In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.

PubMed Entry

GlyToucan Accession Number: G19592AH

Peak Intensity
324.1 165.0
341.2 106.0

Annotations:

C C C
342.1 113.0
383.2 186.0

Annotations:

^{0,2}A_{Man} ^{0,4}A_{Man} ^{1,3}A_{Man} ^{1,3}A_{Man}Y ^{1,3}A_{Man} ^{2,4}A_{Man} ^{1,3}A_{Man}Y ^{2,4}A_{Man}Y
425.9 111.0
432.1 125.0

Annotations:

^{3,5}A_{GlcNAc}Z
467.1 213.0

Annotations:

BZ BZ BZ
485.1 1085.0

Annotations:

B
486.3 535.0
503.1 484.0

Annotations:

C
503.4 140.0

Annotations:

C
575.1 172.0

Annotations:

^{1,4}A_{Man} CY ^{0,3}A_{Man}Y ^{0,3}A_{Man}Y ^{1,4}A_{Man}Y
631.2 243.0
633.8 108.0
647.2 319.0

Annotations:

B
665.1 542.0

Annotations:

C
677.2 350.0

Annotations:

CY ^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y
677.8 244.0
703.2 112.0

Annotations:

^{3,5}A_{Man}Z ^{3,5}A_{Man}Z
758.3 1016.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y
758.6 229.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y
759.2 144.0
765.2 184.0

Annotations:

^{3,5}A_{GlcNAc}Y ^{3,5}A_{GlcNAc}Y ^{3,5}A_{GlcNAc}Y
789.4 102.0
791.2 196.0

Annotations:

BZ
801.7 179.0
809.3 530.0

Annotations:

B B
810.3 374.0
822.3 290.0
826.8 172.0

Annotations:

C
827.2 553.0

Annotations:

C
827.4 645.0

Annotations:

C
829.8 141.0

Annotations:

BY BY BY CZ CZ CZ
830.3 521.0
831.4 198.0
839.2 1810.0

Annotations:

CY CY CY ^{2,4}A_{GlcNAc}
839.8 979.0
840.3 840.0
841.2 213.0
847.0 376.0
851.8 142.0
860.2 740.0

Annotations:

Y Y Y
860.7 328.0

Annotations:

Y Y Y
861.1 370.0

Annotations:

^{2,5}A_{GlcNAc}
861.3 338.0

Annotations:

^{2,5}A_{GlcNAc}
861.8 145.0
869.2 175.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{0,4}A_{Man} ^{0,2}A_{GlcNAc}
869.4 357.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{0,4}A_{Man} ^{0,2}A_{GlcNAc}
870.3 151.0
884.8 374.0
899.0 243.0

Annotations:

^{0,3}A_{GlcNAc}Y ^{0,3}A_{Man}
899.3 113.0

Annotations:

^{0,3}A_{GlcNAc}Y ^{0,3}A_{Man}
900.2 326.0
904.8 183.0
910.8 349.0

Annotations:

B
911.4 300.0

Annotations:

^{0,2}A_{GlcNAc}Z YY
911.8 256.0

Annotations:

YY
912.3 452.0
913.9 508.0
920.3 185.0

Annotations:

C
925.5 193.0
932.3 311.0

Annotations:

Z Z Z
932.8 661.0

Annotations:

Z Z Z
936.3 157.0
941.2 525.0

Annotations:

Y Y Y
941.4 196.0

Annotations:

Y Y Y
941.8 627.0

Annotations:

Y Y Y
942.3 178.0
942.8 580.0
948.8 138.0
962.3 356.0
962.8 219.0
971.3 895.0

Annotations:

BY CZ
971.8 221.0

Annotations:

BY CZ
976.3 131.0
980.7 267.0
986.3 175.0
992.4 3000.0
992.7 1053.0
992.8 1009.0
993.4 385.0
993.8 245.0
1001.4 220.0
1001.9 115.0
1002.4 318.0
1002.8 263.0
1003.3 274.0
1003.8 596.0
1012.3 268.0

Annotations:

BY CZ
1012.9 331.0

Annotations:

^{2,4}A_{GlcNAc}Z
1013.8 434.0

Annotations:

^{2,4}A_{GlcNAc}Z
1164.6 112.0
1177.5 164.0
1235.3 143.0

Annotations:

Y
1355.4 256.0

Annotations:

^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y ^{2,4}A_{GlcNAc}Y
1397.3 354.0

Annotations:

Y
1399.3 230.0

Annotations:

^{2,5}A_{GlcNAc}Y ^{2,5}A_{GlcNAc}Y ^{2,5}A_{GlcNAc}Y ^{2,5}A_{Man}Y ^{2,5}A_{Man}Y ^{2,5}A_{Man}Y
1400.6 277.0
1476.1 143.0
1604.5 128.0
1621.5 237.0
1661.6 115.0
1679.6 257.0

Annotations:

^{2,4}A_{GlcNAc}
1681.6 192.0
1701.6 124.0
1722.5 118.0
1723.8 104.0

Annotations:

^{2,5}A_{GlcNAc}
1822.5 235.0

Annotations:

B
1823.6 479.0
1824.8 112.0
1883.8 151.0

Annotations:

Y Y Y
1885.5 134.0

There are 4 similar spectra:

Id Structure Score

566

0.69

2358

0.65

591

0.61

614

0.59
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