{Man}Y ^{2,5}A_{Man}Y C^{0,2}X_{Gal} Y^{1,5}X_{Man} Y^{1,5}X_{Fuc} ^{1,5}X_{Gal}Y
620.7 417.0

Annotations:

Z
649.7 184.0

Annotations:

C^{0,2}X_{GlcNAc} Z^{0,2}X_{Fuc} Z^{2,5}X_{Gal}
655.1 264.0

Annotations:

B
659.9 301.0

Annotations:

C^{3,5}X_{NeuAc}
672.3 270.0

Annotations:

B
684.3 217.0
689.5 370.0

Annotations:

CY Y^{1,3}X_{Man}
714.2 218.0

Annotations:

^{0,4}X_{NeuAc}Z
746.3 152.0

Annotations:

^{3,5}A_{Man} ^{1,4}X_{GlcNAc}
750.8 495.0

Annotations:

Z^{0,2}X_{Fuc} Z^{2,5}X_{Gal} ^{0,2}X_{Gal}Z ^{2,5}X_{Gal}Z
754.8 205.0
765.3 427.0

Annotations:

^{2,4}A_{GlcNAc}Z B^{0,2}X_{Gal} B^{0,4}X_{NeuAc}
782.9 106.0

Annotations:

Y
783.4 305.0

Annotations:

Y
783.8 504.0

Annotations:

C^{2,4}X_{NeuAc}
784.4 263.0

Annotations:

C^{2,4}X_{NeuAc}
784.7 240.0

Annotations:

C^{2,4}X_{NeuAc}
785.4 166.0
792.2 123.0
807.3 339.0
817.1 332.0

Annotations:

B
817.4 143.0

Annotations:

B
831.4 147.0

Annotations:

^{1,5}A_{GlcNAc}Z B^{0,3}X_{NeuAc}
831.9 375.0

Annotations:

B^{0,3}X_{NeuAc} ^{1,5}A_{GlcNAc}Y Z^{0,2}X_{Fuc} Z^{2,5}X_{Gal} ^{0,2}X_{GlcNAc}Y
834.7 132.0

Annotations:

C
835.4 499.0

Annotations:

C
836.3 254.0
836.4 212.0
837.0 249.0

Annotations:

BZ
837.8 250.0

Annotations:

^{0,2}X_{NeuAc}Z
846.4 175.0

Annotations:

CZ ^{2,5}X_{NeuAc}Z BY ^{0,2}X_{NeuAc}Z
852.3 247.0

Annotations:

CY
855.3 158.0

Annotations:

CY ^{0,2}X_{NeuAc}Y ^{2,5}X_{NeuAc}Y Z^{3,5}X_{Fuc} ^{2,4}A_{GlcNAc}
855.9 126.0

Annotations:

^{2,4}A_{GlcNAc} ^{1,5}X_{NeuAc}Y Y^{0,3}X_{Fuc} Y^{3,5}X_{Gal} ^{3,5}X_{Gal}
856.4 590.0

Annotations:

^{1,5}X_{NeuAc}Y Y^{0,3}X_{Fuc} Y^{3,5}X_{Gal} ^{3,5}X_{Gal}
858.2 129.0
859.1 101.0
866.8 184.0

Annotations:

ZZ B^{0,2}X_{Gal} B^{0,4}X_{NeuAc}
867.8 517.0

Annotations:

B^{1,5}X_{Fuc}
870.3 230.0

Annotations:

^{0,3}X_{NeuAc}Y ^{3,5}X_{NeuAc}Y ^{0,3}A_{GlcNAc}
876.2 248.0

Annotations:

ZY YZ ^{2,4}A_{GlcNAc}Z C^{0,2}X_{Gal} C^{0,4}X_{NeuAc}
876.9 395.0

Annotations:

B^{2,4}X_{NeuAc} C^{1,5}X_{Fuc} ^{1,3}A_{Man} ^{2,4}A_{Man}
936.9 147.0
956.3 138.0
958.3 768.0

Annotations:

Y
958.9 307.0
966.4 334.0
966.8 550.0
967.5 444.0
971.6 172.0

Annotations:

^{1,5}X_{Gal}
996.9 207.0

Annotations:

CY
997.4 162.0

Annotations:

CY
1008.9 233.0

Annotations:

^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{1,5}A_{GlcNAc}Y
1009.2 245.0

Annotations:

^{0,4}X_{Gal} ^{1,3}X_{Gal} ^{2,4}X_{Gal} ^{1,3}X_{Fuc} ^{2,4}X_{Fuc} ^{1,5}A_{GlcNAc}Y
1009.8 446.0

Annotations:

^{1,5}A_{GlcNAc}Y ^{3,5}X_{Fuc}
1012.4 163.0
1013.8 299.0
1029.3 409.0
1030.4 533.0
1057.5 327.0
1080.3 169.0

Annotations:

YZ ZY
1196.6 299.0

Annotations:

^{0,3}X_{NeuAc}Z
1201.6 241.0

Annotations:

^{2,4}A_{GlcNAc}Y
1224.5 123.0

Annotations:

ZZ
1242.5 104.0

Annotations:

Z
1373.5 158.0

Annotations:

^{0,3}X_{GlcNAc}Y
1405.4 298.0

Annotations:

Y
1406.5 209.0
1408.7 235.0
1509.5 300.0
1518.0 113.0

Annotations:

^{0,3}X_{Gal}Z Z^{1,4}X_{Fuc} Z^{0,3}X_{Gal} Z^{1,4}X_{Gal}
1551.5 250.0

Annotations:

B^{2,4}X_{NeuAc} ^{0,3}X_{Gal}Y ^{3,5}X_{Gal}Y Y^{0,3}X_{Fuc} Y^{3,5}X_{Gal} ^{3,5}X_{GlcNAc}
1552.6 123.0

Annotations:

C^{1,5}X_{Fuc}
1565.5 165.0

Annotations:

Y^{0,4}X_{Gal} Y^{1,3}X_{Gal} Y^{2,4}X_{Gal} ^{0,4}X_{Gal}Y Y^{1,3}X_{Fuc} Y^{2,4}X_{Fuc} ^{2,4}X_{GlcNAc}
1567.7 532.0

Annotations:

Y
1568.7 1286.0
1569.6 1210.0

Annotations:

C^{2,4}X_{NeuAc}
1570.3 141.0
1570.5 558.0
1571.4 263.0
1571.9 247.0
1572.6 103.0
1645.6 348.0
1674.6 104.0
1675.6 140.0

Annotations:

BZ
1694.7 830.0
1707.6 119.0

Annotations:

^{0,3}X_{NeuAc}Z
1709.5 100.0

Annotations:

BY CZ ^{2,5}X_{NeuAc}Z Z^{1,3}X_{Fuc} Z^{2,4}X_{Fuc} Z^{0,4}X_{Gal} Z^{1,3}X_{Gal} Z^{2,4}X_{Gal}
1735.5 437.0

Annotations:

B^{0,2}X_{Gal} B^{0,4}X_{NeuAc}
1736.5 134.0
1736.7 401.0
1737.0 109.0

There are 3 similar spectra:

Id Structure Score

373

0.62

2360

0.59

2249

0.58
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